Sequence Help

MLH1 / YMR167W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

PMS2 17
Protein Product
mismatch repair ATPase MLH1
Feature Type
ORF , Verified
Protein required for mismatch repair in mitosis and meiosis; also required for crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; required for silencing at the silent mating-type loci and telomeres; human homolog is associated with hereditary non-polyposis colon cancer 1 2 3 4 5