Phenotype Help

BIR1 / YJR089W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Essential gene in some strain backgrounds and non-essential in others; deletion and overexpression result in elevated rates of chromosome loss and missegregation; conditional mutant has a chromosome biorientation defect; heterozygous null mutant has a growth defect, displays elevated polyploidy and grossly altered morphology; CDK phosphorylation site mutant has short anaphase spindles and is unable to properly localize Cbf2p/Ndc10p to the anaphase spindle and midzone; conditional mutant mislocalizes both Bub1p and Ipl1p, and has decreased levels of Pds1p; conditional mutant displays increased oxidative stress-induced apoptosis, while overexpression reduces apoptosis; overexpression results in a growth advantage; diploid null mutant has delayed and inefficient sporulation while the haploid null mutant has a severe spore germination defect; homozygous diploid null mutant forms pseudohyphal structures in sporulation media


A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.