THG1 / YGR024C Homology


Standard Name
THG1 1
Systematic Name
YGR024C
SGD ID
SGD:S000003256
Feature Type
ORF , Verified
Description
tRNAHis guanylyltransferase; adds a guanosine residue to the 5' end of tRNAH is after transcription and RNase P cleavage; can also catalyze reverse (3'-5') polymerization with certain substrates in a template-dependent reaction; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes 1 2 3
Name Description
tRNAHis Guanylyltransferase 1
Comparative Info

Homologs

Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.


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Species Gene ID Gene name Source

Functional Complementation

Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).

3 entries for 3 complements


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SpeciesGene IDStrain backgroundDirectionDetailsSourceReference
Homo sapiensHGNC:26053S288Cother complements yeastgrowth defect of thg1-Δ rescued by human THG1L, but clear growth defect was observed following expression of human p.Val55Ala THG1LSGDEdvardson S, et al. (2016)
PMID:27307223
Homo sapiensHGNC:26053S288Cother complements yeastHuman THG1L complements the inviability of the S. cerevisiae thg1 null mutant.SGDHamza A, et al. (2015)
PMID:26354769
Homo sapiensHGNC:26053S288Cother complements yeastHuman gene allows growth of the yeast haploid null mutant after sporulation of a heterozygous diploid.SGDKachroo AH, et al. (2015)
PMID:25999509
Showing 1 to 3 of 3 entries

Fungal Homologs

Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.


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Species Gene ID Gene name Description Source

External Identifiers

List of external identifiers for the protein from various database sources.

23 entries for 10 sources


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External IDSource
orf19.7063CGD
1670DIP
2.7.7.79ExPASy
CAA97007.1GenBank/EMBL/DDBJ
AAS56595.1GenBank/EMBL/DDBJ
AAZ22487.1GenBank/EMBL/DDBJ
Z72809GenBank/EMBL/DDBJ
AY558269GenBank/EMBL/DDBJ
DQ115389GenBank/EMBL/DDBJ
45270428GenBank/EMBL/DDBJ
Showing 1 to 10 of 23 entries

Resources