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COQ6 / YGR255C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
putative N,N-dimethylaniline monooxygenase COQ6
Feature Type
ORF , Verified
Description
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis; responsible for hydroxylation at position C5 and deamination at C4 during ubiquinone (Coenzyme Q) biosynthesis; localizes to matrix face of mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human homolog COQ6 can complement yeast null mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS) 1 2 3 4 5

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