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COS12 / YGL263W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Feature Type
ORF , Verified
Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins 1 2 3

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