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PIF1 / YML061C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
DNA helicase PIF1
Feature Type
ORF , Verified
DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; involved in crossover recombination; works with Hrq1p to maintain telomere length homeostasis; translation from different start sites produces mitochondrial (DNA repair and recombination) and nuclear (catalytic inhibitor of telomerase) forms; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells 1 3 4 5 6 7 8 9 10 11 12
EC Number