Sequence Help

BRR6 / YGL247W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Feature Type
ORF , Verified
Essential nuclear envelope integral membrane protein; interacts with chromatin, helping to maintain normal chromatin architecture and transcriptional regulation of certain loci at the nuclear envelope; interacts and functions with Apq12p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA nuclear export, and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; homologous to Brl1p 1 2 4 5