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VPS9 / YML097C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

VPL31 10 , VPT9 1
Protein Product
guanine nucleotide exchange factor VPS9
Feature Type
ORF , Verified
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain 3 4 5 6 7 8 9