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ASF1 / YJL115W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
CIA1 26
Protein Product
nucleosome assembly factor ASF1
Feature Type
ORF , Verified
Description
Nucleosome assembly factor; involved in chromatin assembly, disassembly; required for recovery after DSB repair; role in H3K56 acetylation required for expression homeostasis, buffering mRNA synthesis rate against gene dosage changes in S phase; anti-silencing protein, derepresses silent loci when overexpressed; role in regulating Ty1 transposition; relocalizes to cytosol under hypoxia; growth defect of asf1 null is functionally complemented by either human ASF1A or ASF1B 2 3 4 5 6 7 9 10 11

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