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COA6 / YMR244C-A Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Feature Type
ORF , Verified
Description
Protein involved in cytochrome c oxidase (Complex IV) assembly; involved in delivery of copper to Complex IV; also required for efficient formation of respiratory supercomplexes comprised of Complexes III and IV; localizes to the mitochondrial intermembrane space; ortholog implicated in cardiac defects in zebrafish and human; transcription is induced in response to the DNA-damaging agent MMS; protein abundance increases in response to DNA replication stress 1 2 3 4

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