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RAD5 / YLR032W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

REV2 11 , SNM2 12
Protein Product
DNA helicase RAD5
Feature Type
ORF , Verified
DNA helicase/Ubiquitin ligase; involved in error-free DNA damage tolerance (DDT), replication fork regression during postreplication repair by template switching, and error-prone translesion synthesis; required for UV and MMS-associated unequal sister chromatid exchange (SCE) but not for double-strand break associated unequal SCE; promotes synthesis of free and PCNA-bound polyubiquitin chains by Ubc13p-Mms2p; human homolog HLTF can complement yeast null mutant 2 3 4 5 6 7 8 9 10