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APJ1 / YNL077W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Feature Type
ORF , Verified
Description
Hsp40 chaperone with a role in SUMO-mediated protein degradation; works in concert with Hsp70 and Hsp110 (Sse1p) to promote disaggregation of intranuclear protein inclusions; competes with Hsp104 in disaggregation, supporting turnover instead of refolding; member of DnaJ-like family, conserved across eukaryotes; overexpression interferes with propagation of the [Psi+] prion; forms nuclear foci upon DNA replication stress 1 2 3 4 5

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