PHO23 / YNL097C Gene Ontology

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code. SGD has manually curated and high-throughput GO Annotations, both derived from the literature, as well as computational, or predicted, annotations.

Summary

Histone-binding component of the Rpd3L histone deacetylase complex involved in chromatin organization, modification, and silencing at telomeres, the rDNA, and the mating-type cassette; regulates transcription in response to stressors such as heat and glucose limitation

GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

ion binding, protein-macromolecule adaptor activity, chromatin organization, response to heat, response to stress, nucleus, organelle, Rpd3L complex, Rpd3L-Expanded complex, Sin3-type complex, histone deacetylase complex

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Manually Curated

Manually curated GO annotations reflect our best understanding of the basic molecular function, biological process, and cellular component for this gene product. Manually curated annotations are assigned by SGD curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all manually curated GO annotations for accuracy and completeness.

High-throughput

GO annotations from high-throughput experiments are based on a variety of large scale high-throughput experiments, including genome-wide experiments. Many of these annotations are made based on GO annotations (or mappings to GO annotations) assigned by the authors, rather than SGD curators. While SGD curators read these publications and often work closely with authors to incorporate the information, each individual annotation may not necessarily be reviewed by a curator. GO annotations from high-throughput experiments will be assigned only when this type of data is available, and thus may not be assigned to terms from all three controlled vocabularies of the Gene Ontology.

There are no high-throughput annotations for PHO23.

Computational

Computational GO Annotations are predictions. These annotations are NOT reviewed by a curator. Currently, all computational GO annotations for S. cerevisiae are assigned by an external source (for example, the Gene Ontology Annotation (GOA) project of the European Bioinformatics Institute (EBI)).

There are no computational annotations for PHO23.

Shared Annotations

This diagram displays manually curated and high-throughput GO terms (green squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of GO terms shared (adjustable using the slider at the bottom).