Phenotype Help

SRV2 / YNL138W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant exhibits slow growth, an abnormal actin cytoskeleton, and reduced localization of proteins to the bud tip; in large-scale studies, null mutant fails to respire or to mate, has abnormally large cells with elongated buds and abnormal lipid particle morphology, is sensitive to hyperosmotic and oxidative stress, and is resistant to K28 killer toxin and to manganese; conditional mutant exhibits chromosome instability at semi-permissive temperature; overexpression in the Sigma1278b genetic background causes greatly increased filamentous growth; null mutant exhibits filamentous growth in response to HU treatment; diploid heterozygous null mutant is sensitive to starvation and heat; null mutant is sensitive to a variety of chemicals

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


Resources