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CCS1 / YMR038C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

LYS7 5 , CCS 5
Protein Product
copper chaperone CCS1
Feature Type
ORF , Verified
Copper chaperone for superoxide dismutase Sod1p; involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within N-terminus is involved in insertion of copper into Sod1p under conditions of copper deprivation; required for regulation of yeast copper genes in response to DNA-damaging agents; protein abundance increases in response to DNA replication stress; human homolog CCS can complement yeast ccs1 null mutant 2 3 4 5 6 7