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HXK2 / YGL253W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
HEX1 , HKB , SCI2
Protein Product
hexokinase 2
Feature Type
ORF , Verified
Description
Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 2 3 4 5 6 7
Paralog
HXK1 5
EC Number
2.7.1.1

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