Phenotype Help

CHS6 / YJL099W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant has strong defect in delivering chitin synthase to plasma membrane that leads to decreased chitin content in cell wall; null mutant displays increased resistance to Calcofluor White and lithium, and increased heat sensitivity; in systematic studies null mutants show elevated resistance to camptothecin, fenpropimorph, fluconazole, tunicamycin, bleomycin and MMS

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

50 entries for 14 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
biofilm formation: increased
systematic mutation setnull
Allele: chs6-Δ
S288CVandenbosch D, et al. (2013) PMID:24034557
chitin deposition: decreased
systematic mutation setnull
Allele: chs6-Δ
S288CDetails: fluorescent Calcofluor white binding
Lam KK, et al. (2006) PMID:16818716
chitin deposition: decreased
systematic mutation setnull
Allele: chs6-Δ
S288CDetails: Chitin level (nmole GlcNAc/mg dry weight): 2.4
Lesage G, et al. (2005) PMID:15715908
chitin deposition: decreased
classical geneticsreduction of functionOtherBulawa CE (1992) PMID:1532231
chitin deposition: decreased
classical geneticsnull
Allele: chs6-Δ
S288CDetails: decreased calcofluor white staining of the cell wall
Trautwein M, et al. (2006) PMID:16498409
chronological lifespan: decreased
competitive growth

competitive survival of mixed stationary phase co-cultures

null
Allele: chs6-Δ
S288CGaray E, et al. (2014) PMID:24586198
competitive fitness: decreased
systematic mutation set

fitness profiling after 15 generations

null
Allele: chs6-Δ
S288CMedia: alkaline conditions, pH 8
Giaever G, et al. (2002) PMID:12140549
competitive fitness: decreased
systematic mutation setnull
Allele: chs6-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: chs6-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: chs6-Δ
S288CMedia: YPD
Qian W, et al. (2012) PMID:23103169
Showing 1 to 10 of 50 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


Resources