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MRE11 / YMR224C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
RAD58 , XRS4 , NGS1 28
Protein Product
MRX complex nuclease subunit
Feature Type
ORF , Verified
Description
Nuclease subunit of the MRX complex with Rad50p and Xrs2p; complex functions in repair of DNA double-strand breaks and in telomere stability; Mre11p associates with Ser/Thr-rich ORFs in premeiotic phase; nuclease activity required for MRX function; widely conserved; forms nuclear foci upon DNA replication stress 2 3 4 6 7

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