Literature Help
VPS34 / YLR240W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
- Unique References
- 436
- Aliases
-
STT8
34
35
,
VPS7
36
,
END12
16
,
PEP15
37
,
VPL7
38
,
VPT29
1
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Mirisola MG and Longo VD (2024) Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast. Biomed J 47(2):100694 PMID:38154617
- Suda K, et al. (2024) Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts. Nat Aging 4(3):319-335 PMID:38388781
- Hitomi K, et al. (2023) The Atg1 complex, Atg9, and Vac8 recruit PI3K complex I to the pre-autophagosomal structure. J Cell Biol 222(8) PMID:37436710
- Huda M, et al. (2023) The signalling lipid PI3,5P2 is essential for timely mitotic exit. Open Biol 13(9):230125 PMID:37751887
- Lee Y, et al. (2023) Atg1-dependent phosphorylation of Vps34 is required for dynamic regulation of the phagophore assembly site and autophagy in Saccharomyces cerevisiae. Autophagy 19(9):2428-2442 PMID:36803233
- Couvillion M, et al. (2022) Transcription elongation is finely tuned by dozens of regulatory factors. Elife 11 PMID:35575476
- Laidlaw KME, et al. (2022) Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation. Mol Biol Cell 33(4):ar31 PMID:35080991
- Tasnin MN, et al. (2022) The PI3 Kinase Complex II-PI3P-Vps27 Axis on Vacuolar Membranes is Critical for Microautophagy Induction and Nutrient Stress Adaptation. J Mol Biol 434(2):167360 PMID:34798133
- Zeng L, et al. (2022) Transcriptomic analysis of formic acid stress response in Saccharomyces cerevisiae. World J Microbiol Biotechnol 38(2):34 PMID:34989900
- Zhao L, et al. (2022) Vps21 Directs the PI3K-PI(3)P-Atg21-Atg16 Module to Phagophores via Vps8 for Autophagy. Int J Mol Sci 23(17) PMID:36076954
- Hepowit NL, et al. (2021) Enhancing lifespan of budding yeast by pharmacological lowering of amino acid pools. Aging (Albany NY) 13(6):7846-7871 PMID:33744865
- Jin X, et al. (2021) Retromer Complex and PI3K Complex II-Related Genes Mediate the Yeast (Saccharomyces cerevisiae) Sodium Metabisulfite Resistance Response. Cells 10(12) PMID:34944020
- Kim B, et al. (2021) The trehalose-6-phosphate phosphatase Tps2 regulates ATG8 transcription and autophagy in Saccharomyces cerevisiae. Autophagy 17(4):1013-1027 PMID:32240040
- Maiti A, et al. (2021) Cigarette smoke affects ESCRT-mediated vacuolar activity in Saccharomyces cerevisiae. Toxicol Lett 338:97-104 PMID:33309995
- Steinfeld N, et al. (2021) Elevating PI3P drives select downstream membrane trafficking pathways. Mol Biol Cell 32(2):143-156 PMID:33237833
- Uppala JK, et al. (2021) Vps34 and TOR Kinases Coordinate HAC1 mRNA Translation in the Presence or Absence of Ire1-Dependent Splicing. Mol Cell Biol 41(7):e0066220 PMID:33972394
- Rangarajan N, et al. (2020) Potassium starvation induces autophagy in yeast. J Biol Chem 295(41):14189-14202 PMID:32788210
- Kuroda K, et al. (2019) Critical Roles of the Pentose Phosphate Pathway and GLN3 in Isobutanol-Specific Tolerance in Yeast. Cell Syst 9(6):534-547.e5 PMID:31734159
- Plummer JD and Johnson JE (2019) Extension of Cellular Lifespan by Methionine Restriction Involves Alterations in Central Carbon Metabolism and Is Mitophagy-Dependent. Front Cell Dev Biol 7:301 PMID:31850341
- Rangarajan N, et al. (2019) Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. J Biol Chem 294(40):14717-14731 PMID:31399514
- Wang Z, et al. (2019) QTL analysis reveals genomic variants linked to high-temperature fermentation performance in the industrial yeast. Biotechnol Biofuels 12:59 PMID:30923567
- Ejzykowicz DE, et al. (2017) Hygromycin B hypersensitive (hhy) mutants implicate an intact trans-Golgi and late endosome interface in efficient Tor1 vacuolar localization and TORC1 function. Curr Genet 63(3):531-551 PMID:27812735
- Golla U, et al. (2017) A systematic assessment of chemical, genetic, and epigenetic factors influencing the activity of anticancer drug KP1019 (FFC14A). Oncotarget 8(58):98426-98454 PMID:29228701
- Gopaldass N, et al. (2017) Membrane scission driven by the PROPPIN Atg18. EMBO J 36(22):3274-3291 PMID:29030482
- Kruzel-Davila E, et al. (2017) APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes. J Am Soc Nephrol 28(4):1117-1130 PMID:27864431
- Segovia R, et al. (2017) Genome-wide bisulfite sensitivity profiling of yeast suggests bisulfite inhibits transcription. Mutat Res Genet Toxicol Environ Mutagen 821:13-19 PMID:28735739
- Stjepanovic G, et al. (2017) Vps34 Kinase Domain Dynamics Regulate the Autophagic PI 3-Kinase Complex. Mol Cell 67(3):528-534.e3 PMID:28757208
- Zhu L, et al. (2017) ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins. Elife 6 PMID:28661397
- Zhu X, et al. (2017) A genetic screen in combination with biochemical analysis in Saccharomyces cerevisiae indicates that phenazine-1-carboxylic acid is harmful to vesicular trafficking and autophagy. Sci Rep 7(1):1967 PMID:28512289
- Ohashi Y, et al. (2016) Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. Autophagy 12(11):2129-2144 PMID:27630019
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Adhikari H and Cullen PJ (2015) Role of phosphatidylinositol phosphate signaling in the regulation of the filamentous-growth mitogen-activated protein kinase pathway. Eukaryot Cell 14(4):427-40 PMID:25724886
- Rostislavleva K, et al. (2015) Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes. Science 350(6257):aac7365 PMID:26450213
- Cruz-Garcia D, et al. (2014) Remodeling of secretory compartments creates CUPS during nutrient starvation. J Cell Biol 207(6):695-703 PMID:25512390
- Lawrence G, et al. (2014) Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3. Mol Biol Cell 25(10):1608-19 PMID:24623720
- Ueno K, et al. (2014) V-ATPase-dependent luminal acidification is required for endocytic recycling of a yeast cell wall stress sensor, Wsc1p. Biochem Biophys Res Commun 443(2):549-55 PMID:24326069
- van Zutphen T, et al. (2014) Lipid droplet autophagy in the yeast Saccharomyces cerevisiae. Mol Biol Cell 25(2):290-301 PMID:24258026
- Araki Y, et al. (2013) Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity. J Cell Biol 203(2):299-313 PMID:24165940
- Gaur NA, et al. (2013) Vps factors are required for efficient transcription elongation in budding yeast. Genetics 193(3):829-51 PMID:23335340
- Graef M, et al. (2013) ER exit sites are physical and functional core autophagosome biogenesis components. Mol Biol Cell 24(18):2918-31 PMID:23904270
- Alex D, et al. (2012) Amino acid-derived 1,2-benzisothiazolinone derivatives as novel small-molecule antifungal inhibitors: identification of potential genetic targets. Antimicrob Agents Chemother 56(9):4630-9 PMID:22687516
- Alibhoy AA, et al. (2012) Vps34p is required for the decline of extracellular fructose-1,6-bisphosphatase in the vacuole import and degradation pathway. J Biol Chem 287(39):33080-93 PMID:22833678
- Bridges D, et al. (2012) Rab5 proteins regulate activation and localization of target of rapamycin complex 1. J Biol Chem 287(25):20913-21 PMID:22547071
- Chicanne G, et al. (2012) A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples. Biochem J 447(1):17-23 PMID:22830526
- Galluzzi L, et al. (2012) Independent transcriptional reprogramming and apoptosis induction by cisplatin. Cell Cycle 11(18):3472-80 PMID:22918244
- Mániková D, et al. (2012) Selenium toxicity toward yeast as assessed by microarray analysis and deletion mutant library screen: a role for DNA repair. Chem Res Toxicol 25(8):1598-608 PMID:22747191
- Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30 PMID:22177309
- Zieger M and Mayer A (2012) Yeast vacuoles fragment in an asymmetrical two-phase process with distinct protein requirements. Mol Biol Cell 23(17):3438-49 PMID:22787281
- Bruns C, et al. (2011) Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion. J Cell Biol 195(6):979-92 PMID:22144692
- Burtner CR, et al. (2011) A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle 10(9):1385-96 PMID:21447998
- Grunau S, et al. (2011) The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae. Biochem J 434(1):161-70 PMID:21121900
- Han BK and Emr SD (2011) Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1. Genes Dev 25(9):984-95 PMID:21536737
- Banuelos MG, et al. (2010) Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae. Curr Genet 56(2):121-37 PMID:20043226
- Huber A, et al. (2009) Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev 23(16):1929-43 PMID:19684113
- Wiederhold E, et al. (2009) The yeast vacuolar membrane proteome. Mol Cell Proteomics 8(2):380-92 PMID:19001347
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Obara K, et al. (2008) The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J Biol Chem 283(35):23972-80 PMID:18586673
- Obara K, et al. (2008) Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae. Genes Cells 13(6):537-47 PMID:18533003
- Rutledge RM, et al. (2008) Pdr5-mediated multidrug resistance requires the CPY-vacuolar sorting protein Vps3: are xenobiotic compounds routed from the vacuole to plasma membrane transporters for efflux? Mol Genet Genomics 279(6):573-83 PMID:18327613
- Schoijet AC, et al. (2008) A Trypanosoma cruzi phosphatidylinositol 3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis. J Biol Chem 283(46):31541-50 PMID:18801733
- Zhang F, et al. (2008) Disrupting vesicular trafficking at the endosome attenuates transcriptional activation by Gcn4. Mol Cell Biol 28(22):6796-818 PMID:18794364
- Pagani MA, et al. (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol Microbiol 65(2):521-37 PMID:17630978
- Obara K, et al. (2006) Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell 17(4):1527-39 PMID:16421251
- Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 PMID:16839886
- Alaimo PJ, et al. (2005) Targeting the gatekeeper residue in phosphoinositide 3-kinases. Bioorg Med Chem 13(8):2825-36 PMID:15781393
- Parrish WR, et al. (2005) PtdIns(3)P accumulation in triple lipid-phosphatase-deletion mutants triggers lethal hyperactivation of the Rho1p/Pkc1p cell-integrity MAP kinase pathway. J Cell Sci 118(Pt 23):5589-601 PMID:16306222
- Rog O, et al. (2005) The yeast VPS genes affect telomere length regulation. Curr Genet 47(1):18-28 PMID:15551135
- Reggiori F, et al. (2004) Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Mol Biol Cell 15(5):2189-204 PMID:15004240
- Strømhaug PE, et al. (2004) Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Mol Biol Cell 15(8):3553-66 PMID:15155809
- Katzmann DJ, et al. (2003) Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol 162(3):413-23 PMID:12900393
- Budovskaya YV, et al. (2002) The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase. J Biol Chem 277(1):287-94 PMID:11689570
- Burda P, et al. (2002) Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase. J Cell Sci 115(Pt 20):3889-900 PMID:12244127
- Gurunathan S, et al. (2002) Dynamin and clathrin are required for the biogenesis of a distinct class of secretory vesicles in yeast. EMBO J 21(4):602-14 PMID:11847108
- Wurmser AE and Emr SD (2002) Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy. J Cell Biol 158(4):761-72 PMID:12186856
- Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 PMID:11157979
- Takahashi T, et al. (2001) Identification of genes required for growth under ethanol stress using transposon mutagenesis in Saccharomyces cerevisiae. Mol Genet Genomics 265(6):1112-9 PMID:11523784
- Yoshida S and Anraku Y (2000) Characterization of staurosporine-sensitive mutants of Saccharomyces cerevisiae: vacuolar functions affect staurosporine sensitivity. Mol Gen Genet 263(5):877-88 PMID:10905355
- Hama H, et al. (1999) Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. J Biol Chem 274(48):34294-300 PMID:10567405
- Tall GG, et al. (1999) The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting. Mol Biol Cell 10(6):1873-89 PMID:10359603
- Burd CG and Emr SD (1998) Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Mol Cell 2(1):157-62 PMID:9702203
- Wurmser AE and Emr SD (1998) Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities. EMBO J 17(17):4930-42 PMID:9724630
- Dove SK, et al. (1997) Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390(6656):187-92 PMID:9367158
- Stack JH, et al. (1995) Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol 129(2):321-34 PMID:7721937
- Woscholski R, et al. (1995) Modulation of the substrate specificity of the mammalian phosphatidylinositol 3-kinase by cholesterol sulfate and sulfatide. Biochemistry 34(36):11489-93 PMID:7547877
- Munn AL and Riezman H (1994) Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes. J Cell Biol 127(2):373-86 PMID:7929582
- Stack JH and Emr SD (1994) Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem 269(50):31552-62 PMID:7989323
- Schu PV, et al. (1993) Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260(5104):88-91 PMID:8385367
- Stack JH, et al. (1993) A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J 12(5):2195-204 PMID:8387919
- Raymond CK, et al. (1992) Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol Biol Cell 3(12):1389-402 PMID:1493335
- Herman PK and Emr SD (1990) Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 10(12):6742-54 PMID:2247081
- Auger KR, et al. (1989) Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae. J Biol Chem 264(34):20181-4 PMID:2555343
- Banta LM, et al. (1988) Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J Cell Biol 107(4):1369-83 PMID:3049619
- Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 PMID:3062374
- Rothman JH and Stevens TH (1986) Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47(6):1041-51 PMID:3536126
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
Reset
Click on a gene or a paper to go to its specific page within SGD. Drag any of the gene or paper objects around
within the visualization for easier viewing and click “Reset” to automatically redraw the diagram.
Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Coorey NV, et al. (2025) The anticancer methylthioadenosine phosphorylase transition-state inhibitor induces autophagy in humanized yeast. Dis Model Mech PMID:40375736
- Kunchala P, et al. (2024) Plasticity of the mitotic spindle in response to karyotype variation. Curr Biol 34(15):3416-3428.e4 PMID:39043187
- Mota MN, et al. (2024) Shared and more specific genetic determinants and pathways underlying yeast tolerance to acetic, butyric, and octanoic acids. Microb Cell Fact 23(1):71 PMID:38419072
- Goldstein O, et al. (2023) Novel variants in genes related to vesicle-mediated-transport modify Parkinson's disease risk. Mol Genet Metab 139(2):107608 PMID:37201419
- Lin Y, et al. (2023) Improved protein production in yeast using cell engineering with genes related to a key factor in the unfolded protein response. Metab Eng 77:152-161 PMID:37044356
- Salita T, et al. (2023) Phosphoinositide and redox dysregulation by the anticancer methylthioadenosine phosphorylase transition state inhibitor. Biochim Biophys Acta Mol Cell Biol Lipids 1868(9):159346 PMID:37301365
- Gokbayrak ZD, et al. (2022) Acetate and hypertonic stress stimulate vacuole membrane fission using distinct mechanisms. PLoS One 17(7):e0271199 PMID:35834522
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Feng Z, et al. (2019) Recruitment of Vps34 PI3K and enrichment of PI3P phosphoinositide in the viral replication compartment is crucial for replication of a positive-strand RNA virus. PLoS Pathog 15(1):e1007530 PMID:30625229
- Kang HM, et al. (2018) Genome-wide identification of 99 autophagy-related (Atg) genes in the monogonont rotifer Brachionus spp. and transcriptional modulation in response to cadmium. Aquat Toxicol 201:73-82 PMID:29885584
- Gómez-Sánchez R, et al. (2017) Monitoring the Formation of Autophagosomal Precursor Structures in Yeast Saccharomyces cerevisiae. Methods Enzymol 588:323-365 PMID:28237109
- Miner GE, et al. (2016) The Central Polybasic Region of the Soluble SNARE (Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor) Vam7 Affects Binding to Phosphatidylinositol 3-Phosphate by the PX (Phox Homology) Domain. J Biol Chem 291(34):17651-63 PMID:27365394
- Bean BD, et al. (2015) Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes. Mol Biol Cell 26(6):1119-28 PMID:25609093
- Fayyadkazan M, et al. (2014) Components of Golgi-to-vacuole trafficking are required for nitrogen- and TORC1-responsive regulation of the yeast GATA factors. Microbiologyopen 3(3):271-87 PMID:24644271
- Navale R, et al. (2014) Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum. PLoS One 9(11):e113220 PMID:25426852
- Voigt O, et al. (2014) Autophagic kinases SmVPS34 and SmVPS15 are required for viability in the filamentous ascomycete Sordaria macrospora. Microbiol Res 169(2-3):128-38 PMID:23953726
- Chen J, et al. (2013) mVps34 deletion in podocytes causes glomerulosclerosis by disrupting intracellular vesicle trafficking. J Am Soc Nephrol 24(2):198-207 PMID:23291473
- Chen JK (2013) PIK3C3/VPS34, the class III PtdIns 3-kinase, plays indispensable roles in the podocyte. Autophagy 9(6):923-4 PMID:23518611
- Devereaux K, et al. (2013) Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis. PLoS One 8(10):e76405 PMID:24098492
- Jaber N and Zong WX (2013) Class III PI3K Vps34: essential roles in autophagy, endocytosis, and heart and liver function. Ann N Y Acad Sci 1280:48-51 PMID:23551104
- Jaber N, et al. (2012) Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci U S A 109(6):2003-8 PMID:22308354
- Lefèbvre F, et al. (2012) Secretory pathway-dependent localization of the Saccharomyces cerevisiae Rho GTPase-activating protein Rgd1p at growth sites. Eukaryot Cell 11(5):590-600 PMID:22447923
- Mizuta M, et al. (2012) Screening for yeast mutants defective in recipient ability for transkingdom conjugation with Escherichia coli revealed importance of vacuolar ATPase activity in the horizontal DNA transfer phenomenon. Microbiol Res 167(5):311-6 PMID:22169356
- Barreto L, et al. (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryot Cell 10(9):1241-50 PMID:21724935
- Gresham D, et al. (2011) System-level analysis of genes and functions affecting survival during nutrient starvation in Saccharomyces cerevisiae. Genetics 187(1):299-317 PMID:20944018
- Jung PP, et al. (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12:331 PMID:21711526
- Ouedraogo JP, et al. (2011) Survival strategies of yeast and filamentous fungi against the antifungal protein AFP. J Biol Chem 286(16):13859-68 PMID:21343301
- Garrenton LS, et al. (2010) Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proc Natl Acad Sci U S A 107(26):11805-10 PMID:20547860
- LeBlanc MA and McMaster CR (2010) Lipid binding requirements for oxysterol-binding protein Kes1 inhibition of autophagy and endosome-trans-Golgi trafficking pathways. J Biol Chem 285(44):33875-84 PMID:20729555
- Nardi T, et al. (2010) Adaptation of yeasts Saccharomyces cerevisiae and Brettanomyces bruxellensis to winemaking conditions: a comparative study of stress genes expression. Appl Microbiol Biotechnol 88(4):925-37 PMID:20730535
- Anand VC, et al. (2009) Genome-wide analysis of AP-3-dependent protein transport in yeast. Mol Biol Cell 20(5):1592-604 PMID:19116312
- Couplan E, et al. (2009) Polyunsaturated fatty acids inhibit PI3K activity in a yeast-based model system. Biotechnol J 4(8):1190-7 PMID:19557793
- Godefroy N, et al. (2009) Identification of autophagy genes in Ciona intestinalis: a new experimental model to study autophagy mechanism. Autophagy 5(6):805-15 PMID:19502774
- Rigden DJ, et al. (2009) Autophagy in protists: Examples of secondary loss, lineage-specific innovations, and the conundrum of remodeling a single mitochondrion. Autophagy 5(6):784-94 PMID:19483474
- Tan SX, et al. (2009) Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Biol Cell 20(5):1493-508 PMID:19129474
- Abe F and Minegishi H (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72 PMID:18245339
- Dehring DA, et al. (2008) A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase. J Biol Chem 283(49):34188-96 PMID:18832381
- Jin YH, et al. (2008) Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genet 4(4):e1000053 PMID:18437200
- Mozdy AD, et al. (2008) Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance. Mol Cell Biol 28(12):4152-61 PMID:18411302
- Puria R, et al. (2008) Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 105(20):7194-9 PMID:18443284
- Schluter C, et al. (2008) Global analysis of yeast endosomal transport identifies the vps55/68 sorting complex. Mol Biol Cell 19(4):1282-94 PMID:18216282
- Mandal AK, et al. (2007) Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation. J Cell Biol 176(3):319-28 PMID:17242065
- Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 PMID:17204848
- Yan Y and Backer JM (2007) Regulation of class III (Vps34) PI3Ks. Biochem Soc Trans 35(Pt 2):239-41 PMID:17371248
- Yen WL, et al. (2007) Atg27 is required for autophagy-dependent cycling of Atg9. Mol Biol Cell 18(2):581-93 PMID:17135291
- Zurita-Martinez SA, et al. (2007) Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. Genetics 176(4):2139-50 PMID:17565946
- Freimoser FM, et al. (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109 PMID:17107617
- Gatbonton T, et al. (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35 PMID:16552446
- Hall BS, et al. (2006) TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation. J Biol Chem 281(37):27600-12 PMID:16835237
- Hancock LC, et al. (2006) Genomic analysis of the Opi- phenotype. Genetics 173(2):621-34 PMID:16582425
- Rand JD and Grant CM (2006) The thioredoxin system protects ribosomes against stress-induced aggregation. Mol Biol Cell 17(1):387-401 PMID:16251355
- Reiner S, et al. (2006) A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast. Mol Biol Cell 17(1):90-103 PMID:16251356
- Wagner MC, et al. (2006) Loss of the homotypic fusion and vacuole protein sorting or golgi-associated retrograde protein vesicle tethering complexes results in gentamicin sensitivity in the yeast Saccharomyces cerevisiae. Antimicrob Agents Chemother 50(2):587-95 PMID:16436714
- van Voorst F, et al. (2006) Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress. Yeast 23(5):351-9 PMID:16598687
- Günther J, et al. (2005) Generation and functional in vivo characterization of a lipid kinase defective phosphatidylinositol 3-kinase Vps34p of Candida albicans. Microbiology (Reading) 151(Pt 1):81-89 PMID:15632428
- Rodríguez-Escudero I, et al. (2005) Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. Biochem J 390(Pt 2):613-23 PMID:15913452
- Sambade M, et al. (2005) A genomic screen for yeast vacuolar membrane ATPase mutants. Genetics 170(4):1539-51 PMID:15937126
- Tahirovic S, et al. (2005) Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase. Traffic 6(2):116-30 PMID:15634212
- Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 PMID:15161972
- Serrano R, et al. (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704 PMID:14993228
- Blackburn AS and Avery SV (2003) Genome-wide screening of Saccharomyces cerevisiae to identify genes required for antibiotic insusceptibility of eukaryotes. Antimicrob Agents Chemother 47(2):676-81 PMID:12543677
- Friant S, et al. (2003) Ent3p Is a PtdIns(3,5)P2 effector required for protein sorting to the multivesicular body. Dev Cell 5(3):499-511 PMID:12967568
- Wenk MR, et al. (2003) Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry. Nat Biotechnol 21(7):813-7 PMID:12808461
- Xue Y, et al. (2003) Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans. J Biol Chem 278(36):34380-6 PMID:12788949
- Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 PMID:11907266
- Levine TP and Munro S (2002) Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components. Curr Biol 12(9):695-704 PMID:12007412
- Deloche O, et al. (2001) Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesicles. Mol Biol Cell 12(2):475-85 PMID:11179429
- Aoki H, et al. (2000) Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans. Mol Gen Genet 264(1-2):119-26 PMID:11016841
- Eck R, et al. (2000) A phosphatidylinositol 3-kinase of Candida albicans: molecular cloning and characterization. Yeast 16(10):933-44 PMID:10870104
- Gillooly DJ, et al. (2000) Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J 19(17):4577-88 PMID:10970851
- Kunz J, et al. (2000) HEAT repeats mediate plasma membrane localization of Tor2p in yeast. J Biol Chem 275(47):37011-20 PMID:10973982
- Kiel JA, et al. (1999) The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p. Yeast 15(9):741-54 PMID:10398343
- Peterson MR, et al. (1999) Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome. Curr Biol 9(3):159-62 PMID:10021387
- Gary JD, et al. (1998) Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis. J Cell Biol 143(1):65-79 PMID:9763421
- Odorizzi G, et al. (1998) Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell 95(6):847-58 PMID:9865702
- Panaretou C, et al. (1997) Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex. J Biol Chem 272(4):2477-85 PMID:8999962
- Brown WJ, et al. (1995) Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol 130(4):781-96 PMID:7642697
- Davidson HW (1995) Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J Cell Biol 130(4):797-805 PMID:7642698
- Kimura K, et al. (1995) Phosphatidylinositol-3 kinase in fission yeast: a possible role in stress responses. Biosci Biotechnol Biochem 59(4):678-82 PMID:7772832
- Takegawa K, et al. (1995) Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology. J Cell Sci 108 ( Pt 12):3745-56 PMID:8719881
- Volinia S, et al. (1995) A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J 14(14):3339-48 PMID:7628435
- Zhou K, et al. (1995) A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development. Mol Cell Biol 15(10):5645-56 PMID:7565716
- Kodaki T, et al. (1994) Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. Eur J Biochem 219(3):775-80 PMID:8112328
- Stephens L, et al. (1994) Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells. Curr Biol 4(3):203-14 PMID:7922325
- Welters P, et al. (1994) AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana, is an essential protein with homology to a calcium-dependent lipid binding domain. Proc Natl Acad Sci U S A 91(24):11398-402 PMID:7972072
- Woscholski R, et al. (1994) A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase. FEBS Lett 342(2):109-14 PMID:8143860
- Yoshida S, et al. (1994) A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae. J Biol Chem 269(2):1166-72 PMID:8288577
- Cafferkey R, et al. (1993) Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity. Mol Cell Biol 13(10):6012-23 PMID:8413204
- Flanagan CA, et al. (1993) Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science 262(5138):1444-8 PMID:8248783
- Fry MJ and Waterfield MD (1993) Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control. Philos Trans R Soc Lond B Biol Sci 340(1293):337-44 PMID:8103937
- Hu P, et al. (1993) Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85. Mol Cell Biol 13(12):7677-88 PMID:8246984
- Kunz J, et al. (1993) Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression. Cell 73(3):585-96 PMID:8387896
- Hiles ID, et al. (1992) Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 70(3):419-29 PMID:1322797
- Yoshida S, et al. (1992) Characterization of a staurosporine- and temperature-sensitive mutant, stt1, of Saccharomyces cerevisiae: STT1 is allelic to PKC1. Mol Gen Genet 231(3):337-44 PMID:1538690
- Rothman JH, et al. (1989) Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae. EMBO J 8(7):2057-65 PMID:2676511
Reviews
No reviews curated.
Download References (.nbib)
- Xu L, et al. (2025) Strategic approaches for designing yeast strains as protein secretion and display platforms. Crit Rev Biotechnol 45(3):491-508 PMID:39138023
- Zhang T, et al. (2025) Roles and applications of autophagy in guarding against environmental stress and DNA damage in Saccharomyces cerevisiae. FEBS J PMID:40272088
- Metur SP and Klionsky DJ (2024) Nutrient-dependent signaling pathways that control autophagy in yeast. FEBS Lett 598(1):32-47 PMID:37758520
- Noda NN (2024) Structural view on autophagosome formation. FEBS Lett 598(1):84-106 PMID:37758522
- Capitanio C, et al. (2023) How Membrane Contact Sites Shape the Phagophore. Contact (Thousand Oaks) 6:25152564231162495 PMID:37366413
- Lei Y and Klionsky DJ (2023) Transcriptional regulation of autophagy and its implications in human disease. Cell Death Differ 30(6):1416-1429 PMID:37045910
- Teixeira V (2023) Special Issue: Yeast Cell Signaling Pathways (Volume 1). Int J Mol Sci 24(5) PMID:36902357
- Wang Y, et al. (2023) TORC1 Signaling in Fungi: From Yeasts to Filamentous Fungi. Microorganisms 11(1) PMID:36677510
- Yu P and Hua Z (2023) To Kill or to Be Killed: How Does the Battle between the UPS and Autophagy Maintain the Intracellular Homeostasis in Eukaryotes? Int J Mol Sci 24(3) PMID:36768543
- Caux M, et al. (2022) Class III PI3K Biology. Curr Top Microbiol Immunol 436:69-93 PMID:36243840
- Cámara E, et al. (2022) Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates. Biotechnol Adv 57:107947 PMID:35314324
- Fairman G and Ouimet M (2022) Lipophagy pathways in yeast are controlled by their distinct modes of induction. Yeast 39(8):429-439 PMID:35652813
- Hu Y and Reggiori F (2022) Molecular regulation of autophagosome formation. Biochem Soc Trans 50(1):55-69 PMID:35076688
- Leary KA and Ragusa MJ (2022) Characterization of Protein-Membrane Interactions in Yeast Autophagy. Cells 11(12) PMID:35741004
- Lei Y, et al. (2022) How Cells Deal with the Fluctuating Environment: Autophagy Regulation under Stress in Yeast and Mammalian Systems. Antioxidants (Basel) 11(2) PMID:35204187
- Maitland MER, et al. (2022) Structural and Functional Insights into GID/CTLH E3 Ligase Complexes. Int J Mol Sci 23(11) PMID:35682545
- Majeed ST, et al. (2022) Expanding the view of the molecular mechanisms of autophagy pathway. J Cell Physiol 237(8):3257-3277 PMID:35791448
- Xu DD and Du LL (2022) Fission Yeast Autophagy Machinery. Cells 11(7) PMID:35406650
- Zwilling E and Reggiori F (2022) Membrane Contact Sites in Autophagy. Cells 11(23) PMID:36497073
- Borchers AC, et al. (2021) Who's in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond. J Cell Biol 220(9) PMID:34383013
- Infant T, et al. (2021) Post-translational modifications of proteins associated with yeast peroxisome membrane: An essential mode of regulatory mechanism. Genes Cells 26(11):843-860 PMID:34472666
- Li L, et al. (2021) Lipids and membrane-associated proteins in autophagy. Protein Cell 12(7):520-544 PMID:33151516
- Ohashi Y (2021) Class III phosphatidylinositol 3-kinase complex I subunit NRBF2/Atg38 - from cell and structural biology to health and disease. Autophagy 17(12):3897-3907 PMID:33459128
- Ohashi Y (2021) Activation Mechanisms of the VPS34 Complexes. Cells 10(11) PMID:34831348
- Tavella TA, et al. (2021) Yeast-based high-throughput screens for discovery of kinase inhibitors for neglected diseases. Adv Protein Chem Struct Biol 124:275-309 PMID:33632468
- Kaur S and Changotra H (2020) The beclin 1 interactome: Modification and roles in the pathology of autophagy-related disorders. Biochimie 175:34-49 PMID:32428566
- Patton-Vogt J and de Kroon AIPM (2020) Phospholipid turnover and acyl chain remodeling in the yeast ER. Biochim Biophys Acta Mol Cell Biol Lipids 1865(1):158462 PMID:31146038
- Sieńko K, et al. (2020) Microautophagy in Plants: Consideration of Its Molecular Mechanism. Cells 9(4) PMID:32260410
- Wun CL, et al. (2020) Recent Advances in Membrane Shaping for Plant Autophagosome Biogenesis. Front Plant Sci 11:565 PMID:32547570
- Delorme-Axford E and Klionsky DJ (2019) On the edge of degradation: Autophagy regulation by RNA decay. Wiley Interdiscip Rev RNA 10(3):e1522 PMID:30560575
- Hayek SR, et al. (2019) Reciprocal Regulation of V-ATPase and Glycolytic Pathway Elements in Health and Disease. Front Physiol 10:127 PMID:30828305
- Kirkin V and Rogov VV (2019) A Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy Pathway. Mol Cell 76(2):268-285 PMID:31585693
- Kriegenburg F, et al. (2019) The multi-functional SNARE protein Ykt6 in autophagosomal fusion processes. Cell Cycle 18(6-7):639-651 PMID:30836834
- Lystad AH and Simonsen A (2019) Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery. Cells 8(9) PMID:31450711
- Mamaev DV and Zvyagilskaya RA (2019) Mitophagy in Yeast. Biochemistry (Mosc) 84(Suppl 1):S225-S232 PMID:31213204
- Parzych KR and Klionsky DJ (2019) Vacuolar hydrolysis and efflux: current knowledge and unanswered questions. Autophagy 15(2):212-227 PMID:30422029
- Starr ML and Fratti RA (2019) The Participation of Regulatory Lipids in Vacuole Homotypic Fusion. Trends Biochem Sci 44(6):546-554 PMID:30587414
- Deprez MA, et al. (2018) pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity. Microb Cell 5(3):119-136 PMID:29487859
- Deprez MA, et al. (2018) The TORC1-Sch9 pathway as a crucial mediator of chronological lifespan in the yeast Saccharomyces cerevisiae. FEMS Yeast Res 18(5) PMID:29788208
- Liu ZL (2018) Understanding the tolerance of the industrial yeast Saccharomyces cerevisiae against a major class of toxic aldehyde compounds. Appl Microbiol Biotechnol 102(13):5369-5390 PMID:29725719
- Pierzynowska K, et al. (2018) Autophagy stimulation as a promising approach in treatment of neurodegenerative diseases. Metab Brain Dis 33(4):989-1008 PMID:29542037
- Stroupe C (2018) This Is the End: Regulation of Rab7 Nucleotide Binding in Endolysosomal Trafficking and Autophagy. Front Cell Dev Biol 6:129 PMID:30333976
- Tyler JK and Johnson JE (2018) The role of autophagy in the regulation of yeast life span. Ann N Y Acad Sci 1418(1):31-43 PMID:29363766
- Yoshimoto K and Ohsumi Y (2018) Unveiling the Molecular Mechanisms of Plant Autophagy-From Autophagosomes to Vacuoles in Plants. Plant Cell Physiol 59(7):1337-1344 PMID:29893925
- Anding AL and Baehrecke EH (2017) Cleaning House: Selective Autophagy of Organelles. Dev Cell 41(1):10-22 PMID:28399394
- De Craene JO, et al. (2017) Phosphoinositides, Major Actors in Membrane Trafficking and Lipid Signaling Pathways. Int J Mol Sci 18(3) PMID:28294977
- Dengjel J and Abeliovich H (2017) Roles of mitophagy in cellular physiology and development. Cell Tissue Res 367(1):95-109 PMID:27488107
- Harnett MM, et al. (2017) From Christian de Duve to Yoshinori Ohsumi: More to autophagy than just dining at home. Biomed J 40(1):9-22 PMID:28411887
- Hsu P and Shi Y (2017) Regulation of autophagy by mitochondrial phospholipids in health and diseases. Biochim Biophys Acta Mol Cell Biol Lipids 1862(1):114-129 PMID:27502688
- Jovanovic-Talisman T and Zilman A (2017) Protein Transport by the Nuclear Pore Complex: Simple Biophysics of a Complex Biomachine. Biophys J 113(1):6-14 PMID:28700925
- Lippai M and Szatmári Z (2017) Autophagy-from molecular mechanisms to clinical relevance. Cell Biol Toxicol 33(2):145-168 PMID:27957648
- Noda T (2017) Regulation of Autophagy through TORC1 and mTORC1. Biomolecules 7(3) PMID:28686223
- Reidick C, et al. (2017) The class III phosphatidylinositol 3-kinase Vps34 in Saccharomyces cerevisiae. Biol Chem 398(5-6):677-685 PMID:27935849
- Suzuki H, et al. (2017) Structural biology of the core autophagy machinery. Curr Opin Struct Biol 43:10-17 PMID:27723509
- Hurley JH and Nogales E (2016) Next-generation electron microscopy in autophagy research. Curr Opin Struct Biol 41:211-216 PMID:27614295
- Just WW and Peränen J (2016) Small GTPases in peroxisome dynamics. Biochim Biophys Acta 1863(5):1006-13 PMID:26775587
- Oeljeklaus S, et al. (2016) Regulation of peroxisome dynamics by phosphorylation. Biochim Biophys Acta 1863(5):1027-37 PMID:26775584
- Snoek T, et al. (2016) How do yeast cells become tolerant to high ethanol concentrations? Curr Genet 62(3):475-80 PMID:26758993
- Torres M (2016) Chapter Two - Heterotrimeric G Protein Ubiquitination as a Regulator of G Protein Signaling. Prog Mol Biol Transl Sci 141:57-83 PMID:27378755
- Wen X and Klionsky DJ (2016) An overview of macroautophagy in yeast. J Mol Biol 428(9 Pt A):1681-99 PMID:26908221
- Winters CM and Chiang HL (2016) Yeast as a Model System to Study Trafficking of Small Vesicles Carrying Signal-less Proteins In and Out of the Cell. Curr Protein Pept Sci 17(8):808-820 PMID:26916166
- Abeliovich H (2015) Regulation of autophagy by amino acid availability in S. cerevisiae and mammalian cells. Amino Acids 47(10):2165-75 PMID:24973972
- Feng Y, et al. (2015) How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy. Trends Cell Biol 25(6):354-63 PMID:25759175
- Goode BL, et al. (2015) Actin and endocytosis in budding yeast. Genetics 199(2):315-58 PMID:25657349
- Noda NN and Inagaki F (2015) Mechanisms of Autophagy. Annu Rev Biophys 44:101-22 PMID:25747593
- Xie Y, et al. (2015) Posttranslational modification of autophagy-related proteins in macroautophagy. Autophagy 11(1):28-45 PMID:25484070
- Engelberg D, et al. (2014) Transmembrane signaling in Saccharomyces cerevisiae as a model for signaling in metazoans: state of the art after 25 years. Cell Signal 26(12):2865-78 PMID:25218923
- Jin M and Klionsky DJ (2014) Regulation of autophagy: modulation of the size and number of autophagosomes. FEBS Lett 588(15):2457-63 PMID:24928445
- Krishnamoorthy P, et al. (2014) Regulatory roles of phosphoinositides in membrane trafficking and their potential impact on cell-wall synthesis and re-modelling. Ann Bot 114(6):1049-57 PMID:24769536
- Schiavi A and Ventura N (2014) The interplay between mitochondria and autophagy and its role in the aging process. Exp Gerontol 56:147-53 PMID:24607515
- Schifferdecker AJ, et al. (2014) The wine and beer yeast Dekkera bruxellensis. Yeast 31(9):323-32 PMID:24932634
- Song Y, et al. (2014) The different molecular mechanisms of mitophagy between yeast and mammals. Crit Rev Eukaryot Gene Expr 24(1):29-38 PMID:24579668
- Stein K and Chiang HL (2014) Exocytosis and Endocytosis of Small Vesicles across the Plasma Membrane in Saccharomyces cerevisiae. Membranes (Basel) 4(3):608-29 PMID:25192542
- Cheng Y, et al. (2013) Therapeutic targeting of autophagy in disease: biology and pharmacology. Pharmacol Rev 65(4):1162-97 PMID:23943849
- Klionsky DJ and Codogno P (2013) The mechanism and physiological function of macroautophagy. J Innate Immun 5(5):427-33 PMID:23774579
- Kohlwein SD, et al. (2013) Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat--store 'em up or burn 'em down. Genetics 193(1):1-50 PMID:23275493
- Lu Q, et al. (2013) Aggrephagy: lessons from C. elegans. Biochem J 452(3):381-90 PMID:23725457
- Nazarko VY and Zhong Q (2013) ULK1 targets Beclin-1 in autophagy. Nat Cell Biol 15(7):727-8 PMID:23817237
- Reggiori F and Klionsky DJ (2013) Autophagic processes in yeast: mechanism, machinery and regulation. Genetics 194(2):341-61 PMID:23733851
- Cebollero E, et al. (2012) Understanding phosphatidylinositol-3-phosphate dynamics during autophagosome biogenesis. Autophagy 8(12):1868-70 PMID:22992453
- Das G, et al. (2012) Regulation and function of autophagy during cell survival and cell death. Cold Spring Harb Perspect Biol 4(6) PMID:22661635
- Henry SA, et al. (2012) Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics 190(2):317-49 PMID:22345606
- Mijaljica D, et al. (2012) The intriguing life of autophagosomes. Int J Mol Sci 13(3):3618-3635 PMID:22489171
- Pyo JO, et al. (2012) Molecules and their functions in autophagy. Exp Mol Med 44(2):73-80 PMID:22257882
- Rubinsztein DC, et al. (2012) Mechanisms of autophagosome biogenesis. Curr Biol 22(1):R29-34 PMID:22240478
- Schuh AL and Audhya A (2012) Phosphoinositide signaling during membrane transport in Saccharomyces cerevisiae. Subcell Biochem 59:35-63 PMID:22374087
- Song Q and Kumar A (2012) An Overview of Autophagy and Yeast Pseudohyphal Growth: Integration of Signaling Pathways during Nitrogen Stress. Cells 1(3):263-83 PMID:24710476
- Till A, et al. (2012) Pexophagy: the selective degradation of peroxisomes. Int J Cell Biol 2012:512721 PMID:22536249
- Bartoszewska M and Kiel JA (2011) The role of macroautophagy in development of filamentous fungi. Antioxid Redox Signal 14(11):2271-87 PMID:20712412
- Brennand A, et al. (2011) Autophagy in parasitic protists: unique features and drug targets. Mol Biochem Parasitol 177(2):83-99 PMID:21315770
- Brill JA, et al. (2011) Phosphoinositide function in cytokinesis. Curr Biol 21(22):R930-4 PMID:22115464
- Kim J and Guan KL (2011) Amino acid signaling in TOR activation. Annu Rev Biochem 80:1001-32 PMID:21548787
- Mizushima N, et al. (2011) The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol 27:107-32 PMID:21801009
- Obara K and Ohsumi Y (2011) Atg14: a key player in orchestrating autophagy. Int J Cell Biol 2011:713435 PMID:22013444
- Obara K and Ohsumi Y (2011) PtdIns 3-Kinase Orchestrates Autophagosome Formation in Yeast. J Lipids 2011:498768 PMID:21490802
- Sibirny AA (2011) Mechanisms of autophagy and pexophagy in yeasts. Biochemistry (Mosc) 76(12):1279-90 PMID:22150273
- Weidberg H, et al. (2011) Biogenesis and cargo selectivity of autophagosomes. Annu Rev Biochem 80:125-56 PMID:21548784
- Bankaitis VA, et al. (2010) The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling. Trends Biochem Sci 35(3):150-60 PMID:19926291
- Coonrod EM and Stevens TH (2010) The yeast vps class E mutants: the beginning of the molecular genetic analysis of multivesicular body biogenesis. Mol Biol Cell 21(23):4057-60 PMID:21115849
- Lynch-Day MA and Klionsky DJ (2010) The Cvt pathway as a model for selective autophagy. FEBS Lett 584(7):1359-66 PMID:20146925
- Manjithaya R, et al. (2010) Molecular mechanism and physiological role of pexophagy. FEBS Lett 584(7):1367-73 PMID:20083110
- Mizushima N (2010) Autophagy. FEBS Lett 584(7):1279 PMID:20184884
- Stanley D, et al. (2010) The ethanol stress response and ethanol tolerance of Saccharomyces cerevisiae. J Appl Microbiol 109(1):13-24 PMID:20070446
- Suzuki K and Ohsumi Y (2010) Current knowledge of the pre-autophagosomal structure (PAS). FEBS Lett 584(7):1280-6 PMID:20138172
- Tooze SA and Yoshimori T (2010) The origin of the autophagosomal membrane. Nat Cell Biol 12(9):831-5 PMID:20811355
- Yuan TL and Cantley LC (2010) Introduction. Curr Top Microbiol Immunol 346:1-7 PMID:20582535
- Ding J, et al. (2009) Tolerance and stress response to ethanol in the yeast Saccharomyces cerevisiae. Appl Microbiol Biotechnol 85(2):253-63 PMID:19756577
- Dove SK, et al. (2009) Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function. Biochem J 419(1):1-13 PMID:19272020
- Dwivedi M and Ahnn J (2009) Autophagy--is it a preferred route for lifespan extension? BMB Rep 42(2):62-71 PMID:19250605
- Farré JC, et al. (2009) Turnover of organelles by autophagy in yeast. Curr Opin Cell Biol 21(4):522-30 PMID:19515549
- Kourtis N and Tavernarakis N (2009) Autophagy and cell death in model organisms. Cell Death Differ 16(1):21-30 PMID:19079286
- Li SC and Kane PM (2009) The yeast lysosome-like vacuole: endpoint and crossroads. Biochim Biophys Acta 1793(4):650-63 PMID:18786576
- Mayinger P (2009) Regulation of Golgi function via phosphoinositide lipids. Semin Cell Dev Biol 20(7):793-800 PMID:19508852
- Nakatogawa H, et al. (2009) Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol 10(7):458-67 PMID:19491929
- Pollack JK, et al. (2009) Autophagy in filamentous fungi. Fungal Genet Biol 46(1):1-8 PMID:19010432
- Stipanuk MH (2009) Macroautophagy and its role in nutrient homeostasis. Nutr Rev 67(12):677-89 PMID:19941614
- Vellai T (2009) Autophagy genes and ageing. Cell Death Differ 16(1):94-102 PMID:19079287
- Backer JM (2008) The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem J 410(1):1-17 PMID:18215151
- Dechant R and Peter M (2008) Nutrient signals driving cell growth. Curr Opin Cell Biol 20(6):678-87 PMID:18930818
- Deretic V (2008) Autophagosome and phagosome. Methods Mol Biol 445:1-10 PMID:18425440
- Jacinto E (2008) What controls TOR? IUBMB Life 60(8):483-96 PMID:18493947
- Yoshimori T and Noda T (2008) Toward unraveling membrane biogenesis in mammalian autophagy. Curr Opin Cell Biol 20(4):401-7 PMID:18472412
- Hao N, et al. (2007) Systems biology analysis of G protein and MAP kinase signaling in yeast. Oncogene 26(22):3254-66 PMID:17496920
- Souza CM and Pichler H (2007) Lipid requirements for endocytosis in yeast. Biochim Biophys Acta 1771(3):442-54 PMID:16997624
- Strahl T and Thorner J (2007) Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta 1771(3):353-404 PMID:17382260
- Suzuki K and Ohsumi Y (2007) Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett 581(11):2156-61 PMID:17382324
- Xie Z and Klionsky DJ (2007) Autophagosome formation: core machinery and adaptations. Nat Cell Biol 9(10):1102-9 PMID:17909521
- Bardwell L (2006) G-protein signaling: a new branch in an old pathway. Curr Biol 16(19):R853-5 PMID:17027484
- Dohlman HG and Slessareva JE (2006) Pheromone signaling pathways in yeast. Sci STKE 2006(364):cm6 PMID:17148787
- Reggiori F (2006) 1. Membrane origin for autophagy. Curr Top Dev Biol 74:1-30 PMID:16860663
- Slessareva JE and Dohlman HG (2006) G protein signaling in yeast: new components, new connections, new compartments. Science 314(5804):1412-3 PMID:17138892
- Klionsky DJ (2005) The molecular machinery of autophagy: unanswered questions. J Cell Sci 118(Pt 1):7-18 PMID:15615779
- Pendaries C, et al. (2005) Emerging roles of phosphatidylinositol monophosphates in cellular signaling and trafficking. Adv Enzyme Regul 45:201-14 PMID:16023705
- Seaman MN (2005) Recycle your receptors with retromer. Trends Cell Biol 15(2):68-75 PMID:15695093
- Yang YP, et al. (2005) Molecular mechanism and regulation of autophagy. Acta Pharmacol Sin 26(12):1421-34 PMID:16297339
- Yorimitsu T and Klionsky DJ (2005) Autophagy: molecular machinery for self-eating. Cell Death Differ 12 Suppl 2(Suppl 2):1542-52 PMID:16247502
- Farré JC and Subramani S (2004) Peroxisome turnover by micropexophagy: an autophagy-related process. Trends Cell Biol 14(9):515-23 PMID:15350980
- Gruenberg J and Stenmark H (2004) The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol 5(4):317-23 PMID:15071556
- Luzio JP, et al. (2003) Membrane dynamics and the biogenesis of lysosomes. Mol Membr Biol 20(2):141-54 PMID:12851071
- Weisman LS (2003) Yeast vacuole inheritance and dynamics. Annu Rev Genet 37:435-60 PMID:14616069
- De Matteis M, et al. (2002) Phosphoinositides and the golgi complex. Curr Opin Cell Biol 14(4):434-47 PMID:12383794
- Stenmark H, et al. (2002) The phosphatidylinositol 3-phosphate-binding FYVE finger. FEBS Lett 513(1):77-84 PMID:11911884
- Abeliovich H and Klionsky DJ (2001) Autophagy in yeast: mechanistic insights and physiological function. Microbiol Mol Biol Rev 65(3):463-79, table of contents PMID:11528006
- Gillooly DJ, et al. (2001) Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem J 355(Pt 2):249-58 PMID:11284710
- Kucharczyk R and Rytka J (2001) Saccharomyces cerevisiae--a model organism for the studies on vacuolar transport. Acta Biochim Pol 48(4):1025-42 PMID:11995965
- McMaster CR (2001) Lipid metabolism and vesicle trafficking: more than just greasing the transport machinery. Biochem Cell Biol 79(6):681-92 PMID:11800009
- Wera S, et al. (2001) Phosphoinositides in yeast: genetically tractable signalling. FEMS Yeast Res 1(1):9-13 PMID:12702458
- D'Hondt K, et al. (2000) Protein and lipid requirements for endocytosis. Annu Rev Genet 34:255-295 PMID:11092829
- Huijbregts RP, et al. (2000) Lipid metabolism and regulation of membrane trafficking. Traffic 1(3):195-202 PMID:11208102
- Lemmon SK and Traub LM (2000) Sorting in the endosomal system in yeast and animal cells. Curr Opin Cell Biol 12(4):457-66 PMID:10873832
- Munn AL (2000) The yeast endocytic membrane transport system. Microsc Res Tech 51(6):547-62 PMID:11169857
- Odorizzi G, et al. (2000) Phosphoinositide signaling and the regulation of membrane trafficking in yeast. Trends Biochem Sci 25(5):229-35 PMID:10782093
- Anderson RA, et al. (1999) Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes. J Biol Chem 274(15):9907-10 PMID:10187762
- Götte M and Lazar T (1999) The ins and outs of yeast vacuole trafficking. Protoplasma 209(1-2):9-18 PMID:18987790
- Vessey CJ, et al. (1999) Genetic disorders associated with cancer predisposition and genomic instability. Prog Nucleic Acid Res Mol Biol 63:189-221 PMID:10506832
- Wurmser AE, et al. (1999) Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways. J Biol Chem 274(14):9129-32 PMID:10092582
- Bryant NJ and Stevens TH (1998) Vacuole biogenesis in Saccharomyces cerevisiae: protein transport pathways to the yeast vacuole. Microbiol Mol Biol Rev 62(1):230-47 PMID:9529893
- Conibear E and Stevens TH (1998) Multiple sorting pathways between the late Golgi and the vacuole in yeast. Biochim Biophys Acta 1404(1-2):211-30 PMID:9714809
- Daum G, et al. (1998) Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast 14(16):1471-510 PMID:9885152
- Fruman DA, et al. (1998) Phosphoinositide kinases. Annu Rev Biochem 67:481-507 PMID:9759495
- Wymann MP and Pirola L (1998) Structure and function of phosphoinositide 3-kinases. Biochim Biophys Acta 1436(1-2):127-50 PMID:9838078
- DeWald DB, et al. (1997) Regulation of the Saccharomyces cerevisiae Vps34p phosphatidylinositol 3-kinase. Biochem Soc Trans 25(4):1141-6 PMID:9449964
- Hunter T and Plowman GD (1997) The protein kinases of budding yeast: six score and more. Trends Biochem Sci 22(1):18-22 PMID:9020587
- De Camilli P, et al. (1996) Phosphoinositides as regulators in membrane traffic. Science 271(5255):1533-9 PMID:8599109
- Conibear E and Stevens TH (1995) Vacuolar biogenesis in yeast: sorting out the sorting proteins. Cell 83(4):513-6 PMID:7585951
- Horazdovsky BF, et al. (1995) Protein transport to the yeast vacuole. Curr Opin Cell Biol 7(4):544-51 PMID:7495575
- Stack JH, et al. (1995) Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteins. Annu Rev Cell Dev Biol 11:1-33 PMID:8689553
- Pryer NK, et al. (1992) Vesicle-mediated protein sorting. Annu Rev Biochem 61:471-516 PMID:1497318
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Rangarajan N, et al. (2020) Potassium starvation induces autophagy in yeast. J Biol Chem 295(41):14189-14202 PMID:32788210
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Gaur NA, et al. (2013) Vps factors are required for efficient transcription elongation in budding yeast. Genetics 193(3):829-51 PMID:23335340
- Grunau S, et al. (2011) The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae. Biochem J 434(1):161-70 PMID:21121900
- Wiederhold E, et al. (2009) The yeast vacuolar membrane proteome. Mol Cell Proteomics 8(2):380-92 PMID:19001347
- Obara K, et al. (2006) Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell 17(4):1527-39 PMID:16421251
- Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 PMID:11157979
- Stack JH and Emr SD (1994) Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities. J Biol Chem 269(50):31552-62 PMID:7989323
- Schu PV, et al. (1993) Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260(5104):88-91 PMID:8385367
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Suda K, et al. (2024) Plasma membrane damage limits replicative lifespan in yeast and induces premature senescence in human fibroblasts. Nat Aging 4(3):319-335 PMID:38388781
- Laidlaw KME, et al. (2022) Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation. Mol Biol Cell 33(4):ar31 PMID:35080991
- Jin X, et al. (2021) Retromer Complex and PI3K Complex II-Related Genes Mediate the Yeast (Saccharomyces cerevisiae) Sodium Metabisulfite Resistance Response. Cells 10(12) PMID:34944020
- Steinfeld N, et al. (2021) Elevating PI3P drives select downstream membrane trafficking pathways. Mol Biol Cell 32(2):143-156 PMID:33237833
- Chen S, et al. (2020) Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy. Proc Natl Acad Sci U S A 117(31):18530-18539 PMID:32690699
- Rangarajan N, et al. (2020) Potassium starvation induces autophagy in yeast. J Biol Chem 295(41):14189-14202 PMID:32788210
- Uemura S, et al. (2020) Amino acid homeostatic control by TORC1 in Saccharomyces cerevisiae under high hydrostatic pressure. J Cell Sci 133(17) PMID:32801125
- Ukai H, et al. (2018) Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane. PLoS Genet 14(4):e1007334 PMID:29698392
- Kim A and Cunningham KW (2015) A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress. Mol Biol Cell 26(25):4631-45 PMID:26510498
- Cruz-Garcia D, et al. (2014) Remodeling of secretory compartments creates CUPS during nutrient starvation. J Cell Biol 207(6):695-703 PMID:25512390
- Gaur NA, et al. (2013) Vps factors are required for efficient transcription elongation in budding yeast. Genetics 193(3):829-51 PMID:23335340
- Alex D, et al. (2012) Amino acid-derived 1,2-benzisothiazolinone derivatives as novel small-molecule antifungal inhibitors: identification of potential genetic targets. Antimicrob Agents Chemother 56(9):4630-9 PMID:22687516
- Galluzzi L, et al. (2012) Independent transcriptional reprogramming and apoptosis induction by cisplatin. Cell Cycle 11(18):3472-80 PMID:22918244
- Mániková D, et al. (2012) Selenium toxicity toward yeast as assessed by microarray analysis and deletion mutant library screen: a role for DNA repair. Chem Res Toxicol 25(8):1598-608 PMID:22747191
- Zieger M and Mayer A (2012) Yeast vacuoles fragment in an asymmetrical two-phase process with distinct protein requirements. Mol Biol Cell 23(17):3438-49 PMID:22787281
- Bruns C, et al. (2011) Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion. J Cell Biol 195(6):979-92 PMID:22144692
- Banuelos MG, et al. (2010) Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae. Curr Genet 56(2):121-37 PMID:20043226
- Huber A, et al. (2009) Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev 23(16):1929-43 PMID:19684113
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Obara K, et al. (2008) Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae. Genes Cells 13(6):537-47 PMID:18533003
- Zhang F, et al. (2008) Disrupting vesicular trafficking at the endosome attenuates transcriptional activation by Gcn4. Mol Cell Biol 28(22):6796-818 PMID:18794364
- Pagani MA, et al. (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol Microbiol 65(2):521-37 PMID:17630978
- Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 PMID:16839886
- Reggiori F, et al. (2004) Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Mol Biol Cell 15(5):2189-204 PMID:15004240
- Strømhaug PE, et al. (2004) Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Mol Biol Cell 15(8):3553-66 PMID:15155809
- Katzmann DJ, et al. (2003) Vps27 recruits ESCRT machinery to endosomes during MVB sorting. J Cell Biol 162(3):413-23 PMID:12900393
- Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 PMID:11157979
- Takahashi T, et al. (2001) Identification of genes required for growth under ethanol stress using transposon mutagenesis in Saccharomyces cerevisiae. Mol Genet Genomics 265(6):1112-9 PMID:11523784
- Yoshida S and Anraku Y (2000) Characterization of staurosporine-sensitive mutants of Saccharomyces cerevisiae: vacuolar functions affect staurosporine sensitivity. Mol Gen Genet 263(5):877-88 PMID:10905355
- Wurmser AE and Emr SD (1998) Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities. EMBO J 17(17):4930-42 PMID:9724630
- Stack JH, et al. (1995) Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast. J Cell Biol 129(2):321-34 PMID:7721937
- Munn AL and Riezman H (1994) Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes. J Cell Biol 127(2):373-86 PMID:7929582
- Schu PV, et al. (1993) Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science 260(5104):88-91 PMID:8385367
- Raymond CK, et al. (1992) Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol Biol Cell 3(12):1389-402 PMID:1493335
- Herman PK and Emr SD (1990) Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol 10(12):6742-54 PMID:2247081
- Banta LM, et al. (1988) Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. J Cell Biol 107(4):1369-83 PMID:3049619
- Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 PMID:3062374
- Rothman JH and Stevens TH (1986) Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47(6):1041-51 PMID:3536126
Disease Literature
Paper(s) associated with one or more pieces of disease evidence in SGD, as found on the Disease page.
No disease literature curated.
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Filali-Mouncef Y, et al. (2024) An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae. Autophagy 20(10):2323-2337 PMID:38958087
- Mirisola MG and Longo VD (2024) Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast. Biomed J 47(2):100694 PMID:38154617
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Carey SB, et al. (2023) A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. G3 (Bethesda) 13(1) PMID:36409020
- Cohen N, et al. (2023) A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon. EMBO J 42(11):e113385 PMID:37073826
- Hitomi K, et al. (2023) The Atg1 complex, Atg9, and Vac8 recruit PI3K complex I to the pre-autophagosomal structure. J Cell Biol 222(8) PMID:37436710
- Kolhe JA, et al. (2023) The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions. Mol Cell 83(12):2035-2044.e7 PMID:37295430
- Lee Y, et al. (2023) Atg1-dependent phosphorylation of Vps34 is required for dynamic regulation of the phagophore assembly site and autophagy in Saccharomyces cerevisiae. Autophagy 19(9):2428-2442 PMID:36803233
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Jaworek W, et al. (2022) Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress. J Biol Chem 298(10):102494 PMID:36115461
- Shortill SP, et al. (2022) The VINE complex is an endosomal VPS9-domain GEF and SNX-BAR coat. Elife 11 PMID:35938928
- Yang X, et al. (2022) The ubiquitin-proteasome system regulates meiotic chromosome organization. Proc Natl Acad Sci U S A 119(17):e2106902119 PMID:35439061
- Zhao L, et al. (2022) Vps21 Directs the PI3K-PI(3)P-Atg21-Atg16 Module to Phagophores via Vps8 for Autophagy. Int J Mol Sci 23(17) PMID:36076954
- Hollenstein DM, et al. (2021) Spatial control of avidity regulates initiation and progression of selective autophagy. Nat Commun 12(1):7194 PMID:34893607
- Leng H, et al. (2021) FACT interacts with Set3 HDAC and fine-tunes GAL1 transcription in response to environmental stimulation. Nucleic Acids Res 49(10):5502-5519 PMID:33963860
- Schreiber A, et al. (2021) Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation. Mol Cell 81(24):5066-5081.e10 PMID:34798055
- Steinfeld N, et al. (2021) Elevating PI3P drives select downstream membrane trafficking pathways. Mol Biol Cell 32(2):143-156 PMID:33237833
- Yao W, et al. (2020) Atg11 is required for initiation of glucose starvation-induced autophagy. Autophagy 16(12):2206-2218 PMID:31971848
- Böckler S, et al. (2017) Fusion, fission, and transport control asymmetric inheritance of mitochondria and protein aggregates. J Cell Biol 216(8):2481-2498 PMID:28615194
- Babour A, et al. (2016) The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell 167(5):1201-1214.e15 PMID:27863241
- Ohashi Y, et al. (2016) Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. Autophagy 12(11):2129-2144 PMID:27630019
- Imamura Y, et al. (2015) RSC Chromatin-Remodeling Complex Is Important for Mitochondrial Function in Saccharomyces cerevisiae. PLoS One 10(6):e0130397 PMID:26086550
- Voynova NS, et al. (2015) Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated. Eukaryot Cell 14(12):1203-16 PMID:26432633
- Araki Y, et al. (2013) Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity. J Cell Biol 203(2):299-313 PMID:24165940
- Graef M, et al. (2013) ER exit sites are physical and functional core autophagosome biogenesis components. Mol Biol Cell 24(18):2918-31 PMID:23904270
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Grunau S, et al. (2011) The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae. Biochem J 434(1):161-70 PMID:21121900
- Breitkreutz A, et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6 PMID:20489023
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Lin YY, et al. (2008) A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev 22(15):2062-74 PMID:18676811
- Zurita-Martinez SA, et al. (2007) Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. Genetics 176(4):2139-50 PMID:17565946
- Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440(7084):631-6 PMID:16429126
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Obara K, et al. (2006) Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell 17(4):1527-39 PMID:16421251
- Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 PMID:16487579
- Slessareva JE, et al. (2006) Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome. Cell 126(1):191-203 PMID:16839886
- Tahirovic S, et al. (2005) Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase. Traffic 6(2):116-30 PMID:15634212
- Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1:2005.0026 PMID:16729061
- Budovskaya YV, et al. (2002) The C terminus of the Vps34p phosphoinositide 3-kinase is necessary and sufficient for the interaction with the Vps15p protein kinase. J Biol Chem 277(1):287-94 PMID:11689570
- Gurunathan S, et al. (2002) Dynamin and clathrin are required for the biogenesis of a distinct class of secretory vesicles in yeast. EMBO J 21(4):602-14 PMID:11847108
- Kihara A, et al. (2001) Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 152(3):519-30 PMID:11157979
- Conibear E and Stevens TH (2000) Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi. Mol Biol Cell 11(1):305-23 PMID:10637310
- Tall GG, et al. (1999) The phosphatidylinositol 3-phosphate binding protein Vac1p interacts with a Rab GTPase and a Sec1p homologue to facilitate vesicle-mediated vacuolar protein sorting. Mol Biol Cell 10(6):1873-89 PMID:10359603
- Munn AL and Riezman H (1994) Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes. J Cell Biol 127(2):373-86 PMID:7929582
- Stack JH, et al. (1993) A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO J 12(5):2195-204 PMID:8387919
- Herman PK, et al. (1992) An essential role for a protein and lipid kinase complex in secretory protein sorting. Trends Cell Biol 2(12):363-8 PMID:14731957
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Download References (.nbib)
- Lee Y, et al. (2023) Atg1-dependent phosphorylation of Vps34 is required for dynamic regulation of the phagophore assembly site and autophagy in Saccharomyces cerevisiae. Autophagy 19(9):2428-2442 PMID:36803233
- Uppala JK, et al. (2021) Vps34 and TOR Kinases Coordinate HAC1 mRNA Translation in the Presence or Absence of Ire1-Dependent Splicing. Mol Cell Biol 41(7):e0066220 PMID:33972394
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Leutert M, et al. (2023) The regulatory landscape of the yeast phosphoproteome. Nat Struct Mol Biol 30(11):1761-1773 PMID:37845410
- Dokládal L, et al. (2021) Phosphoproteomic responses of TORC1 target kinases reveal discrete and convergent mechanisms that orchestrate the quiescence program in yeast. Cell Rep 37(13):110149 PMID:34965436
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Swaney DL, et al. (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10(7):676-82 PMID:23749301
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Fierling N, et al. (2024) Global deletome profile of Saccharomyces cerevisiae exposed to lithium. Metallomics 16(1) PMID:38142127
- Kunchala P, et al. (2024) Plasticity of the mitotic spindle in response to karyotype variation. Curr Biol 34(15):3416-3428.e4 PMID:39043187
- Mota MN, et al. (2024) Shared and more specific genetic determinants and pathways underlying yeast tolerance to acetic, butyric, and octanoic acids. Microb Cell Fact 23(1):71 PMID:38419072
- Grosjean N, et al. (2023) Yeast Deletomics to Uncover Gadolinium Toxicity Targets and Resistance Mechanisms. Microorganisms 11(8) PMID:37630673
- Coey CT and Clark DJ (2022) A systematic genome-wide account of binding sites for the model transcription factor Gcn4. Genome Res 32(2):367-377 PMID:34916251
- Goh CJH, et al. (2022) Diethyl phthalate (DEP) perturbs nitrogen metabolism in Saccharomyces cerevisiae. Sci Rep 12(1):10237 PMID:35715465
- Dokládal L, et al. (2021) Phosphoproteomic responses of TORC1 target kinases reveal discrete and convergent mechanisms that orchestrate the quiescence program in yeast. Cell Rep 37(13):110149 PMID:34965436
- Nicastro R, et al. (2021) Indole-3-acetic acid is a physiological inhibitor of TORC1 in yeast. PLoS Genet 17(3):e1009414 PMID:33690632
- Chen S, et al. (2020) Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy. Proc Natl Acad Sci U S A 117(31):18530-18539 PMID:32690699
- Johnston NR, et al. (2020) Genome-Wide Identification of Genes Involved in General Acid Stress and Fluoride Toxicity in Saccharomyces cerevisiae. Front Microbiol 11:1410 PMID:32670247
- Molin M, et al. (2020) Protein kinase A controls yeast growth in visible light. BMC Biol 18(1):168 PMID:33198745
- Stenger M, et al. (2020) Systematic analysis of nuclear gene function in respiratory growth and expression of the mitochondrial genome in S. cerevisiae. Microb Cell 7(9):234-249 PMID:32904421
- Chakrabortee S, et al. (2016) Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits. Cell 167(2):369-381.e12 PMID:27693355
- Bin-Umer MA, et al. (2014) Elimination of damaged mitochondria through mitophagy reduces mitochondrial oxidative stress and increases tolerance to trichothecenes. Proc Natl Acad Sci U S A 111(32):11798-803 PMID:25071194
- Gaupel AC, et al. (2014) High throughput screening identifies modulators of histone deacetylase inhibitors. BMC Genomics 15(1):528 PMID:24968945
- Pereira FB, et al. (2014) Genome-wide screening of Saccharomyces cerevisiae genes required to foster tolerance towards industrial wheat straw hydrolysates. J Ind Microbiol Biotechnol 41(12):1753-61 PMID:25287021
- González-Ramos D, et al. (2013) Genome-scale analyses of butanol tolerance in Saccharomyces cerevisiae reveal an essential role of protein degradation. Biotechnol Biofuels 6(1):48 PMID:23552365
- Marek A and Korona R (2013) Restricted pleiotropy facilitates mutational erosion of major life-history traits. Evolution 67(11):3077-86 PMID:24151994
- Davey HM, et al. (2012) Genome-wide analysis of longevity in nutrient-deprived Saccharomyces cerevisiae reveals importance of recycling in maintaining cell viability. Environ Microbiol 14(5):1249-60 PMID:22356628
- Huang Z, et al. (2012) Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategy. PLoS Genet 8(11):e1003083 PMID:23209439
- Kim H, et al. (2012) Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeast. J Biol Chem 287(23):19029-39 PMID:22511765
- Orij R, et al. (2012) Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae. Genome Biol 13(9):R80 PMID:23021432
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Schmidt M, et al. (2012) Role of Hog1, Tps1 and Sod1 in boric acid tolerance of Saccharomyces cerevisiae. Microbiology (Reading) 158(Pt 10):2667-2678 PMID:22902726
- Yu D, et al. (2012) High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome. BMC Genomics 13:623 PMID:23151179
- Barreto L, et al. (2011) A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae. Eukaryot Cell 10(9):1241-50 PMID:21724935
- Bleackley MR, et al. (2011) High density array screening to identify the genetic requirements for transition metal tolerance in Saccharomyces cerevisiae. Metallomics 3(2):195-205 PMID:21212869
- Burtner CR, et al. (2011) A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle 10(9):1385-96 PMID:21447998
- Hoon S, et al. (2011) A global perspective of the genetic basis for carbonyl stress resistance. G3 (Bethesda) 1(3):219-31 PMID:22384333
- Teng X, et al. (2011) Gene-dependent cell death in yeast. Cell Death Dis 2(8):e188 PMID:21814286
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61 PMID:21341307
- Banuelos MG, et al. (2010) Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae. Curr Genet 56(2):121-37 PMID:20043226
- Batova M, et al. (2010) Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine). BMC Genomics 11:153 PMID:20202201
- Dakshinamurthy A, et al. (2010) BUD22 affects Ty1 retrotransposition and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 185(4):1193-205 PMID:20498295
- Dowell RD, et al. (2010) Genotype to phenotype: a complex problem. Science 328(5977):469 PMID:20413493
- Anand VC, et al. (2009) Genome-wide analysis of AP-3-dependent protein transport in yeast. Mol Biol Cell 20(5):1592-604 PMID:19116312
- Auesukaree C, et al. (2009) Genome-wide identification of genes involved in tolerance to various environmental stresses in Saccharomyces cerevisiae. J Appl Genet 50(3):301-10 PMID:19638689
- Holbein S, et al. (2009) Cordycepin interferes with 3' end formation in yeast independently of its potential to terminate RNA chain elongation. RNA 15(5):837-49 PMID:19324962
- Tan SX, et al. (2009) Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Biol Cell 20(5):1493-508 PMID:19129474
- Westmoreland TJ, et al. (2009) Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. PLoS One 4(6):e5830 PMID:19503795
- Abe F and Minegishi H (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72 PMID:18245339
- Gustavsson M, et al. (2008) Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics 280(3):233-48 PMID:18612650
- Jin YH, et al. (2008) Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genet 4(4):e1000053 PMID:18437200
- Mozdy AD, et al. (2008) Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance. Mol Cell Biol 28(12):4152-61 PMID:18411302
- Sinha H, et al. (2008) Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. Genetics 180(3):1661-70 PMID:18780730
- Botet J, et al. (2007) A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase. Eukaryot Cell 6(11):2102-11 PMID:17873082
- Cai H, et al. (2006) Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae. Genetics 172(3):1459-76 PMID:16361226
- Freimoser FM, et al. (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109 PMID:17107617
- Gatbonton T, et al. (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35 PMID:16552446
- Hancock LC, et al. (2006) Genomic analysis of the Opi- phenotype. Genetics 173(2):621-34 PMID:16582425
- Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36 PMID:16911514
- Rand JD and Grant CM (2006) The thioredoxin system protects ribosomes against stress-induced aggregation. Mol Biol Cell 17(1):387-401 PMID:16251355
- Reiner S, et al. (2006) A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast. Mol Biol Cell 17(1):90-103 PMID:16251356
- van Voorst F, et al. (2006) Genome-wide identification of genes required for growth of Saccharomyces cerevisiae under ethanol stress. Yeast 23(5):351-9 PMID:16598687
- Deutschbauer AM, et al. (2005) Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics 169(4):1915-25 PMID:15716499
- Proszynski TJ, et al. (2005) A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. Proc Natl Acad Sci U S A 102(50):17981-6 PMID:16330752
- Sambade M, et al. (2005) A genomic screen for yeast vacuolar membrane ATPase mutants. Genetics 170(4):1539-51 PMID:15937126
- Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 PMID:15161972
- Hartman JL and Tippery NP (2004) Systematic quantification of gene interactions by phenotypic array analysis. Genome Biol 5(7):R49 PMID:15239834
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Mollapour M, et al. (2004) Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast 21(11):927-46 PMID:15334557
- Serrano R, et al. (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704 PMID:14993228
- Blackburn AS and Avery SV (2003) Genome-wide screening of Saccharomyces cerevisiae to identify genes required for antibiotic insusceptibility of eukaryotes. Antimicrob Agents Chemother 47(2):676-81 PMID:12543677
- Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 PMID:11907266
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400 PMID:12089449
- Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42 PMID:12096123
- Ni L and Snyder M (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70 PMID:11452010