CLB6 / YGR109C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene in reference strain S288C; null mutation accelerates progression through START and G2/M phase transition, which leads to small cell size; overexpression slows down G2 phase progression and increases chromosome loss; in systematic studies null mutants are sensitive to cycloheximide and mycophenolic acid, but resistant to hydroxyurea, fenpropimorph, camptothecin, tunicamycin, bleomycin

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

37 entries for 22 phenotypes

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources