Phenotype Help

ECM19 / YLR390W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant is sensitive to Calcofluor White, hygromycin B, and treatment with zymolyase, indicating cell wall defects; in systematic studies mutants are sensitive to pentachlorophenol

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

14 entries for 10 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
bud morphology: abnormal
classical geneticsunspecifiedOtherDetails: large drooping buds with elongated bud necks
Lussier M, et al. (1997) PMID:9335584
cell size: increased
classical geneticsunspecifiedOtherDetails: up to four times greater than wild type cells
Lussier M, et al. (1997) PMID:9335584
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: ecm19-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.989
Breslow DK, et al. (2008) PMID:18622397
killer toxin resistance: decreased
classical geneticsunspecifiedOtherDetails: K1 killer toxin hypersensitive
Lussier M, et al. (1997) PMID:9335584
metal resistance: decreased
homozygous diploid, systematic mutation set null
Allele: ecm19-Δ
S288C2.4 mM aluminium(3+)Treatment: aluminium sulfate, 2.4 mM
Schulze Y, et al. (2023) PMID:37193668
metal resistance: decreased
homozygous diploid, systematic mutation set null
Allele: ecm19-Δ
S288C2.6 mM indium(3+)Treatment: indium chloride, 2.6 mM
Schulze Y, et al. (2023) PMID:37193668
resistance to chemicals: decreased
large-scale surveyunspecifiedOther Calcofluor WhiteDetails: hypersensitive
Lussier M, et al. (1997) PMID:9335584
resistance to chemicals: decreased
classical geneticsnull
Allele: ecm19-Δ
Other Calcofluor WhiteDetails: hypersensitive
Lussier M, et al. (1997) PMID:9335584
resistance to chemicals: decreased
classical geneticsunspecifiedOther50-100 mg/ml hygromycin BDetails: hypersensitive
Lussier M, et al. (1997) PMID:9335584
resistance to chemicals: decreased
systematic mutation setnull
Allele: ecm19-Δ
S288C0.156 mM pentachlorophenolYadav V, et al. (2011) PMID:20967895
Showing 1 to 10 of 14 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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