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SPT16 / YGL207W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

SSF1 , CDC68 20
Protein Product
chromatin-remodeling protein SPT16
Feature Type
ORF , Verified
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p); FACT associates with chromatin via interaction with Nhp6Ap and Nhp6Bp, and reorganizes nucleosomes to facilitate access to DNA by RNA and DNA polymerases; specifically required for diauxic shift-induced H2B deposition onto rDNA genes; mutations cause reduced nucleosome occupancy over highly transcribed regions; coregulates transcription with Mot1p through preinitiation complex assembly and nucleosome organization 2 3 4 5 6 7 8