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SOP4 / YJL192C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
EMC7 2
Feature Type
ORF , Verified
Description
ER-membrane protein; subunit of evolutionarily conserved EMC (Endoplasmic Reticulum Membrane Complex) implicated in ERAD (ER-associated degradation) and proper assembly of multi-pass transmembrane (TM) proteins; EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein Tom5 of TOM (Translocase of the Mitochondrial Outer Membrane) complex; suppressor of pma1-7, deletion of SOP4 slows down export of wild-type Pma1p and Pma1-7 from the ER 1 2 3

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