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SRP1 / YNL189W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
KAP60 , SCM1
Protein Product
karyopherin alpha
Feature Type
ORF , Verified
Description
Karyopherin alpha homolog; forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; involved in cotranslational protein degradation; binds ribosome-bound nascent polypeptides; Srp1p and Sts1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation 2 3 4

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