Literature Help
ROM1 / YGR070W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
- Unique References
- 99
- Aliases
-
SKC1
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Watanabe D, et al. (2023) Rational design of alcoholic fermentation targeting extracellular carbon. NPJ Sci Food 7(1):37 PMID:37479699
- Zeng L, et al. (2022) Transcriptomic analysis of formic acid stress response in Saccharomyces cerevisiae. World J Microbiol Biotechnol 38(2):34 PMID:34989900
- Babele PK, et al. (2018) Zinc oxide nanoparticles induce toxicity by affecting cell wall integrity pathway, mitochondrial function and lipid homeostasis in Saccharomyces cerevisiae. Chemosphere 213:65-75 PMID:30212720
- Prosser DC, et al. (2015) α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. J Cell Sci 128(22):4220-34 PMID:26459639
- Miyamoto M, et al. (2012) The high-osmolarity glycerol- and cell wall integrity-MAP kinase pathways of Saccharomyces cerevisiae are involved in adaptation to the action of killer toxin HM-1. Yeast 29(11):475-85 PMID:23065846
- Prosser DC, et al. (2011) Existence of a novel clathrin-independent endocytic pathway in yeast that depends on Rho1 and formin. J Cell Biol 195(4):657-71 PMID:22065638
- Wang Y, et al. (2008) Down-regulation of Pkc1-mediated signaling by the deubiquitinating enzyme Ubp3. J Biol Chem 283(4):1954-61 PMID:17986446
- Quan X, et al. (2007) The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. Biochim Biophys Acta 1773(7):1052-61 PMID:17544521
- Claret S, et al. (2005) The Rgd1p Rho GTPase-activating protein and the Mid2p cell wall sensor are required at low pH for protein kinase C pathway activation and cell survival in Saccharomyces cerevisiae. Eukaryot Cell 4(8):1375-86 PMID:16087742
- Marcoux N, et al. (2000) Suppression of the profilin-deficient phenotype by the RHO2 signaling pathway in Saccharomyces cerevisiae. Genetics 156(2):579-92 PMID:11014808
- Ozaki K, et al. (1996) Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 15(9):2196-207 PMID:8641285
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Li X, et al. (2016) Different Regulations of ROM2 and LRG1 Expression by Ccr4, Pop2, and Dhh1 in the Saccharomyces cerevisiae Cell Wall Integrity Pathway. mSphere 1(5) PMID:27704052
- Prosser DC, et al. (2016) Applications of pHluorin for Quantitative, Kinetic and High-throughput Analysis of Endocytosis in Budding Yeast. J Vis Exp PMID:27805610
- Jovičić A, et al. (2015) Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nat Neurosci 18(9):1226-9 PMID:26308983
- Soria PS, et al. (2014) Functional divergence for every paralog. Mol Biol Evol 31(4):984-92 PMID:24451325
- Onishi M, et al. (2013) Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis. J Cell Biol 202(2):311-29 PMID:23878277
- Krause SA, et al. (2012) Functional specialisation of yeast Rho1 GTP exchange factors. J Cell Sci 125(Pt 11):2721-31 PMID:22344253
- Ito W, et al. (2011) RNA-binding protein Khd1 and Ccr4 deadenylase play overlapping roles in the cell wall integrity pathway in Saccharomyces cerevisiae. Eukaryot Cell 10(10):1340-7 PMID:21873511
- Jung PP, et al. (2011) Ploidy influences cellular responses to gross chromosomal rearrangements in Saccharomyces cerevisiae. BMC Genomics 12:331 PMID:21711526
- Matia-González AM and Rodríguez-Gabriel MA (2011) Slt2 MAPK pathway is essential for cell integrity in the presence of arsenate. Yeast 28(1):9-17 PMID:20737431
- Rodríguez-Quiñones JF and Rodríguez-Medina JR (2009) Differential gene expression signatures for cell wall integrity found in chitin synthase II (chs2Delta) and myosin II (myo1Delta) deficient cytokinesis mutants of Saccharomyces cerevisiae. BMC Res Notes 2:87 PMID:19426543
- Yoshida S, et al. (2009) Mechanisms for concentrating Rho1 during cytokinesis. Genes Dev 23(7):810-23 PMID:19339687
- Bermejo C, et al. (2008) The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress. Mol Biol Cell 19(3):1113-24 PMID:18184748
- Zhao XM, et al. (2008) Uncovering signal transduction networks from high-throughput data by integer linear programming. Nucleic Acids Res 36(9):e48 PMID:18411207
- Lockshon D, et al. (2007) The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function. Genetics 175(1):77-91 PMID:17151231
- Coll PM, et al. (2003) Gef1p, a new guanine nucleotide exchange factor for Cdc42p, regulates polarity in Schizosaccharomyces pombe. Mol Biol Cell 14(1):313-23 PMID:12529446
- Zhang W, et al. (2003) Microarray analyses of the metabolic responses of Saccharomyces cerevisiae to organic solvent dimethyl sulfoxide. J Ind Microbiol Biotechnol 30(1):57-69 PMID:12545388
- Kumar A and Paietta JV (1998) An additional role for the F-box motif: gene regulation within the Neurospora crassa sulfur control network. Proc Natl Acad Sci U S A 95(5):2417-22 PMID:9482900
- Schultz J, et al. (1998) SMART, a simple modular architecture research tool: identification of signaling domains. Proc Natl Acad Sci U S A 95(11):5857-64 PMID:9600884
Reviews
No reviews curated.
Download References (.nbib)
- Feng T, et al. (2025) Mechanisms and Strategies for Engineering Oxidative Stress Resistance in Saccharomyces cerevisiae. Chem Bio Eng 2(7):409-422 PMID:40735014
- González-Rubio G, et al. (2022) Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity. J Fungi (Basel) 8(4) PMID:35448599
- Li B, et al. (2022) Response mechanisms of Saccharomyces cerevisiae to the stress factors present in lignocellulose hydrolysate and strategies for constructing robust strains. Biotechnol Biofuels Bioprod 15(1):28 PMID:35292082
- Ribeiro RA, et al. (2022) The cell wall and the response and tolerance to stresses of biotechnological relevance in yeasts. Front Microbiol 13:953479 PMID:35966694
- Cansado J, et al. (2021) The Fission Yeast Cell Integrity Pathway: A Functional Hub for Cell Survival upon Stress and Beyond. J Fungi (Basel) 8(1) PMID:35049972
- Schlarmann P, et al. (2021) Membrane Contact Sites in Yeast: Control Hubs of Sphingolipid Homeostasis. Membranes (Basel) 11(12) PMID:34940472
- de Oliveira HC, et al. (2021) Cell Wall Integrity Pathway Involved in Morphogenesis, Virulence and Antifungal Susceptibility in Cryptococcus neoformans. J Fungi (Basel) 7(10) PMID:34682253
- Van Drogen F, et al. (2020) Crosstalk and spatiotemporal regulation between stress-induced MAP kinase pathways and pheromone signaling in budding yeast. Cell Cycle 19(14):1707-1715 PMID:32552303
- Lee J, et al. (2019) Stressing out or stressing in: intracellular pathways for SAPK activation. Curr Genet 65(2):417-421 PMID:30377756
- Yoshimi A, et al. (2017) Function and Biosynthesis of Cell Wall α-1,3-Glucan in Fungi. J Fungi (Basel) 3(4) PMID:29371579
- van Leeuwen J, et al. (2017) Mapping a diversity of genetic interactions in yeast. Curr Opin Syst Biol 6:14-21 PMID:30505984
- Meitinger F and Palani S (2016) Actomyosin ring driven cytokinesis in budding yeast. Semin Cell Dev Biol 53:19-27 PMID:26845196
- Hamann T (2015) The plant cell wall integrity maintenance mechanism--a case study of a cell wall plasma membrane signaling network. Phytochemistry 112:100-9 PMID:25446233
- Martin SG and Arkowitz RA (2014) Cell polarization in budding and fission yeasts. FEMS Microbiol Rev 38(2):228-53 PMID:24354645
- Bi E and Park HO (2012) Cell polarization and cytokinesis in budding yeast. Genetics 191(2):347-87 PMID:22701052
- Prosser DC and Wendland B (2012) Conserved roles for yeast Rho1 and mammalian RhoA GTPases in clathrin-independent endocytosis. Small GTPases 3(4):229-35 PMID:23238351
- Heinisch JJ and Dufrêne YF (2010) Is there anyone out there?--Single-molecule atomic force microscopy meets yeast genetics to study sensor functions. Integr Biol (Camb) 2(9):408-15 PMID:20648385
- Molina M, et al. (2010) Fine regulation of Saccharomyces cerevisiae MAPK pathways by post-translational modifications. Yeast 27(8):503-11 PMID:20641029
- Yakir-Tamang L and Gerst JE (2009) Phosphoinositides, exocytosis and polarity in yeast: all about actin? Trends Cell Biol 19(12):677-84 PMID:19818626
- Balasubramanian MK, et al. (2004) Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells. Curr Biol 14(18):R806-18 PMID:15380095
- Cabib E, et al. (2001) The yeast cell wall and septum as paradigms of cell growth and morphogenesis. J Biol Chem 276(23):19679-82 PMID:11309404
- Smits GJ, et al. (2001) Differential regulation of cell wall biogenesis during growth and development in yeast. Microbiology (Reading) 147(Pt 4):781-794 PMID:11283274
- Chant J (1999) Cell polarity in yeast. Annu Rev Cell Dev Biol 15:365-91 PMID:10611966
- Heinisch JJ, et al. (1999) The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae. Mol Microbiol 32(4):671-80 PMID:10361272
- Gustin MC, et al. (1998) MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62(4):1264-300 PMID:9841672
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Prosser DC, et al. (2011) Existence of a novel clathrin-independent endocytic pathway in yeast that depends on Rho1 and formin. J Cell Biol 195(4):657-71 PMID:22065638
- Ozaki K, et al. (1996) Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 15(9):2196-207 PMID:8641285
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Quan X, et al. (2007) The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. Biochim Biophys Acta 1773(7):1052-61 PMID:17544521
- Claret S, et al. (2005) The Rgd1p Rho GTPase-activating protein and the Mid2p cell wall sensor are required at low pH for protein kinase C pathway activation and cell survival in Saccharomyces cerevisiae. Eukaryot Cell 4(8):1375-86 PMID:16087742
- Ozaki K, et al. (1996) Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 15(9):2196-207 PMID:8641285
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Carey SB, et al. (2023) A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast. G3 (Bethesda) 13(1) PMID:36409020
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Xu F, et al. (2019) SSD1 suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications. PLoS Genet 15(8):e1008117 PMID:31465447
- Miller JE, et al. (2018) Genome-Wide Mapping of Decay Factor-mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4. G3 (Bethesda) 8(1):315-330 PMID:29158339
- Makrantoni V, et al. (2017) A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis. G3 (Bethesda) 7(9):3203-3215 PMID:28754723
- She R, et al. (2017) Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. Proc Natl Acad Sci U S A 114(14):3619-3624 PMID:28325876
- Zimmermann C, et al. (2017) Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28. G3 (Bethesda) 7(6):1753-1766 PMID:28428242
- Babour A, et al. (2016) The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Cell 167(5):1201-1214.e15 PMID:27863241
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Jonasson EM, et al. (2016) Zds1/Zds2-PP2ACdc55 complex specifies signaling output from Rho1 GTPase. J Cell Biol 212(1):51-61 PMID:26728856
- Li X, et al. (2016) Different Regulations of ROM2 and LRG1 Expression by Ccr4, Pop2, and Dhh1 in the Saccharomyces cerevisiae Cell Wall Integrity Pathway. mSphere 1(5) PMID:27704052
- Atencio D, et al. (2014) The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. G3 (Bethesda) 4(3):523-37 PMID:24470217
- Niepel M, et al. (2013) The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome. Mol Biol Cell 24(24):3920-38 PMID:24152732
- Onishi M, et al. (2013) Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis. J Cell Biol 202(2):311-29 PMID:23878277
- Krause SA, et al. (2012) Functional specialisation of yeast Rho1 GTP exchange factors. J Cell Sci 125(Pt 11):2721-31 PMID:22344253
- Bloom J, et al. (2011) Global analysis of Cdc14 phosphatase reveals diverse roles in mitotic processes. J Biol Chem 286(7):5434-45 PMID:21127052
- Ito W, et al. (2011) RNA-binding protein Khd1 and Ccr4 deadenylase play overlapping roles in the cell wall integrity pathway in Saccharomyces cerevisiae. Eukaryot Cell 10(10):1340-7 PMID:21873511
- Leung A, et al. (2011) Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat. Mol Biol Cell 22(15):2741-53 PMID:21680712
- Prosser DC, et al. (2011) Existence of a novel clathrin-independent endocytic pathway in yeast that depends on Rho1 and formin. J Cell Biol 195(4):657-71 PMID:22065638
- Breitkreutz A, et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6 PMID:20489023
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Batisse J, et al. (2009) Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem 284(50):34911-7 PMID:19840948
- Guo S, et al. (2009) A MAP kinase dependent feedback mechanism controls Rho1 GTPase and actin distribution in yeast. PLoS One 4(6):e6089 PMID:19564916
- Yoshida S, et al. (2009) Mechanisms for concentrating Rho1 during cytokinesis. Genes Dev 23(7):810-23 PMID:19339687
- Dixon SJ, et al. (2008) Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A 105(43):16653-8 PMID:18931302
- Wang Y, et al. (2008) Down-regulation of Pkc1-mediated signaling by the deubiquitinating enzyme Ubp3. J Biol Chem 283(4):1954-61 PMID:17986446
- Johansson MJ, et al. (2007) Association of yeast Upf1p with direct substrates of the NMD pathway. Proc Natl Acad Sci U S A 104(52):20872-7 PMID:18087042
- Tong AH, et al. (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science 295(5553):321-4 PMID:11743162
- Hosotani T, et al. (2001) PKC1, a protein kinase C homologue of Saccharomyces cerevisiae, participates in microtubule function through the yeast EB1 homologue, BIM1. Genes Cells 6(9):775-88 PMID:11554924
- Marcoux N, et al. (2000) Suppression of the profilin-deficient phenotype by the RHO2 signaling pathway in Saccharomyces cerevisiae. Genetics 156(2):579-92 PMID:11014808
- Ozaki K, et al. (1996) Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 15(9):2196-207 PMID:8641285
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Zhang F, et al. (2025) The Yeast Gsk-3 Kinase Mck1 Is Necessary for Cell Wall Remodeling in Glucose-Starved and Cell Wall-Stressed Cells. Int J Mol Sci 26(8) PMID:40332024
- Leutert M, et al. (2023) The regulatory landscape of the yeast phosphoproteome. Nat Struct Mol Biol 30(11):1761-1773 PMID:37845410
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Zhou X, et al. (2021) Cross-compartment signal propagation in the mitotic exit network. Elife 10 PMID:33481703
- MacGilvray ME, et al. (2020) Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses. J Proteome Res 19(8):3405-3417 PMID:32597660
- Swaney DL, et al. (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10(7):676-82 PMID:23749301
- Holt LJ, et al. (2009) Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325(5948):1682-6 PMID:19779198
- Albuquerque CP, et al. (2008) A multidimensional chromatography technology for in-depth phosphoproteome analysis. Mol Cell Proteomics 7(7):1389-96 PMID:18407956
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Guan M, et al. (2020) Molecular fingerprints of conazoles via functional genomic profiling of Saccharomyces cerevisiae. Toxicol In Vitro 69:104998 PMID:32919014
- Costa C, et al. (2015) New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae. PLoS One 10(8):e0135110 PMID:26267134
- Huang Z, et al. (2013) A functional variomics tool for discovering drug-resistance genes and drug targets. Cell Rep 3(2):577-85 PMID:23416056
- Michaillat L and Mayer A (2013) Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PLoS One 8(2):e54160 PMID:23383298
- Douglas AC, et al. (2012) Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda) 2(10):1279-89 PMID:23050238
- Pir P, et al. (2012) The genetic control of growth rate: a systems biology study in yeast. BMC Syst Biol 6:4 PMID:22244311
- Qian W, et al. (2012) The genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast. Cell Rep 2(5):1399-410 PMID:23103169
- Yu D, et al. (2012) High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome. BMC Genomics 13:623 PMID:23151179
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Breslow DK, et al. (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8 PMID:18622397
- Jin R, et al. (2008) Large-scale analysis of yeast filamentous growth by systematic gene disruption and overexpression. Mol Biol Cell 19(1):284-96 PMID:17989363
- Lockshon D, et al. (2007) The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function. Genetics 175(1):77-91 PMID:17151231
- Brown JA, et al. (2006) Global analysis of gene function in yeast by quantitative phenotypic profiling. Mol Syst Biol 2:2006.0001 PMID:16738548
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549
- Hanway D, et al. (2002) Previously uncharacterized genes in the UV- and MMS-induced DNA damage response in yeast. Proc Natl Acad Sci U S A 99(16):10605-10 PMID:12149442