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YAP1 / YML007W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
PAR1 35 , SNQ3 32 , PDR4 22
Protein Product
DNA-binding transcription factor YAP1
Feature Type
ORF , Verified
Description
Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication 2 3 4 5 6 7 8
Paralog
CAD1 7

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