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SET2 / YJL168C Sequence
Sequences and genome annotation information for Reference Strain S288C and a select set of
Alternative References.
- Aliases
-
EZL1
,
KMT3
10
- Protein Product
-
histone methyltransferase SET2
- Feature Type
- ORF
, Verified
- Description
-
Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia
2
3
4
5
7
8
9
- EC Number
-
2.1.1.359