STE24 / YJR117W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene in reference strain S288C; null mutant exhibits reduced mating and pheromone, sensitivity to Ni2+, and proliferation of the nuclear inner membrane; in large-scale studies, null mutant shows increased competitive fitness, decreased mating response and anaerobic growth, and abnormal secretion of Kar2p; overexpression in the Sigma1278b genetic background confers enhanced pseudohyphal growth; null mutant displays altered resistance to a variety of chemicals

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

54 entries for 24 phenotypes

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources