Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.
130 entries for 31 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
---|---|---|---|---|---|---|
axial budding pattern: decreased | homozygous diploid | null Allele: chs5-Δ | S288C | Details: null mutant buds randomly, rather than in a bipolar pattern, as observed in wt diploids | Trautwein M, et al. (2006) PMID:16498409 | |
cell fusion: decreased | classical genetics | null Allele: chs5-Δ | Other | Treatment: mated to wild type cells Details: defective in cell fusion with increased prezygote formation, in which cell walls fuse but membranes do not | Dorer R, et al. (1997) PMID:9135999 | |
chemical compound accumulation: decreased | homozygous diploid | null Allele: chs5-Δ | S288C | tellurium atom, 0.1 mM potassium tellurite | Ottosson LG, et al. (2010) PMID:20675578 | |
chemical compound accumulation: decreased | homozygous diploid, systematic mutation set | null Allele: chs5-Δ | S288C | rubidium(1+) | Details: Rb+ influx is a measure of K+ influx | Fell GL, et al. (2011) PMID:22384317 |
chemical compound excretion: increased | homozygous diploid, systematic mutation set quantification of extracellular glutathione at stationary phase | null Allele: chs5-Δ | S288C | glutathione | Treatment: SD medium Details: Fold elevation of glutathione excretion: 5 | Perrone GG, et al. (2005) PMID:15509654 |
chitin deposition: decreased | systematic mutation set | null Allele: chs5-Δ | S288C | Details: fluorescent Calcofluor white binding | Lam KK, et al. (2006) PMID:16818716 | |
chitin deposition: decreased | classical genetics | null Allele: chs5-Δ | Other | Details: chitin content is 25% of wild-type | Santos B, et al. (1997) PMID:9111317 | |
chitin deposition: decreased | classical genetics | null Allele: chs5-Δ | S288C | Details: decreased calcofluor white staining of the cell wall | Trautwein M, et al. (2006) PMID:16498409 | |
chitin deposition: decreased | systematic mutation set | null Allele: chs5-Δ | S288C | Details: Chitin level (nmole GlcNAc/mg dry weight): 3.2 | Lesage G, et al. (2005) PMID:15715908 | |
competitive fitness: decreased | systematic mutation set fitness profiling after 20 generations | null Allele: chs5-Δ | S288C | 1 M sodium chloride | Giaever G, et al. (2002) PMID:12140549 |
This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).
Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
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