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CSM3 / YMR048W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Batra S, et al. (2025) G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation. Science 387(6738):eadt1978 PMID:40048517
- Keszthelyi A, et al. (2024) The fork protection complex generates DNA topological stress-induced DNA damage while ensuring full and faithful genome duplication. Proc Natl Acad Sci U S A 121(49):e2413631121 PMID:39589889
- Westhorpe R, et al. (2024) Mechanisms controlling replication fork stalling and collapse at topoisomerase 1 cleavage complexes. Mol Cell 84(18):3469-3481.e7 PMID:39236719
- Gordon MR, et al. (2023) Suppression of chromosome instability by targeting a DNA helicase in budding yeast. Mol Biol Cell 34(1):ar3 PMID:36350688
- Shrestha S, et al. (2023) Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors. Chromosoma 132(2):117-135 PMID:37166686
- Sulaiman AA, et al. (2023) Mft1, identified from a genome-wide screen of the yeast haploid mutants, mediates cell cycle arrest to counteract quinoxaline-induced toxicity. Front Genet 14:1296383 PMID:38283148
- Baretić D, et al. (2020) Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork. Mol Cell 78(5):926-940.e13 PMID:32369734
- Grabarczyk DB (2020) Crystal structure and interactions of the Tof1-Csm3 (Timeless-Tipin) fork protection complex. Nucleic Acids Res 48(12):6996-7004 PMID:32469068
- Matmati N, et al. (2020) Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. Mol Cell Biol 40(12) PMID:32205408
- Srinivasan M, et al. (2020) Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs. Elife 9 PMID:32515737
- Westhorpe R, et al. (2020) Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress. Nucleic Acids Res 48(21):12169-12187 PMID:33166393
- Hizume K, et al. (2018) DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier. Genes Dev 32(19-20):1315-1320 PMID:30232092
- Langston LD, et al. (2017) Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks. Elife 6 PMID:28869037
- Lewis JS, et al. (2017) Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome. Proc Natl Acad Sci U S A 114(40):10630-10635 PMID:28923950
- Litwin I, et al. (2017) The LSH/HELLS homolog Irc5 contributes to cohesin association with chromatin in yeast. Nucleic Acids Res 45(11):6404-6416 PMID:28383696
- Puddu F, et al. (2017) Chromatin determinants impart camptothecin sensitivity. EMBO Rep 18(6):1000-1012 PMID:28389464
- Yeeles JTP, et al. (2017) How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication. Mol Cell 65(1):105-116 PMID:27989442
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Aksenova AY, et al. (2015) Expansion of Interstitial Telomeric Sequences in Yeast. Cell Rep 13(8):1545-51 PMID:26586439
- Maculins T, et al. (2015) Tethering of SCF(Dia2) to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase. Curr Biol 25(17):2254-9 PMID:26255844
- Schalbetter SA, et al. (2015) Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability. Proc Natl Acad Sci U S A 112(33):E4565-70 PMID:26240319
- Murakami H and Keeney S (2014) Temporospatial coordination of meiotic DNA replication and recombination via DDK recruitment to replisomes. Cell 158(4):861-873 PMID:25126790
- Uzunova SD, et al. (2014) The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence. Cell Div 9:4 PMID:25379053
- Alver B, et al. (2013) Novel checkpoint pathway organization promotes genome stability in stationary-phase yeast cells. Mol Cell Biol 33(2):457-72 PMID:23149941
- Borges V, et al. (2013) An Eco1-independent sister chromatid cohesion establishment pathway in S. cerevisiae. Chromosoma 122(1-2):121-34 PMID:23334284
- LeClere AR, et al. (2013) The role of CSM3, MRC1, and TOF1 in minisatellite stability and large loop DNA repair during meiosis in yeast. Fungal Genet Biol 50:33-43 PMID:23165348
- Sengupta S, et al. (2013) Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Curr Biol 23(7):543-52 PMID:23499531
- Zhang Y, et al. (2013) Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination. PLoS Genet 9(12):e1003979 PMID:24339793
- Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 PMID:22842922
- Bairwa NK, et al. (2011) The intra-S phase checkpoint protein Tof1 collaborates with the helicase Rrm3 and the F-box protein Dia2 to maintain genome stability in Saccharomyces cerevisiae. J Biol Chem 286(4):2445-54 PMID:21087929
- Vaisica JA, et al. (2011) Mms1 and Mms22 stabilize the replisome during replication stress. Mol Biol Cell 22(13):2396-408 PMID:21593207
- Moriel-Carretero M and Aguilera A (2010) A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51- or Pol32-mediated restart mechanisms. Mol Cell 37(5):690-701 PMID:20227372
- Theis JF, et al. (2010) The DNA damage response pathway contributes to the stability of chromosome III derivatives lacking efficient replicators. PLoS Genet 6(12):e1001227 PMID:21151954
- Bando M, et al. (2009) Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284(49):34355-65 PMID:19819872
- Fernius J and Marston AL (2009) Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. PLoS Genet 5(9):e1000629 PMID:19730685
- Mohanty BK, et al. (2009) Contrasting roles of checkpoint proteins as recombination modulators at Fob1-Ter complexes with or without fork arrest. Eukaryot Cell 8(4):487-95 PMID:19234097
- Andersen MP, et al. (2008) A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae. Genetics 179(3):1179-95 PMID:18562670
- Razidlo DF and Lahue RS (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40 PMID:18321795
- Seitomer E, et al. (2008) Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium. Mol Nutr Food Res 52(11):1305-15 PMID:18496816
- Tyedmers J, et al. (2008) Prion switching in response to environmental stress. PLoS Biol 6(11):e294 PMID:19067491
- Xu H, et al. (2007) Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics 176(3):1417-29 PMID:17483413
- Yuen KW, et al. (2007) Systematic genome instability screens in yeast and their potential relevance to cancer. Proc Natl Acad Sci U S A 104(10):3925-30 PMID:17360454
- Daniel JA, et al. (2006) Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics 172(1):53-65 PMID:16157669
- Gambus A, et al. (2006) GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol 8(4):358-66 PMID:16531994
- Mohanty BK, et al. (2006) The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 103(4):897-902 PMID:16418273
- Redon C, et al. (2006) Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage. Genetics 172(1):67-76 PMID:16219777
- Calzada A, et al. (2005) Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev 19(16):1905-19 PMID:16103218
- Nedelcheva MN, et al. (2005) Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol 347(3):509-21 PMID:15755447
- Coluccio A, et al. (2004) Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae. Eukaryot Cell 3(6):1464-75 PMID:15590821
- Mayer ML, et al. (2004) Identification of protein complexes required for efficient sister chromatid cohesion. Mol Biol Cell 15(4):1736-45 PMID:14742714
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Xu H, et al. (2004) Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage. Mol Cell Biol 24(16):7082-90 PMID:15282308
- Ooi SL, et al. (2003) DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray. Nat Genet 35(3):277-86 PMID:14566339
- Fleming JA, et al. (2002) Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341. Proc Natl Acad Sci U S A 99(3):1461-6 PMID:11830665
- Rabitsch KP, et al. (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9 PMID:11470404
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Ahmad S, et al. (2025) A conserved thumb domain insertion in DNA polymerase epsilon supports processive DNA synthesis. Nucleic Acids Res 53(5) PMID:40105244
- Baris Y, et al. (2022) Fast and efficient DNA replication with purified human proteins. Nature 606(7912):204-210 PMID:35585232
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Posse V, et al. (2021) Eukaryotic DNA replication with purified budding yeast proteins. Methods Enzymol 661:1-33 PMID:34776208
- Shyian M, et al. (2020) Fork pausing complex engages topoisomerases at the replisome. Genes Dev 34(1-2):87-98 PMID:31805522
- Ngo M, et al. (2019) A High-Throughput Assay for DNA Replication Inhibitors Based upon Multivariate Analysis of Yeast Growth Kinetics. SLAS Discov 24(6):669-681 PMID:30802412
- Bronstein A, et al. (2018) The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51. mBio 9(4) PMID:30018112
- Bastia D, et al. (2016) Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest. Proc Natl Acad Sci U S A 113(26):E3639-48 PMID:27298353
- Yan L, et al. (2015) The Role of Mms22p in DNA Damage Response in Candida albicans. G3 (Bethesda) 5(12):2567-78 PMID:26438292
- Low YS, et al. (2014) Kinetochore genes are required to fully activate secretory pathway expansion in S. cerevisiae under induced ER stress. Mol Biosyst 10(7):1790-802 PMID:24722431
- Alver B, et al. (2013) A Whole Genome Screen for Minisatellite Stability Genes in Stationary-Phase Yeast Cells. G3 (Bethesda) 3(4):741-756 PMID:23550123
- Fong CM, et al. (2013) The Saccharomyces cerevisiae F-box protein Dia2 is a mediator of S-phase checkpoint recovery from DNA damage. Genetics 193(2):483-99 PMID:23172854
- De Piccoli G, et al. (2012) Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol Cell 45(5):696-704 PMID:22325992
- Kilkenny ML, et al. (2012) A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome. J Biol Chem 287(28):23740-7 PMID:22593576
- Lai MS, et al. (2012) Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc1. Biochem Biophys Res Commun 427(3):682-6 PMID:23036200
- McLellan JL, et al. (2012) Synthetic lethality of cohesins with PARPs and replication fork mediators. PLoS Genet 8(3):e1002574 PMID:22412391
- Roberts SA, et al. (2012) Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. Mol Cell 46(4):424-35 PMID:22607975
- Tripathi K, et al. (2012) Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. FEMS Yeast Res 12(8):949-57 PMID:22909099
- Zhang Y, et al. (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65 PMID:22959270
- van Deursen F, et al. (2012) Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation. EMBO J 31(9):2195-206 PMID:22433841
- Jung PP, et al. (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12:331 PMID:21711526
- León Ortiz AM, et al. (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17 PMID:21459050
- Li B, et al. (2011) Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions. BMC Syst Biol 5:73 PMID:21586150
- Reid RJ, et al. (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86 PMID:21173034
- Tripathi K, et al. (2011) Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics 189(2):533-47 PMID:21840863
- Bairwa NK, et al. (2010) Replication fork arrest and rDNA silencing are two independent and separable functions of the replication terminator protein Fob1 of Saccharomyces cerevisiae. J Biol Chem 285(17):12612-9 PMID:20179323
- On T, et al. (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89 PMID:20455264
- Enserink JM, et al. (2009) Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. J Cell Biol 185(3):423-37 PMID:19398760
- Gambus A, et al. (2009) A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO J 28(19):2992-3004 PMID:19661920
- Morohashi H, et al. (2009) The amino-terminal TPR domain of Dia2 tethers SCF(Dia2) to the replisome progression complex. Curr Biol 19(22):1943-9 PMID:19913425
- Scheifele LZ, et al. (2009) Retrotransposon overdose and genome integrity. Proc Natl Acad Sci U S A 106(33):13927-32 PMID:19666515
- Shishkin AA, et al. (2009) Large-scale expansions of Friedreich's ataxia GAA repeats in yeast. Mol Cell 35(1):82-92 PMID:19595718
- Tanaka H, et al. (2009) Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts. Genes Cells 14(8):949-63 PMID:19622120
- Dixon SJ, et al. (2008) Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A 105(43):16653-8 PMID:18931302
- Gotter AL, et al. (2007) Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors. J Mol Biol 366(1):36-52 PMID:17141802
- Hanna M, et al. (2007) Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork. Mutat Res 625(1-2):164-76 PMID:17681555
- St Onge RP, et al. (2007) Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. Nat Genet 39(2):199-206 PMID:17206143
- Tronnersjö S, et al. (2007) The jmjN and jmjC domains of the yeast zinc finger protein Gis1 interact with 19 proteins involved in transcription, sumoylation and DNA repair. Mol Genet Genomics 277(1):57-70 PMID:17043893
- Tsolou A and Lydall D (2007) Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1. DNA Repair (Amst) 6(11):1607-17 PMID:17618841
- Blake D, et al. (2006) The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae. Genetics 174(4):1709-27 PMID:16751663
- Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 PMID:16487579
- Titz B, et al. (2006) Transcriptional activators in yeast. Nucleic Acids Res 34(3):955-67 PMID:16464826
- Archambault V, et al. (2005) Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol Cell Biol 25(15):6707-21 PMID:16024805
- Chang M, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33 PMID:15889139
- Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 PMID:16155567
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
- Lombardía LJ, et al. (2002) Genome-wide analysis of yeast transcription upon calcium shortage. Cell Calcium 32(2):83-91 PMID:12161108
- Tong AH, et al. (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-8 PMID:11743205
Reviews
No reviews curated.
Download References (.nbib)
- Branzei D, et al. (2024) The multifaceted roles of the Ctf4 replisome hub in the maintenance of genome integrity. DNA Repair (Amst) 142:103742 PMID:39137555
- D'Alfonso A, et al. (2024) rDNA transcription, replication and stability in Saccharomyces cerevisiae. Semin Cell Dev Biol 159-160:1-9 PMID:38244478
- Choudhary K and Kupiec M (2023) The cohesin complex of yeasts: sister chromatid cohesion and beyond. FEMS Microbiol Rev 47(1) PMID:36370456
- González-Garrido C and Prado F (2023) Novel insights into the roles of Cdc7 in response to replication stress. FEBS J 290(12):3076-3088 PMID:35398961
- Pellegrini L (2023) The CMG DNA helicase and the core replisome. Curr Opin Struct Biol 81:102612 PMID:37244171
- Sasaki M and Kobayashi T (2023) Regulatory processes that maintain or alter ribosomal DNA stability during the repair of programmed DNA double-strand breaks. Genes Genet Syst 98(3):103-119 PMID:35922917
- Wilkinson EM, et al. (2022) Observing protein dynamics during DNA-lesion bypass by the replisome. Front Mol Biosci 9:968424 PMID:36213113
- Arbel M, et al. (2021) PCNA Loaders and Unloaders-One Ring That Rules Them All. Genes (Basel) 12(11) PMID:34828416
- van Schie JJM and de Lange J (2021) The Interplay of Cohesin and the Replisome at Processive and Stressed DNA Replication Forks. Cells 10(12) PMID:34943967
- Giannattasio M and Branzei D (2019) DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae. Genes (Basel) 10(2) PMID:30795600
- Lawrimore CJ and Bloom K (2019) Common Features of the Pericentromere and Nucleolus. Genes (Basel) 10(12) PMID:31835574
- Moriel-Carretero M, et al. (2019) DDR Inc., one business, two associates. Curr Genet 65(2):445-451 PMID:30467717
- Li H and O'Donnell ME (2018) The Eukaryotic CMG Helicase at the Replication Fork: Emerging Architecture Reveals an Unexpected Mechanism. Bioessays 40(3) PMID:29405332
- Pardo B, et al. (2017) Signaling pathways of replication stress in yeast. FEMS Yeast Res 17(2) PMID:27915243
- Bell SP and Labib K (2016) Chromosome Duplication in Saccharomyces cerevisiae. Genetics 203(3):1027-67 PMID:27384026
- Bastia D and Zaman S (2014) Mechanism and physiological significance of programmed replication termination. Semin Cell Dev Biol 30:165-73 PMID:24811316
- Edenberg ER, et al. (2014) Polymerase stalling during replication, transcription and translation. Curr Biol 24(10):R445-52 PMID:24845677
- Marston AL (2014) Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms. Genetics 196(1):31-63 PMID:24395824
- Singh J (2014) Role of DNA replication in establishment and propagation of epigenetic states of chromatin. Semin Cell Dev Biol 30:131-43 PMID:24794003
- Errico A and Costanzo V (2010) Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns. EMBO Rep 11(4):270-8 PMID:20203697
- Glynn M, et al. (2010) Centromeres: assembling and propagating epigenetic function. Subcell Biochem 50:223-49 PMID:20012585
- McFarlane RJ, et al. (2010) The many facets of the Tim-Tipin protein families' roles in chromosome biology. Cell Cycle 9(4):700-5 PMID:20139726
- Davidson MB and Brown GW (2009) Dissecting the DNA damage response using functional genomics approaches in S. cerevisiae. DNA Repair (Amst) 8(9):1110-7 PMID:19464964
- Friedel AM, et al. (2009) ATR/Mec1: coordinating fork stability and repair. Curr Opin Cell Biol 21(2):237-44 PMID:19230642
- Kaplan DL and Bastia D (2009) Mechanisms of polar arrest of a replication fork. Mol Microbiol 72(2):279-85 PMID:19298368
- Schleker T, et al. (2009) Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks. DNA Repair (Amst) 8(9):1089-100 PMID:19482523
- Fu Y, et al. (2008) DNA damage-induced gene expression in Saccharomyces cerevisiae. FEMS Microbiol Rev 32(6):908-26 PMID:18616603
- Holloman WK, et al. (2008) The homologous recombination system of Ustilago maydis. Fungal Genet Biol 45 Suppl 1(Suppl 1):S31-9 PMID:18502156
- Sclafani RA and Holzen TM (2007) Cell cycle regulation of DNA replication. Annu Rev Genet 41:237-80 PMID:17630848
- Nedelcheva-Veleva MN, et al. (2006) Coordination of DNA synthesis and replicative unwinding by the S-phase checkpoint pathways. Nucleic Acids Res 34(15):4138-46 PMID:16935878
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 PMID:22842922
- Bando M, et al. (2009) Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284(49):34355-65 PMID:19819872
- Fernius J and Marston AL (2009) Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. PLoS Genet 5(9):e1000629 PMID:19730685
- Razidlo DF and Lahue RS (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40 PMID:18321795
- Xu H, et al. (2007) Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics 176(3):1417-29 PMID:17483413
- Mohanty BK, et al. (2006) The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 103(4):897-902 PMID:16418273
- Redon C, et al. (2006) Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage. Genetics 172(1):67-76 PMID:16219777
- Calzada A, et al. (2005) Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev 19(16):1905-19 PMID:16103218
- Mayer ML, et al. (2004) Identification of protein complexes required for efficient sister chromatid cohesion. Mol Biol Cell 15(4):1736-45 PMID:14742714
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
- Rabitsch KP, et al. (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9 PMID:11470404
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Gordon MR, et al. (2023) Suppression of chromosome instability by targeting a DNA helicase in budding yeast. Mol Biol Cell 34(1):ar3 PMID:36350688
- Shrestha S, et al. (2023) Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors. Chromosoma 132(2):117-135 PMID:37166686
- Sulaiman AA, et al. (2023) Mft1, identified from a genome-wide screen of the yeast haploid mutants, mediates cell cycle arrest to counteract quinoxaline-induced toxicity. Front Genet 14:1296383 PMID:38283148
- Matmati N, et al. (2020) Yeast Sphingolipid Phospholipase Gene ISC1 Regulates the Spindle Checkpoint by a CDC55-Dependent Mechanism. Mol Cell Biol 40(12) PMID:32205408
- Novarina D, et al. (2020) A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae. G3 (Bethesda) 10(6):1853-1867 PMID:32265288
- Borges V, et al. (2013) An Eco1-independent sister chromatid cohesion establishment pathway in S. cerevisiae. Chromosoma 122(1-2):121-34 PMID:23334284
- Andersen MP, et al. (2008) A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae. Genetics 179(3):1179-95 PMID:18562670
- Seitomer E, et al. (2008) Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium. Mol Nutr Food Res 52(11):1305-15 PMID:18496816
- Tyedmers J, et al. (2008) Prion switching in response to environmental stress. PLoS Biol 6(11):e294 PMID:19067491
- Yuen KW, et al. (2007) Systematic genome instability screens in yeast and their potential relevance to cancer. Proc Natl Acad Sci U S A 104(10):3925-30 PMID:17360454
- Daniel JA, et al. (2006) Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics 172(1):53-65 PMID:16157669
- Redon C, et al. (2006) Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage. Genetics 172(1):67-76 PMID:16219777
- Coluccio A, et al. (2004) Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae. Eukaryot Cell 3(6):1464-75 PMID:15590821
- Fleming JA, et al. (2002) Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341. Proc Natl Acad Sci U S A 99(3):1461-6 PMID:11830665
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Gordon MR, et al. (2023) Suppression of chromosome instability by targeting a DNA helicase in budding yeast. Mol Biol Cell 34(1):ar3 PMID:36350688
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Mishra PK, et al. (2023) Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability. Mol Biol Cell 34(10):ar99 PMID:37436802
- Psakhye I, et al. (2023) PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion. Nat Struct Mol Biol 30(9):1286-1294 PMID:37592094
- Shrestha S, et al. (2023) Replisome-cohesin interactions provided by the Tof1-Csm3 and Mrc1 cohesion establishment factors. Chromosoma 132(2):117-135 PMID:37166686
- Lamb NA, et al. (2022) Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes. Genetics 221(4) PMID:35686905
- Lu PYT, et al. (2022) A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. Genetics 222(3) PMID:36066422
- Leng H, et al. (2021) FACT interacts with Set3 HDAC and fine-tunes GAL1 transcription in response to environmental stimulation. Nucleic Acids Res 49(10):5502-5519 PMID:33963860
- McClure AW and Diffley JF (2021) Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation. Elife 10 PMID:34387546
- Appanah R, et al. (2020) Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability. Cell Rep 30(7):2094-2105.e9 PMID:32075754
- Ming Sun S, et al. (2020) A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae. J Cell Sci 133(10) PMID:32299836
- Sanders E, et al. (2020) Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) 10(12):4359-4368 PMID:33115720
- Shyian M, et al. (2020) Fork pausing complex engages topoisomerases at the replisome. Genes Dev 34(1-2):87-98 PMID:31805522
- Westhorpe R, et al. (2020) Separable functions of Tof1/Timeless in intra-S-checkpoint signalling, replisome stability and DNA topological stress. Nucleic Acids Res 48(21):12169-12187 PMID:33166393
- Bryant EE, et al. (2019) Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability. Nucleic Acids Res 47(17):9144-9159 PMID:31350889
- Mukherjee PP and Labib KPM (2019) In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast. Cell Rep 28(11):2777-2783.e4 PMID:31509741
- Winczura A, et al. (2019) The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε. PLoS Genet 15(11):e1008427 PMID:31765407
- Bronstein A, et al. (2018) The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51. mBio 9(4) PMID:30018112
- Corcoles-Saez I, et al. (2018) Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis. Dev Cell 46(4):495-503.e2 PMID:30130531
- Díaz-Mejía JJ, et al. (2018) Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics. Mol Syst Biol 14(5):e7985 PMID:29807908
- Evrin C, et al. (2018) Histone H2A-H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin. EMBO J 37(19) PMID:30104407
- Kuzmin E, et al. (2018) Systematic analysis of complex genetic interactions. Science 360(6386) PMID:29674565
- Menin L, et al. (2018) Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning. EMBO Rep 19(7) PMID:29739811
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Srivatsan A, et al. (2018) The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. Nat Commun 9(1):3680 PMID:30206225
- Litwin I, et al. (2017) The LSH/HELLS homolog Irc5 contributes to cohesin association with chromatin in yeast. Nucleic Acids Res 45(11):6404-6416 PMID:28383696
- Makrantoni V, et al. (2017) A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis. G3 (Bethesda) 7(9):3203-3215 PMID:28754723
- Puddu F, et al. (2017) Chromatin determinants impart camptothecin sensitivity. EMBO Rep 18(6):1000-1012 PMID:28389464
- Buser R, et al. (2016) The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress. PLoS Genet 12(2):e1005843 PMID:26849847
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Shyian M, et al. (2016) Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication. PLoS Genet 12(11):e1006414 PMID:27820830
- Steunou AL, et al. (2016) Combined Action of Histone Reader Modules Regulates NuA4 Local Acetyltransferase Function but Not Its Recruitment on the Genome. Mol Cell Biol 36(22):2768-2781 PMID:27550811
- Styles EB, et al. (2016) Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. Cell Syst 3(3):264-277.e10 PMID:27617677
- Villa F, et al. (2016) Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase. Mol Cell 63(3):385-96 PMID:27397685
- Che J, et al. (2015) Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis. PLoS Genet 11(2):e1004990 PMID:25705897
- Dubarry M, et al. (2015) Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae. G3 (Bethesda) 5(10):2187-97 PMID:26297725
- Gallina I, et al. (2015) Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Nat Commun 6:6533 PMID:25817432
- Kershaw CJ, et al. (2015) Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p. Sci Rep 5:15518 PMID:26493364
- Maculins T, et al. (2015) Tethering of SCF(Dia2) to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase. Curr Biol 25(17):2254-9 PMID:26255844
- Mattiazzi Ušaj M, et al. (2015) Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis. Metallomics 7(9):1338-51 PMID:26067383
- Menolfi D, et al. (2015) Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance. Mol Cell 60(6):835-46 PMID:26698660
- Tsai FL, et al. (2015) Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. Mol Cell Biol 35(12):2131-43 PMID:25870112
- Leung GP, et al. (2014) Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae. G3 (Bethesda) 4(6):1059-69 PMID:24700328
- Maric M, et al. (2014) Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication. Science 346(6208):1253596 PMID:25342810
- Uzunova SD, et al. (2014) The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence. Cell Div 9:4 PMID:25379053
- Aristizabal MJ, et al. (2013) High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8. PLoS Genet 9(8):e1003758 PMID:24009531
- Borges V, et al. (2013) An Eco1-independent sister chromatid cohesion establishment pathway in S. cerevisiae. Chromosoma 122(1-2):121-34 PMID:23334284
- Foltman M, et al. (2013) Eukaryotic replisome components cooperate to process histones during chromosome replication. Cell Rep 3(3):892-904 PMID:23499444
- Fong CM, et al. (2013) The Saccharomyces cerevisiae F-box protein Dia2 is a mediator of S-phase checkpoint recovery from DNA damage. Genetics 193(2):483-99 PMID:23172854
- LeClere AR, et al. (2013) The role of CSM3, MRC1, and TOF1 in minisatellite stability and large loop DNA repair during meiosis in yeast. Fungal Genet Biol 50:33-43 PMID:23165348
- Nguyen HD, et al. (2013) Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression. PLoS One 8(6):e66379 PMID:23824283
- Sengupta S, et al. (2013) Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Curr Biol 23(7):543-52 PMID:23499531
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- De Piccoli G, et al. (2012) Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol Cell 45(5):696-704 PMID:22325992
- Kilkenny ML, et al. (2012) A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome. J Biol Chem 287(28):23740-7 PMID:22593576
- Lai MS, et al. (2012) Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc1. Biochem Biophys Res Commun 427(3):682-6 PMID:23036200
- McLellan JL, et al. (2012) Synthetic lethality of cohesins with PARPs and replication fork mediators. PLoS Genet 8(3):e1002574 PMID:22412391
- Tripathi K, et al. (2012) Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. FEMS Yeast Res 12(8):949-57 PMID:22909099
- van Deursen F, et al. (2012) Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation. EMBO J 31(9):2195-206 PMID:22433841
- Addinall SG, et al. (2011) Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. PLoS Genet 7(4):e1001362 PMID:21490951
- Bairwa NK, et al. (2011) The intra-S phase checkpoint protein Tof1 collaborates with the helicase Rrm3 and the F-box protein Dia2 to maintain genome stability in Saccharomyces cerevisiae. J Biol Chem 286(4):2445-54 PMID:21087929
- Boettner DR, et al. (2011) Clathrin light chain directs endocytosis by influencing the binding of the yeast Hip1R homologue, Sla2, to F-actin. Mol Biol Cell 22(19):3699-714 PMID:21849475
- Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78 PMID:21460040
- León Ortiz AM, et al. (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17 PMID:21459050
- Reid RJ, et al. (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86 PMID:21173034
- Scherrer T, et al. (2011) Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Genome Biol 12(1):R3 PMID:21232131
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Tripathi K, et al. (2011) Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics 189(2):533-47 PMID:21840863
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Moriel-Carretero M and Aguilera A (2010) A postincision-deficient TFIIH causes replication fork breakage and uncovers alternative Rad51- or Pol32-mediated restart mechanisms. Mol Cell 37(5):690-701 PMID:20227372
- Bando M, et al. (2009) Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284(49):34355-65 PMID:19819872
- Enserink JM, et al. (2009) Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. J Cell Biol 185(3):423-37 PMID:19398760
- Fernius J and Marston AL (2009) Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. PLoS Genet 5(9):e1000629 PMID:19730685
- Fiedler D, et al. (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63 PMID:19269370
- Gambus A, et al. (2009) A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO J 28(19):2992-3004 PMID:19661920
- Komata M, et al. (2009) The direct binding of Mrc1, a checkpoint mediator, to Mcm6, a replication helicase, is essential for the replication checkpoint against methyl methanesulfonate-induced stress. Mol Cell Biol 29(18):5008-19 PMID:19620285
- Mohanty BK, et al. (2009) Contrasting roles of checkpoint proteins as recombination modulators at Fob1-Ter complexes with or without fork arrest. Eukaryot Cell 8(4):487-95 PMID:19234097
- Morohashi H, et al. (2009) The amino-terminal TPR domain of Dia2 tethers SCF(Dia2) to the replisome progression complex. Curr Biol 19(22):1943-9 PMID:19913425
- Waples WG, et al. (2009) Putting the brake on FEAR: Tof2 promotes the biphasic release of Cdc14 phosphatase during mitotic exit. Mol Biol Cell 20(1):245-55 PMID:18923139
- Brett CL, et al. (2008) Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. J Cell Biol 182(6):1141-51 PMID:18809726
- Dixon SJ, et al. (2008) Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A 105(43):16653-8 PMID:18931302
- Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74 PMID:18676811
- Mitchell L, et al. (2008) Functional dissection of the NuA4 histone acetyltransferase reveals its role as a genetic hub and that Eaf1 is essential for complex integrity. Mol Cell Biol 28(7):2244-56 PMID:18212056
- Yu H, et al. (2008) High-quality binary protein interaction map of the yeast interactome network. Science 322(5898):104-10 PMID:18719252
- Collins SR, et al. (2007) Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature 446(7137):806-10 PMID:17314980
- Hanna M, et al. (2007) Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork. Mutat Res 625(1-2):164-76 PMID:17681555
- St Onge RP, et al. (2007) Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions. Nat Genet 39(2):199-206 PMID:17206143
- Thaminy S, et al. (2007) Hst3 is regulated by Mec1-dependent proteolysis and controls the S phase checkpoint and sister chromatid cohesion by deacetylating histone H3 at lysine 56. J Biol Chem 282(52):37805-14 PMID:17977840
- Tronnersjö S, et al. (2007) The jmjN and jmjC domains of the yeast zinc finger protein Gis1 interact with 19 proteins involved in transcription, sumoylation and DNA repair. Mol Genet Genomics 277(1):57-70 PMID:17043893
- Xu H, et al. (2007) Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics 176(3):1417-29 PMID:17483413
- Daniel JA, et al. (2006) Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics 172(1):53-65 PMID:16157669
- Gambus A, et al. (2006) GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol 8(4):358-66 PMID:16531994
- Keogh MC, et al. (2006) A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature 439(7075):497-501 PMID:16299494
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 PMID:16487579
- Redon C, et al. (2006) Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage. Genetics 172(1):67-76 PMID:16219777
- Archambault V, et al. (2005) Disruption of mechanisms that prevent rereplication triggers a DNA damage response. Mol Cell Biol 25(15):6707-21 PMID:16024805
- Budd ME, et al. (2005) A network of multi-tasking proteins at the DNA replication fork preserves genome stability. PLoS Genet 1(6):e61 PMID:16327883
- Chang M, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33 PMID:15889139
- Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 PMID:16155567
- Nedelcheva MN, et al. (2005) Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol 347(3):509-21 PMID:15755447
- Ptacek J, et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84 PMID:16319894
- Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1:2005.0026 PMID:16729061
- Mayer ML, et al. (2004) Identification of protein complexes required for efficient sister chromatid cohesion. Mol Biol Cell 15(4):1736-45 PMID:14742714
- Pan X, et al. (2004) A robust toolkit for functional profiling of the yeast genome. Mol Cell 16(3):487-96 PMID:15525520
- Suter B, et al. (2004) The origin recognition complex links replication, sister chromatid cohesion and transcriptional silencing in Saccharomyces cerevisiae. Genetics 167(2):579-91 PMID:15238513
- Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 PMID:14764870
- Xu H, et al. (2004) Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage. Mol Cell Biol 24(16):7082-90 PMID:15282308
- Ito T, et al. (2001) A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A 98(8):4569-74 PMID:11283351
- Tong AH, et al. (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science 294(5550):2364-8 PMID:11743205
- Uetz P, et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature 403(6770):623-7 PMID:10688190
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Sulaiman AA, et al. (2023) Mft1, identified from a genome-wide screen of the yeast haploid mutants, mediates cell cycle arrest to counteract quinoxaline-induced toxicity. Front Genet 14:1296383 PMID:38283148
- Yu R, et al. (2021) Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism. Nat Commun 12(1):1981 PMID:33790287
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Putnam CD, et al. (2016) A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers. Nat Commun 7:11256 PMID:27071721
- Hoepfner D, et al. (2014) High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions. Microbiol Res 169(2-3):107-20 PMID:24360837
- Peyroche G, et al. (2012) Sodium selenide toxicity is mediated by O2-dependent DNA breaks. PLoS One 7(5):e36343 PMID:22586468
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6:451 PMID:21179023
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Hu Z, et al. (2007) Genetic reconstruction of a functional transcriptional regulatory network. Nat Genet 39(5):683-7 PMID:17417638
- Brown JA, et al. (2006) Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol Syst Biol 2:2006.0001 PMID:16738548
- Butcher RA, et al. (2006) Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. Nat Chem Biol 2(2):103-9 PMID:16415861
- MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics 7:113 PMID:16522208
- Irwin B, et al. (2005) Retroviruses and yeast retrotransposons use overlapping sets of host genes. Genome Res 15(5):641-54 PMID:15837808
- Lee W, et al. (2005) Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. PLoS Genet 1(2):e24 PMID:16121259
- Parsons AB, et al. (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9 PMID:14661025
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Rabitsch KP, et al. (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9 PMID:11470404