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TPO1 / YLL028W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Feature Type
ORF , Verified
Polyamine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; during oxidative stress exports spermine, spermidine from the cell, which controls timing of expression of stress-responsive genes; phosphorylation enhances activity and sorting to the plasma membrane 1 2 3 4 5