Phenotype Help

GYL1 / YMR192W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

10 entries for 7 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: gyl1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.995
Breslow DK, et al. (2008) PMID:18622397
metal resistance: increased
classical geneticsnull
Allele: gyl1-Δ
S288C0.8 nm 11-atom gold core, functionalized with positively-charged N,N,N trimethylammoniumethanethiol (TMAT) gold nanoparticleDetails: viability assayed after 24-hr incubation with gold particles in water
Smith MR, et al. (2013) PMID:23144132
resistance to chemicals: decreased
homozygous diploid, systematic mutation setnull
Allele: gyl1-Δ
S288C0.05 mM chromium trioxideDetails: growth impaired by at least 50% relative to wt upon exposure to hexavalent chromium [Cr(vi)]
Johnson AJ, et al. (2016) PMID:27146641
resistance to chemicals: decreased
heterozygous diploid, systematic mutation set null
Allele: gyl1-Δ
S288C20 μg/mL actinomycin DLum PY, et al. (2004) PMID:14718172
resistance to chemicals: increased
large-scale surveynull
Allele: gyl1-Δ
S288C5 ug/ml L-canavanineShi Y, et al. (2011) PMID:21880895
resistance to chemicals: increased
systematic mutation setnull
Allele: gyl1-Δ
S288C15 mg/l valinomycinJakubkova M, et al. (2016) PMID:27711131
silencing: decreased
systematic mutation set null
Allele: gyl1-Δ
S288CDetails: decreased silencing at the silent mating type locus HMR based on expression of integrated URA3; confirmed using a Bioscreen mini-liquid culture assay
Liu Q, et al. (2020) PMID:32469861
silencing: decreased
classical genetics null
Allele: gyl1-Δ
S288CDetails: decreased silencing at the silent mating type locus HMR based on expression of integrated URA3 using conventional spot tests
Liu Q, et al. (2020) PMID:32469861
starvation resistance: decreased
heterozygous diploid, competitive growth

pooled mutant strains were subjected to low nutrient stress, then dead cells were separated and their mutations identified

null
Allele: gyl1-Δ
S288CDavey HM, et al. (2012) PMID:22356628
viable
systematic mutation setnull
Allele: gyl1-Δ
S288CGiaever G, et al. (2002) PMID:12140549
Showing 1 to 10 of 10 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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