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LSM1 / YJL124C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
SPB8
Feature Type
ORF , Verified
Description
Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress 2 3 4 5 6 7

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