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GCN5 / YGR252W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

ADA4 31 , SWI9 32 , AAS104 33 , KAT2 34
Protein Product
histone acetyltransferase GCN5
Feature Type
ORF , Verified
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation 2 3 5 6 7 8 9
EC Number