Phenotype Help

COQ9 / YLR201C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene in reference strain S288C; null mutant fails to respire and exhibits sensitivity to linoleic acid; in large-scale studies, the null mutant shows reduced competitive fitness and chronological lifespan, sensitivity to desiccation, starvation, and oxidative stress, and altered resistance to various chemicals; overexpression causes reduced filamentous growth

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

50 entries for 19 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
chemical compound accumulation: decreased
homozygous diploid, systematic mutation set

glycogen accumulation in diploid mutant strains grown in microtiter plates

null
Allele: coq9-Δ
S288C glycogenWilson WA, et al. (2002) PMID:12096123
chemical compound accumulation: increased
systematic mutation setnull
Allele: coq9-Δ
S288C hydrogen sulfideMedia: cysteine supplementation, 500 mg/L
Winter G, et al. (2014) PMID:25517415
chronological lifespan: decreased
systematic mutation setnull
Allele: coq9-Δ
S288CMarek A and Korona R (2013) PMID:24151994
chronological lifespan: decreased
large-scale survey null
Allele: coq9-Δ
S288CDetails: one of the top 30 short-lived strains lacking a single nuclear-encoded mitochondrial gene; CLS of 22 days compared to 41 days for wt, a reduction of -45% percent relative to wt
Phua CZJ, et al. (2023) PMID:37086368
competitive fitness: decreased
homozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: coq9-Δ
S288CMedia: YPD
Details: Relative fitness score: 0.925
Deutschbauer AM, et al. (2005) PMID:15716499
competitive fitness: decreased
systematic mutation setnull
Allele: coq9-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: coq9-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: coq9-Δ
S288CMedia: rich medium (YPD) w/6% ethanol, ETH
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: coq9-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: coq9-Δ
S288CMedia: YPD
Qian W, et al. (2012) PMID:23103169
Showing 1 to 10 of 50 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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