Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.
8 entries for 7 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|
| adhesion: decreased | classical genetics | null Allele: rps26a-Δ | Sigma1278b | Details: absence of adhesive growth | Strittmatter AW, et al. (2006) PMID:16721598 | |
| cold sensitivity: increased | classical genetics | reduction of function Allele: rps26a-Y62A, P65A, K66A, Y68A, K70A rps26a-(Y62A, P65A, K66A, Y68A, K70A); mutations in conserved eukaryotic beta-strand region | Other | Details: increased 40S ribosomal subunits, suggesting decreased 80S ribosome assembly | Belyy A, et al. (2016) PMID:27303706 | |
| filamentous growth: decreased | systematic mutation set | null Allele: rps26a-Δ | Sigma1278b | Jin R, et al. (2008) PMID:17989363 | ||
| invasive growth: absent | systematic mutation set | null Allele: rps26a-Δ | Sigma1278b | Jin R, et al. (2008) PMID:17989363 | ||
| inviable | systematic mutation set | overexpression | S288C | Sopko R, et al. (2006) PMID:16455487 | ||
| vegetative growth: decreased rate | classical genetics | null Allele: rps26a-Δ | W303 | Details: micro-colonies barely visible after 5 days incubation | Wu M and Tan HM (1994) PMID:7821815 | |
| vegetative growth: decreased rate | classical genetics | null Allele: rps26a-Δ | Sigma1278b | Strittmatter AW, et al. (2006) PMID:16721598 | ||
| vegetative growth: increased rate | competitive growth fitness measured as the ratio of wild-type to mutant cells observed after 50 generations of growth in mixed cultures | gain of function | Other | Details: fitness is more than 110% that of wild type; mutant allele is a precise deletion of the intron | Parenteau J, et al. (2011) PMID:22000012 |
This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).
Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
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