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SSN8 / YNL025C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

GIG3 4 , NUT9 8 , CycC 9 , RYE2 , SRB11 2 , UME3 10 , CNC1 11
Protein Product
cyclin-dependent protein serine/threonine kinase regulator SSN8
Feature Type
ORF , Verified
Cyclin-like component of RNA polymerase II holoenzyme; involved in phosphorylation of RNAPII C-terminal domain; forms kinase-cyclin pair in RNAPII holoenzyme with Ssn3p; needed for entry into and execution of meiotic program; involved in glucose repression, telomere maintenance; degraded in response to nitrogen starvation, and also to oxidative stress, but in different cellular compartments, and with different cellular outcomes; 35% identical to human cyclin C 2 3 4 5 6 7