Literature Help
PHS1 / YJL097W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Hammond N, et al. (2023) Identification and characterization of protein interactions with the major Niemann-Pick type C disease protein in yeast reveals pathways of therapeutic potential. Genetics 225(1) PMID:37440478
- Laurent JM, et al. (2020) Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs. PLoS Biol 18(5):e3000627 PMID:32421706
- Martínez-Montañés F, et al. (2016) Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether. J Lipid Res 57(11):2040-2050 PMID:27561298
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Hamza A, et al. (2015) Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. Genetics 201(3):1263-74 PMID:26354769
- Ianiri G, et al. (2014) Phs1 and the synthesis of very long chain Fatty acids are required for ballistospore formation. PLoS One 9(8):e105147 PMID:25148260
- Aung HW, et al. (2013) Revising the Representation of Fatty Acid, Glycerolipid, and Glycerophospholipid Metabolism in the Consensus Model of Yeast Metabolism. Ind Biotechnol (New Rochelle N Y) 9(4):215-228 PMID:24678285
- Matsumoto R, et al. (2013) Organelle acidification is important for localisation of vacuolar proteins in Saccharomyces cerevisiae. Protoplasma 250(6):1283-93 PMID:23708375
- Obara K, et al. (2013) Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids. J Lipid Res 54(3):831-842 PMID:23325927
- Yazawa T, et al. (2013) Identification of residues important for the catalysis, structure maintenance, and substrate specificity of yeast 3-hydroxyacyl-CoA dehydratase Phs1. FEBS Lett 587(6):804-9 PMID:23416297
- Bach L, et al. (2008) The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development. Proc Natl Acad Sci U S A 105(38):14727-31 PMID:18799749
- Kihara A, et al. (2008) Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation. J Biol Chem 283(17):11199-209 PMID:18272525
- Denic V and Weissman JS (2007) A molecular caliper mechanism for determining very long-chain fatty acid length. Cell 130(4):663-77 PMID:17719544
- Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 PMID:16943325
- Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 PMID:16269340
- Bellec Y, et al. (2002) Pasticcino2 is a protein tyrosine phosphatase-like involved in cell proliferation and differentiation in Arabidopsis. Plant J 32(5):713-22 PMID:12472687
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Morineau C, et al. (2016) Dual Fatty Acid Elongase Complex Interactions in Arabidopsis. PLoS One 11(9):e0160631 PMID:27583779
- Fröhlich F, et al. (2015) The GARP complex is required for cellular sphingolipid homeostasis. Elife 4 PMID:26357016
- Gallego O, et al. (2010) A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol Syst Biol 6:430 PMID:21119626
- Ma M and Liu LZ (2010) Quantitative transcription dynamic analysis reveals candidate genes and key regulators for ethanol tolerance in Saccharomyces cerevisiae. BMC Microbiol 10:169 PMID:20537179
- Ben-Aroya S, et al. (2008) Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell 30(2):248-58 PMID:18439903
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Ikeda M, et al. (2008) Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis. FEBS Lett 582(16):2435-40 PMID:18554506
- Mirzaei H and Regnier F (2006) Enrichment of carbonylated peptides using Girard P reagent and strong cation exchange chromatography. Anal Chem 78(3):770-8 PMID:16448050
- Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 PMID:16155567
- Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 PMID:14690591
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
- Mallet L, et al. (2000) Functional cloning of the adenylate cyclase gene of Candida albicans in Saccharomyces cerevisiae within a genomic fragment containing five other genes, including homologues of CHS6 and SAP185. Yeast 16(10):959-66 PMID:10870107
- Zhang CT and Wang J (2000) Recognition of protein coding genes in the yeast genome at better than 95% accuracy based on the Z curve. Nucleic Acids Res 28(14):2804-14 PMID:10908339
- Entian KD, et al. (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702 PMID:10628851
Reviews
No reviews curated.
Download References (.nbib)
- Tani M (2024) Biological Importance of Complex Sphingolipids and Their Structural Diversity in Budding Yeast Saccharomyces cerevisiae. Int J Mol Sci 25(22) PMID:39596489
- Erdbrügger P and Fröhlich F (2020) The role of very long chain fatty acids in yeast physiology and human diseases. Biol Chem 402(1):25-38 PMID:33544487
- de Kroon AI, et al. (2013) Checks and balances in membrane phospholipid class and acyl chain homeostasis, the yeast perspective. Prog Lipid Res 52(4):374-94 PMID:23631861
- Henry SA, et al. (2012) Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics 190(2):317-49 PMID:22345606
- Kihara A (2012) Very long-chain fatty acids: elongation, physiology and related disorders. J Biochem 152(5):387-95 PMID:22984005
- Breker M and Schuldiner M (2009) Explorations in topology-delving underneath the surface of genetic interaction maps. Mol Biosyst 5(12):1473-81 PMID:19763324
- Dickson RC (2008) Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast. J Lipid Res 49(5):909-21 PMID:18296751
- Thevissen K, et al. (2005) Fungal sphingolipids as targets for the development of selective antifungal therapeutics. Curr Drug Targets 6(8):923-8 PMID:16375675
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Yofe I, et al. (2016) One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nat Methods 13(4):371-378 PMID:26928762
- Matsumoto R, et al. (2013) Organelle acidification is important for localisation of vacuolar proteins in Saccharomyces cerevisiae. Protoplasma 250(6):1283-93 PMID:23708375
- Yazawa T, et al. (2013) Identification of residues important for the catalysis, structure maintenance, and substrate specificity of yeast 3-hydroxyacyl-CoA dehydratase Phs1. FEBS Lett 587(6):804-9 PMID:23416297
- Kihara A, et al. (2008) Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation. J Biol Chem 283(17):11199-209 PMID:18272525
- Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 PMID:16943325
- Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 PMID:14690591
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Disease Literature
Paper(s) associated with one or more pieces of disease evidence in SGD, as found on the Disease page.
No disease literature curated.
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Gordon MR, et al. (2023) Suppression of chromosome instability by targeting a DNA helicase in budding yeast. Mol Biol Cell 34(1):ar3 PMID:36350688
- Hammond N, et al. (2023) Identification and characterization of protein interactions with the major Niemann-Pick type C disease protein in yeast reveals pathways of therapeutic potential. Genetics 225(1) PMID:37440478
- Sanders E, et al. (2020) Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1. G3 (Bethesda) 10(12):4359-4368 PMID:33115720
- Bommi JR, et al. (2019) Meiosis-specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope. Genes Cells 24(1):94-106 PMID:30417519
- Kuzmin E, et al. (2018) Systematic analysis of complex genetic interactions. Science 360(6386) PMID:29674565
- Mount HO, et al. (2018) Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs. PLoS Genet 14(4):e1007319 PMID:29702647
- Lapointe CP, et al. (2017) Architecture and dynamics of overlapped RNA regulatory networks. RNA 23(11):1636-1647 PMID:28768715
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Lapointe CP, et al. (2015) Protein-RNA networks revealed through covalent RNA marks. Nat Methods 12(12):1163-70 PMID:26524240
- Obara K, et al. (2013) Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids. J Lipid Res 54(3):831-842 PMID:23325927
- Surma MA, et al. (2013) A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Mol Cell 51(4):519-30 PMID:23891562
- van Pel DM, et al. (2013) Saccharomyces cerevisiae genetics predicts candidate therapeutic genetic interactions at the mammalian replication fork. G3 (Bethesda) 3(2):273-82 PMID:23390603
- Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol 195(2):323-40 PMID:21987634
- Stirling PC, et al. (2011) The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components. PLoS Genet 7(4):e1002057 PMID:21552543
- Van Zeebroeck G, et al. (2011) A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2. PLoS One 6(9):e24275 PMID:21912684
- Hasegawa Y, et al. (2008) Distinct roles for Khd1p in the localization and expression of bud-localized mRNAs in yeast. RNA 14(11):2333-47 PMID:18805955
- Kihara A, et al. (2008) Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation. J Biol Chem 283(17):11199-209 PMID:18272525
- Yu H, et al. (2008) High-quality binary protein interaction map of the yeast interactome network. Science 322(5898):104-10 PMID:18719252
- Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 PMID:16155567
- Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 PMID:16269340
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Functional Complementation Annotations Literature
Paper(s) associated with one or more pieces of functional complementation annotations evidence in SGD.
No functional complementation annotations literature curated.
Download References (.nbib)
- Laurent JM, et al. (2020) Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs. PLoS Biol 18(5):e3000627 PMID:32421706
- Hamza A, et al. (2015) Complementation of Yeast Genes with Human Genes as an Experimental Platform for Functional Testing of Human Genetic Variants. Genetics 201(3):1263-74 PMID:26354769
- Ikeda M, et al. (2008) Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis. FEBS Lett 582(16):2435-40 PMID:18554506
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Forster DT, et al. (2022) BIONIC: biological network integration using convolutions. Nat Methods 19(10):1250-1261 PMID:36192463
- Ohnuki S and Ohya Y (2018) High-dimensional single-cell phenotyping reveals extensive haploinsufficiency. PLoS Biol 16(5):e2005130 PMID:29768403
- Fröhlich F, et al. (2015) The GARP complex is required for cellular sphingolipid homeostasis. Elife 4 PMID:26357016
- Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61 PMID:21341307
- Ben-Aroya S, et al. (2008) Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell 30(2):248-58 PMID:18439903
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Hu Z, et al. (2007) Genetic reconstruction of a functional transcriptional regulatory network. Nat Genet 39(5):683-7 PMID:17417638
- Mendiratta G, et al. (2006) The DNA-binding domain of the yeast Spt10p activator includes a zinc finger that is homologous to foamy virus integrase. J Biol Chem 281(11):7040-8 PMID:16415340
- Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 PMID:16943325
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549