Phenotype Help

MSS1 / YMR023C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

18 entries for 15 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: mss1-Δ
S288C alpha-amino acidDetails: Significantly altered free amino acid profile (X^2- test p < 0.01), showing 1 simultaneous amino acid change (Z-test, adjusted p < 0.01)
Mülleder M, et al. (2016) PMID:27693354
chemical compound accumulation: increased
systematic mutation setnull
Allele: mss1-Δ
S288C tyrosineMülleder M, et al. (2016) PMID:27693354
chronological lifespan: decreased
competitive growth

competitive survival of mixed stationary phase co-cultures

null
Allele: mss1-Δ
S288CGaray E, et al. (2014) PMID:24586198
colony sectoring: increased
heterozygous diploid, systematic mutation setnull
Allele: mss1-Δ
S288CAssay: quantitative chromosome transmission fidelity (qCTF) assay
Details: >1.5 fold increase in mini-chromosome loss relative to wt, indicative of chromosome instability (CIN)
Zhu J, et al. (2015) PMID:25823586
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: mss1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.991
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: mss1-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: mss1-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
desiccation resistance: decreased
homozygous diploid, systematic mutation setnull
Allele: mss1-Δ
S288CTreatment: pooled mutants subject to three cycles of growth to post-diauxic phase followed by desiccation and regrowth
Details: 2-fold or greater decreased survival after the treatment
Ratnakumar S, et al. (2011) PMID:20963216
endocytosis: decreased
systematic mutation setnull
Allele: mss1-Δ
S288CDetails: defective internalization of a chimeric Snc1p reporter, GFP-Snc1-Suc2
Burston HE, et al. (2009) PMID:19506040
haploproficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: mss1-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: 0.0096
Pir P, et al. (2012) PMID:22244311
Showing 1 to 10 of 18 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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