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JHD2 / YJR119C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

KDM5 8 9
Protein Product
histone demethylase
Feature Type
ORF , Verified
JmjC domain family histone demethylase; promotes global demethylation of H3K4 and repression of noncoding intergenic transcription during sporulation; removes methyl groups added by Set1p; negatively regulated by H3K14 acetylation; protein levels regulated by Not4p polyubiquitin-mediated degradation; regulates sporulation timing by extending period of active transcription; regulates rDNA silencing; human homolog is JARID1C 1 2 3 4 5 6 7
EC Number