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HOF1 / YMR032W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

CYK2 2
Protein Product
formin-binding protein HOF1
Feature Type
ORF , Verified
F-BAR protein that regulates actin cytoskeleton organization; binds and bundles actin filaments, linking them to septins; required for cytokinesis, actin cable organization, and secretory vesicle trafficking; regulates actomyosin ring dynamics and septin localization; N-term. half controls cell size and actin cable levels, while the C-term. half controls actin cable organization, inhibiting Bnr1p-mediated actin nucleation; forms axial striations/pillars at the bud neck; phosphorylated by Dbf2p 1 2 3 4 5 6 7 8