Literature Help
GEA1 / YJR031C Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Sornlek W, et al. (2024) Identification of genes associated with the high-temperature fermentation trait in the Saccharomyces cerevisiae natural isolate BCC39850. Arch Microbiol 206(10):391 PMID:39230763
- Sabido-Bozo S, et al. (2021) The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection. Int J Mol Sci 22(1) PMID:33401608
- Gustafson MA and Fromme JC (2017) Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments. Mol Biol Cell 28(25):3660-3671 PMID:28978742
- Becker B, et al. (2016) Yeast Reporter Assay to Identify Cellular Components of Ricin Toxin A Chain Trafficking. Toxins (Basel) 8(12) PMID:27929418
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Ackema KB, et al. (2014) The small GTPase Arf1 modulates mitochondrial morphology and function. EMBO J 33(22):2659-75 PMID:25190516
- Mioka T, et al. (2014) Asymmetric distribution of phosphatidylserine is generated in the absence of phospholipid flippases in Saccharomyces cerevisiae. Microbiologyopen 3(5):803-21 PMID:25220349
- Novo M, et al. (2013) Genome-wide study of the adaptation of Saccharomyces cerevisiae to the early stages of wine fermentation. PLoS One 8(9):e74086 PMID:24040173
- Lin L, et al. (2011) The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases. Antimicrob Agents Chemother 55(1):246-54 PMID:20956596
- Chen KY, et al. (2010) Syt1p promotes activation of Arl1p at the late Golgi to recruit Imh1p. J Cell Sci 123(Pt 20):3478-89 PMID:20841378
- Gloor Y, et al. (2010) Interaction between Sec7p and Pik1p: the first clue for the regulation of a coincidence detection signal. Eur J Cell Biol 89(8):575-83 PMID:20434792
- van der Vaart A, et al. (2010) Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae. Mol Biol Cell 21(13):2270-84 PMID:20444982
- Deng Y, et al. (2009) A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor. EMBO Rep 10(1):58-64 PMID:19039328
- Park SK, et al. (2005) Mutations in a highly conserved region of the Arf1p activator GEA2 block anterograde Golgi transport but not COPI recruitment to membranes. Mol Biol Cell 16(8):3786-99 PMID:15930122
- Chantalat S, et al. (2003) A novel Golgi membrane protein is a partner of the ARF exchange factors Gea1p and Gea2p. Mol Biol Cell 14(6):2357-71 PMID:12808035
- Zakrzewska E, et al. (2003) A role for GEA1 and GEA2 in the organization of the actin cytoskeleton in Saccharomyces cerevisiae. Genetics 165(3):985-95 PMID:14668359
- Peyroche A, et al. (2001) The ARF exchange factors Gea1p and Gea2p regulate Golgi structure and function in yeast. J Cell Sci 114(Pt 12):2241-53 PMID:11493664
- Spang A, et al. (2001) The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol Biol Cell 12(4):1035-45 PMID:11294905
- Jones S, et al. (1999) Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers. Genetics 152(4):1543-56 PMID:10430582
- Peyroche A, et al. (1999) Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain. Mol Cell 3(3):275-85 PMID:10198630
- Peyroche A, et al. (1996) Nucleotide exchange on ARF mediated by yeast Gea1 protein. Nature 384(6608):479-81 PMID:8945477
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
Reset
Click on a gene or a paper to go to its specific page within SGD. Drag any of the gene or paper objects around
within the visualization for easier viewing and click “Reset” to automatically redraw the diagram.
Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Muccini A and Fromme JC (2022) Structural basis for the activation of Arf1 at the Golgi complex by its GEF Gea2. FASEB J 36 Suppl 1.
- Muccini AJ, et al. (2022) Structural basis for activation of Arf1 at the Golgi complex. Cell Rep 40(9):111282 PMID:36044848
- Purkanti R and Thattai M (2022) Genome doubling enabled the expansion of yeast vesicle traffic pathways. Sci Rep 12(1):11213 PMID:35780185
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Hsu JW, et al. (2015) Snf1/AMP-activated protein kinase activates Arf3p to promote invasive yeast growth via a non-canonical GEF domain. Nat Commun 6:7840 PMID:26198097
- Tun NM, et al. (2013) Disulfide stress-induced aluminium toxicity: molecular insights through genome-wide screening of Saccharomyces cerevisiae. Metallomics 5(8):1068-75 PMID:23832094
- Gloor Y, et al. (2012) Co-regulation of the arf-activation cycle and phospholipid-signaling during golgi maturation. Commun Integr Biol 5(1):12-5 PMID:22482002
- Richardson BC, et al. (2012) The Sec7 Arf-GEF is recruited to the trans-Golgi network by positive feedback. Dev Cell 22(4):799-810 PMID:22516198
- Ambroset C, et al. (2011) Deciphering the molecular basis of wine yeast fermentation traits using a combined genetic and genomic approach. G3 (Bethesda) 1(4):263-81 PMID:22384338
- Chen S, et al. (2011) Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic. Mol Biol Cell 22(19):3634-44 PMID:21813735
- Aucher W, et al. (2010) A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Mol Cell Proteomics 9(12):2745-59 PMID:20733106
- Qi Y, et al. (2008) Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions. Genome Res 18(12):1991-2004 PMID:18832443
- Steigele S, et al. (2007) Comparative analysis of structured RNAs in S. cerevisiae indicates a multitude of different functions. BMC Biol 5:25 PMID:17577407
- Bell AW, et al. (2001) Proteomics characterization of abundant Golgi membrane proteins. J Biol Chem 276(7):5152-65 PMID:11042173
- Peyroche A and Jackson CL (2001) Functional analysis of ADP-ribosylation factor (ARF) guanine nucleotide exchange factors Gea1p and Gea2p in yeast. Methods Enzymol 329:290-300 PMID:11210546
- Chardin P, et al. (1996) A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains. Nature 384(6608):481-4 PMID:8945478
Reviews
No reviews curated.
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- van der Vaart A, et al. (2010) Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae. Mol Biol Cell 21(13):2270-84 PMID:20444982
- Zakrzewska E, et al. (2003) A role for GEA1 and GEA2 in the organization of the actin cytoskeleton in Saccharomyces cerevisiae. Genetics 165(3):985-95 PMID:14668359
- Peyroche A, et al. (2001) The ARF exchange factors Gea1p and Gea2p regulate Golgi structure and function in yeast. J Cell Sci 114(Pt 12):2241-53 PMID:11493664
- Spang A, et al. (2001) The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol Biol Cell 12(4):1035-45 PMID:11294905
- Jones S, et al. (1999) Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers. Genetics 152(4):1543-56 PMID:10430582
- Peyroche A, et al. (1996) Nucleotide exchange on ARF mediated by yeast Gea1 protein. Nature 384(6608):479-81 PMID:8945477
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Sornlek W, et al. (2024) Identification of genes associated with the high-temperature fermentation trait in the Saccharomyces cerevisiae natural isolate BCC39850. Arch Microbiol 206(10):391 PMID:39230763
- Peyroche A, et al. (1999) Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain. Mol Cell 3(3):275-85 PMID:10198630
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Smurova K, et al. (2023) Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores. Nat Commun 14(1):3172 PMID:37263996
- Mattingly M, et al. (2022) Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion. Curr Biol 32(13):2884-2896.e6 PMID:35654035
- Sabido-Bozo S, et al. (2021) The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection. Int J Mol Sci 22(1) PMID:33401608
- Sanders E, et al. (2020) Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) 10(12):4359-4368 PMID:33115720
- Espinosa-Cantú A, et al. (2018) Protein Moonlighting Revealed by Noncatalytic Phenotypes of Yeast Enzymes. Genetics 208(1):419-431 PMID:29127264
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Gustafson MA and Fromme JC (2017) Regulation of Arf activation occurs via distinct mechanisms at early and late Golgi compartments. Mol Biol Cell 28(25):3660-3671 PMID:28978742
- Makrantoni V, et al. (2017) A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis. G3 (Bethesda) 7(9):3203-3215 PMID:28754723
- Sturm M, et al. (2017) Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly. Nat Commun 8(1):2213 PMID:29263326
- Babour A, et al. (2016) The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell 167(5):1201-1214.e15 PMID:27863241
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Lakshminarasimhan M, et al. (2016) Proteomic and Genomic Analyses of the Rvb1 and Rvb2 Interaction Network upon Deletion of R2TP Complex Components. Mol Cell Proteomics 15(3):960-74 PMID:26831523
- Chapa-Y-Lazo B and Ayscough KR (2014) Apm4, the mu subunit of yeast AP-2 interacts with Pkc1, and mutation of the Pkc1 consensus phosphorylation site Thr176 inhibits AP-2 recruitment to endocytic sites. Commun Integr Biol 7:e28522 PMID:25346786
- Surma MA, et al. (2013) A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Mol Cell 51(4):519-30 PMID:23891562
- Tsai PC, et al. (2013) Arl1p regulates spatial membrane organization at the trans-Golgi network through interaction with Arf-GEF Gea2p and flippase Drs2p. Proc Natl Acad Sci U S A 110(8):E668-77 PMID:23345439
- Wang Y, et al. (2012) Coiled-coil networking shapes cell molecular machinery. Mol Biol Cell 23(19):3911-22 PMID:22875988
- Chen S, et al. (2011) Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic. Mol Biol Cell 22(19):3634-44 PMID:21813735
- Aucher W, et al. (2010) A strategy for interaction site prediction between phospho-binding modules and their partners identified from proteomic data. Mol Cell Proteomics 9(12):2745-59 PMID:20733106
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Batisse J, et al. (2009) Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem 284(50):34911-7 PMID:19840948
- Deng Y, et al. (2009) A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor. EMBO Rep 10(1):58-64 PMID:19039328
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 PMID:16269340
- Chantalat S, et al. (2003) A novel Golgi membrane protein is a partner of the ARF exchange factors Gea1p and Gea2p. Mol Biol Cell 14(6):2357-71 PMID:12808035
- Zakrzewska E, et al. (2003) A role for GEA1 and GEA2 in the organization of the actin cytoskeleton in Saccharomyces cerevisiae. Genetics 165(3):985-95 PMID:14668359
- Peyroche A, et al. (2001) The ARF exchange factors Gea1p and Gea2p regulate Golgi structure and function in yeast. J Cell Sci 114(Pt 12):2241-53 PMID:11493664
- Spang A, et al. (2001) The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol Biol Cell 12(4):1035-45 PMID:11294905
- Jones S, et al. (1999) Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers. Genetics 152(4):1543-56 PMID:10430582
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Coey CT and Clark DJ (2022) A systematic genome-wide account of binding sites for the model transcription factor Gcn4. Genome Res 32(2):367-377 PMID:34916251
- Mondeel TDGA, et al. (2019) ChIP-exo analysis highlights Fkh1 and Fkh2 transcription factors as hubs that integrate multi-scale networks in budding yeast. Nucleic Acids Res 47(15):7825-7841 PMID:31299083
- Johnson AJ, et al. (2016) Revelation of molecular basis for chromium toxicity by phenotypes of Saccharomyces cerevisiae gene deletion mutants. Metallomics 8(5):542-50 PMID:27146641
- Mülleder M, et al. (2016) Functional Metabolomics Describes the Yeast Biosynthetic Regulome. Cell 167(2):553-565.e12 PMID:27693354
- Ostrow AZ, et al. (2014) Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics. PLoS One 9(2):e87647 PMID:24504085
- Choy JS, et al. (2013) Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability. Mol Biol Cell 24(17):2753-63 PMID:23825022
- Lis M, et al. (2013) Chemical genomic screening of a Saccharomyces cerevisiae genomewide mutant collection reveals genes required for defense against four antimicrobial peptides derived from proteins found in human saliva. Antimicrob Agents Chemother 57(2):840-7 PMID:23208710
- Michaillat L and Mayer A (2013) Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PLoS One 8(2):e54160 PMID:23383298
- Novo M, et al. (2013) Genome-wide study of the adaptation of Saccharomyces cerevisiae to the early stages of wine fermentation. PLoS One 8(9):e74086 PMID:24040173
- Tun NM, et al. (2013) Disulfide stress-induced aluminium toxicity: molecular insights through genome-wide screening of Saccharomyces cerevisiae. Metallomics 5(8):1068-75 PMID:23832094
- Teng X, et al. (2011) Gene-dependent cell death in yeast. Cell Death Dis 2(8):e188 PMID:21814286
- Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61 PMID:21341307
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Marston AL, et al. (2004) A genome-wide screen identifies genes required for centromeric cohesion. Science 303(5662):1367-70 PMID:14752166
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549