Phenotype Help

AIM23 / YJL131C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant displays is unable to grow on non-fermentable carbons sources, and displays reduced growth in anaerobic conditions; null mutant displays an increased frequency of spontaneous mitochondrial genome loss; null mutant is sensitive to hyperosmotic stress and displays an enhanced ability to form biofilms

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

22 entries for 13 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
anaerobic growth: decreased
systematic mutation setnull
Allele: aim23-Δ
S288CTreatment: anoxia
Details: poor growth as indicated by measurements of colony size
Samanfar B, et al. (2013) PMID:23467670
biofilm formation: increased
systematic mutation setnull
Allele: aim23-Δ
S288CVandenbosch D, et al. (2013) PMID:24034557
competitive fitness: decreased
systematic mutation setnull
Allele: aim23-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
competitive growth overexpressionS288CDetails: decreased abundance within the barFLEX overexpression collection arrayed after 20 generations of pooled growth
Douglas AC, et al. (2012) PMID:23050238
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: aim23-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.002
Breslow DK, et al. (2008) PMID:18622397
hyperosmotic stress resistance: decreased
systematic mutation setnull
Allele: aim23-Δ
S288C1 M sodium chlorideYoshikawa K, et al. (2009) PMID:19054128
metal resistance: increased
systematic mutation set null
Allele: aim23-Δ
S288C3.9 mM gadolinium(3+)Treatment: gadolinium (III) chloride hexahydrate, 3.9 mM
Details: medium resistance; confirmed by serial dilution spot assays on 4.0 mM Gd
Grosjean N, et al. (2023) PMID:37630673
mitochondrial genome maintenance: abnormal
large-scale surveynull
Allele: aim23-Δ
S288CDetails: increased frequency of spontaneous mitochondrial genome loss
Hess DC, et al. (2009) PMID:19300474
resistance to chemicals: decreased
systematic mutation setnull
Allele: aim23-Δ
S288C8% ethanolYoshikawa K, et al. (2009) PMID:19054128
resistance to chemicals: decreased
systematic mutation setnull
Allele: aim23-Δ
S288C16% methanolAuesukaree C, et al. (2009) PMID:19638689
Showing 1 to 10 of 22 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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