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PIF1 / YML061C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
TST1
Protein Product
DNA helicase PIF1
Feature Type
ORF , Verified
Description
DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells 1 3 4 5 6 7 8 9 10 11
EC Number
3.6.4.12

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