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NMA111 / YNL123W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

YNM3 3
Feature Type
ORF , Verified
Serine protease and general molecular chaperone; cleaves Roq1p, which modifies the substrate specificity of the Ubr1p Ub-ligase, promoting the stress-induced homeostatically-regulated protein degradation (SHRED) of misfolded and native ER-membrane and cytosolic proteins; chaperone activity involved in the heat stress response; promotes apoptosis through proteolysis of Bir1p; role in lipid homeostasis; mammalian Omi/HtrA2 serine protease family member 1 2 3 4 5