Literature Help
ALF1 / YNL148C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Hurst Z, et al. (2022) A distinct P-body-like granule is induced in response to the disruption of microtubule integrity in Saccharomyces cerevisiae. Genetics 222(1) PMID:35876801
- Baruffini E, et al. (2020) Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study. Sci Rep 10(1):10524 PMID:32601343
- Li G and Moore JK (2020) Microtubule dynamics at low temperature: evidence that tubulin recycling limits assembly. Mol Biol Cell 31(11):1154-1166 PMID:32213119
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Kang X, et al. (2014) Pump-free multi-well-based microfluidic system for high-throughput analysis of size-control relative genes in budding yeast. Integr Biol (Camb) 6(7):685-93 PMID:24872017
- Naicker MC, et al. (2012) Identification of chaperones in freeze tolerance in Saccharomyces cerevisiae. J Microbiol 50(5):882-7 PMID:23124761
- Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30 PMID:22177309
- Ruotolo R, et al. (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67 PMID:18394190
- Kumar A, et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 PMID:11914276
- Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 PMID:9885248
- Tian G, et al. (1997) Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. J Cell Biol 138(4):821-32 PMID:9265649
- Nasr F, et al. (1996) The sequence of 36.8 kb from the left arm of chromosome XIV reveals 24 complete open reading frames: 18 correspond to new genes, one of which encodes a protein similar to the human myotonic dystrophy kinase. Yeast 12(2):169-75 PMID:8686380
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Gartz Hanson M, et al. (2016) Novel α-tubulin mutation disrupts neural development and tubulin proteostasis. Dev Biol 409(2):406-19 PMID:26658218
- Nithianantham S, et al. (2015) Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics. Elife 4 PMID:26208336
- Haldar S, et al. (2012) High copies of SUM1 enhance the stability of wild-type microtubules against adverse conditions in Saccharomyces cerevisiae. Biochem Biophys Res Commun 418(3):525-30 PMID:22285862
- Yibmantasiri P, et al. (2012) Molecular basis for fungicidal action of neothyonidioside, a triterpene glycoside from the sea cucumber, Australostichopus mollis. Mol Biosyst 8(3):902-12 PMID:22271309
- North M, et al. (2011) Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast. PLoS One 6(8):e24205 PMID:21912624
- Sun Z, et al. (2011) Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. PLoS Biol 9(4):e1000614 PMID:21541367
- Grassl J, et al. (2010) Analysis of the budding yeast pH 4-7 proteome in meiosis. Proteomics 10(3):506-19 PMID:20029842
- Bivi N, et al. (2009) Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection. Genome Biol 10(9):R93 PMID:19744312
- Metzger MB and Michaelis S (2009) Analysis of quality control substrates in distinct cellular compartments reveals a unique role for Rpn4p in tolerating misfolded membrane proteins. Mol Biol Cell 20(3):1006-19 PMID:19073890
- Kim M, et al. (2008) Impairment of microtubule system increases alpha-synuclein aggregation and toxicity. Biochem Biophys Res Commun 365(4):628-35 PMID:18022384
- Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24 PMID:18629161
- Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 PMID:14671320
- Bhamidipati A, et al. (2000) ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin. J Cell Biol 149(5):1087-96 PMID:10831612
- Grava S, et al. (2000) Functional analysis of six genes from chromosomes XIV and XV of Saccharomyces cerevisiae reveals YOR145c as an essential gene and YNL059c/ARP5 as a strain-dependent essential gene encoding nuclear proteins. Yeast 16(11):1025-33 PMID:10923024
Reviews
No reviews curated.
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Naicker MC, et al. (2012) Identification of chaperones in freeze tolerance in Saccharomyces cerevisiae. J Microbiol 50(5):882-7 PMID:23124761
- Ruotolo R, et al. (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67 PMID:18394190
- Tian G, et al. (1997) Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. J Cell Biol 138(4):821-32 PMID:9265649
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Carey SB, et al. (2023) A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. G3 (Bethesda) 13(1) PMID:36409020
- Cohen N, et al. (2023) A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon. EMBO J 42(11):e113385 PMID:37073826
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Hurst Z, et al. (2022) A distinct P-body-like granule is induced in response to the disruption of microtubule integrity in Saccharomyces cerevisiae. Genetics 222(1) PMID:35876801
- Girstmair H, et al. (2019) The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range. Nat Commun 10(1):3626 PMID:31399574
- Gonzales-Zubiate FA, et al. (2017) Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae. J Biol Chem 292(29):12267-12284 PMID:28539363
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Van de Vosse DW, et al. (2013) A role for the nucleoporin Nup170p in chromatin structure and gene silencing. Cell 152(5):969-83 PMID:23452847
- Chesi A, et al. (2012) The role of the Parkinson's disease gene PARK9 in essential cellular pathways and the manganese homeostasis network in yeast. PLoS One 7(3):e34178 PMID:22457822
- Haldar S, et al. (2012) High copies of SUM1 enhance the stability of wild-type microtubules against adverse conditions in Saccharomyces cerevisiae. Biochem Biophys Res Commun 418(3):525-30 PMID:22285862
- Moehle EA, et al. (2012) The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. PLoS Genet 8(11):e1003101 PMID:23209445
- Echtenkamp FJ, et al. (2011) Global functional map of the p23 molecular chaperone reveals an extensive cellular network. Mol Cell 43(2):229-41 PMID:21777812
- Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78 PMID:21460040
- Hang M and Smith MM (2011) Genetic analysis implicates the Set3/Hos2 histone deacetylase in the deposition and remodeling of nucleosomes containing H2A.Z. Genetics 187(4):1053-66 PMID:21288874
- Scherrer T, et al. (2011) Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Genome Biol 12(1):R3 PMID:21232131
- Vembar SS, et al. (2010) J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem 285(29):22484-94 PMID:20430885
- Hasegawa Y, et al. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA 14(11):2333-47 PMID:18805955
- Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74 PMID:18676811
- Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 PMID:16487579
- Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1:2005.0026 PMID:16729061
- Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 PMID:9885248
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Mota MN, et al. (2024) Shared and more specific genetic determinants and pathways underlying yeast tolerance to acetic, butyric, and octanoic acids. Microb Cell Fact 23(1):71 PMID:38419072
- Pallares RM, et al. (2022) Identifying Toxicity Mechanisms Associated with Early Lanthanide Exposure through Multidimensional Genome-Wide Screening. ACS Omega 7(38):34412-34419 PMID:36188298
- Ogbede JU, et al. (2021) A genome-wide portrait of pervasive drug contaminants. Sci Rep 11(1):12487 PMID:34127714
- Papagiannidis D, et al. (2021) Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex. EMBO J 40(22):e107958 PMID:34617598
- Baruffini E, et al. (2020) Mechanistic insights on the mode of action of an antiproliferative thiosemicarbazone-nickel complex revealed by an integrated chemogenomic profiling study. Sci Rep 10(1):10524 PMID:32601343
- Wilcox A, et al. (2020) Sulforaphane alters the acidification of the yeast vacuole. Microb Cell 7(5):129-138 PMID:32391394
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Hoepfner D, et al. (2014) High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions. Microbiol Res 169(2-3):107-20 PMID:24360837
- Knechtle P, et al. (2014) The natural diyne-furan fatty acid EV-086 is an inhibitor of fungal delta-9 fatty acid desaturation with efficacy in a model of skin dermatophytosis. Antimicrob Agents Chemother 58(1):455-66 PMID:24189258
- Pereira FB, et al. (2014) Genome-wide screening of Saccharomyces cerevisiae genes required to foster tolerance towards industrial wheat straw hydrolysates. J Ind Microbiol Biotechnol 41(12):1753-61 PMID:25287021
- Gaytán BD, et al. (2013) A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture. PLoS One 8(11):e81253 PMID:24260565
- Lis M, et al. (2013) Chemical genomic screening of a Saccharomyces cerevisiae genomewide mutant collection reveals genes required for defense against four antimicrobial peptides derived from proteins found in human saliva. Antimicrob Agents Chemother 57(2):840-7 PMID:23208710
- Marek A and Korona R (2013) Restricted pleiotropy facilitates mutational erosion of major life-history traits. Evolution 67(11):3077-86 PMID:24151994
- Tun NM, et al. (2013) Disulfide stress-induced aluminium toxicity: molecular insights through genome-wide screening of Saccharomyces cerevisiae. Metallomics 5(8):1068-75 PMID:23832094
- Zhang L, et al. (2013) The transcriptional control machinery as well as the cell wall integrity and its regulation are involved in the detoxification of the organic solvent dimethyl sulfoxide in Saccharomyces cerevisiae. FEMS Yeast Res 13(2):200-18 PMID:23157175
- Kim H, et al. (2012) Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeast. J Biol Chem 287(23):19029-39 PMID:22511765
- Lickwar CR, et al. (2012) Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function. Nature 484(7393):251-5 PMID:22498630
- North M, et al. (2012) Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae. PLoS Genet 8(6):e1002699 PMID:22685415
- Orij R, et al. (2012) Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae. Genome Biol 13(9):R80 PMID:23021432
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Yibmantasiri P, et al. (2012) Molecular basis for fungicidal action of neothyonidioside, a triterpene glycoside from the sea cucumber, Australostichopus mollis. Mol Biosyst 8(3):902-12 PMID:22271309
- Ratnakumar S, et al. (2011) Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae. Mol Biosyst 7(1):139-49 PMID:20963216
- Villa-García MJ, et al. (2011) Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics 285(2):125-49 PMID:21136082
- Alamgir M, et al. (2010) Chemical-genetic profile analysis of five inhibitory compounds in yeast. BMC Chem Biol 10:6 PMID:20691087
- Auesukaree C, et al. (2009) Genome-wide identification of genes involved in tolerance to various environmental stresses in Saccharomyces cerevisiae. J Appl Genet 50(3):301-10 PMID:19638689
- Watanabe M, et al. (2009) Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth. Curr Genet 55(4):365-80 PMID:19466415
- Cipollina C, et al. (2008) Saccharomyces cerevisiae SFP1: at the crossroads of central metabolism and ribosome biogenesis. Microbiology (Reading) 154(Pt 6):1686-1699 PMID:18524923
- Sinha H, et al. (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180(3):1661-70 PMID:18780730
- Brown JA, et al. (2006) Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol Syst Biol 2:2006.0001 PMID:16738548
- Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36 PMID:16911514
- Deutschbauer AM, et al. (2005) Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 169(4):1915-25 PMID:15716499
- Dudley AM, et al. (2005) A global view of pleiotropy and phenotypically derived gene function in yeast. Mol Syst Biol 1:2005.0001 PMID:16729036
- Hellauer K, et al. (2005) Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae. Mol Pharmacol 68(5):1365-75 PMID:16061773
- Xie MW, et al. (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20 PMID:15883373
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Cohen BA, et al. (2002) Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks. Mol Biol Cell 13(5):1608-14 PMID:12006656
- Deutschbauer AM, et al. (2002) Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 99(24):15530-5 PMID:12432101
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400 PMID:12089449