Phenotype Help

RIM11 / YMR139W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant is sensitive to starvation, does not sporulate, has small nucleolus, decreased silencing, is resistant to methotrexate, defective in endocytosis, has shortened lifespan, accumulates metals; overexpression exacerbates metal toxicity, confers sensitivity to rapamycin

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

27 entries for 18 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: increased
systematic mutation setnull
Allele: rim11-Δ
S288C cadmium cationYu D, et al. (2012) PMID:23151179
chemical compound accumulation: increased
systematic mutation setnull
Allele: rim11-Δ
S288C nickel cationYu D, et al. (2012) PMID:23151179
chronological lifespan: decreased
competitive growth

competitive survival of mixed stationary phase co-cultures

null
Allele: rim11-Δ
S288CGaray E, et al. (2014) PMID:24586198
competitive fitness: decreased
systematic mutation setnull
Allele: rim11-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: rim11-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: rim11-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: rim11-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.978
Breslow DK, et al. (2008) PMID:18622397
endocytosis: decreased
systematic mutation setnull
Allele: rim11-Δ
S288CDetails: defective internalization of a chimeric Snc1p reporter, GFP-Snc1-Suc2
Burston HE, et al. (2009) PMID:19506040
filamentous growth: increased
systematic mutation setoverexpressionSigma1278bJin R, et al. (2008) PMID:17989363
invasive growth: increased
homozygous diploid, systematic mutation setoverexpressionSigma1278bMedia: nitrogen-sufficient medium
Details: agar invasion score: 0.98; enhanced pseudohyphal growth, based on elevated invasiveness
Shively CA, et al. (2013) PMID:23410832
Showing 1 to 10 of 27 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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