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RAP1 / YNL216W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
GRF1 17 , TBA1 , TUF1
Protein Product
DNA-binding transcription factor RAP1
Feature Type
ORF , Verified
Description
Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation, repression, chromatin silencing, telomere length maintenance; relocalizes to cytosol under hypoxia; conserved protein with N-terminal BRCT domain, central region with homology to Myb DNA binding domain, and C-terminal Rap1-specific protein-interaction domain (RCT domain); recruits Sir complex to telomeric DNA; present in quiescent cell telomere hyperclusters 2 3 4 5 6 7 8 9

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