Literature Help
MLC1 / YGL106W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Feng Z, et al. (2015) Myosin‑II heavy chain and formin mediate the targeting of myosin essential light chain to the division site before and during cytokinesis. Mol Biol Cell 26(7):1211-24 PMID:25631819
- Naylor SG and Morgan DO (2014) Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis. J Cell Sci 127(Pt 5):1128-37 PMID:24413167
- Fang X, et al. (2010) Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II. J Cell Biol 191(7):1333-50 PMID:21173112
- Altmann K, et al. (2008) The class V myosin motor protein, Myo2, plays a major role in mitochondrial motility in Saccharomyces cerevisiae. J Cell Biol 181(1):119-30 PMID:18391073
- Amata I, et al. (2008) N-lobe dynamics of myosin light chain dictates its mode of interaction with myosin V IQ1. Biochemistry 47(47):12332-45 PMID:18975975
- Casavola EC, et al. (2008) Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain. Mol Microbiol 67(5):1051-66 PMID:18221262
- Pennestri M, et al. (2007) Structural basis for the interaction of the myosin light chain Mlc1p with the myosin V Myo2p IQ motifs. J Biol Chem 282(1):667-79 PMID:17074768
- Bielli P, et al. (2006) GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway. Mol Microbiol 59(5):1576-90 PMID:16468996
- Ganoth A, et al. (2006) A molecular dynamics study and free energy analysis of complexes between the Mlc1p protein and two IQ motif peptides. Biophys J 91(7):2436-50 PMID:16844751
- Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 PMID:15210731
- Valouev IA, et al. (2004) Translation termination factors function outside of translation: yeast eRF1 interacts with myosin light chain, Mlc1p, to effect cytokinesis. Mol Microbiol 53(2):687-96 PMID:15228544
- Terrak M, et al. (2003) Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications. EMBO J 22(3):362-71 PMID:12554638
- Terrak M, et al. (2002) Crystallization, X-ray characterization and selenomethionine phasing of Mlc1p bound to IQ motifs from myosin V. Acta Crystallogr D Biol Crystallogr 58(Pt 10 Pt 2):1882-5 PMID:12351846
- Wagner W, et al. (2002) Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p. EMBO J 21(23):6397-408 PMID:12456647
- Bialek-Wyrzykowska U, et al. (2000) Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance. Mol Microbiol 35(6):1295-311 PMID:10760132
- Boyne JR, et al. (2000) Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis. J Cell Sci 113 Pt 24:4533-43 PMID:11082046
- Shannon KB and Li R (2000) A myosin light chain mediates the localization of the budding yeast IQGAP-like protein during contractile ring formation. Curr Biol 10(12):727-30 PMID:10873803
- Stevens RC and Davis TN (1998) Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae. J Cell Biol 142(3):711-22 PMID:9700160
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Joshua IM, et al. (2023) A Protein-Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20. Int J Mol Sci 24(21) PMID:37958899
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Muller R, et al. (2020) CiBER-seq dissects genetic networks by quantitative CRISPRi profiling of expression phenotypes. Science 370(6522) PMID:33303588
- Schmiedel JM, et al. (2019) Empirical mean-noise fitness landscapes reveal the fitness impact of gene expression noise. Nat Commun 10(1):3180 PMID:31320634
- Tian C, et al. (2014) Stepwise and cooperative assembly of a cytokinetic core complex in Saccharomyces cerevisiae. J Cell Sci 127(Pt 16):3614-24 PMID:24895401
- Heym RG, et al. (2013) In vitro reconstitution of an mRNA-transport complex reveals mechanisms of assembly and motor activation. J Cell Biol 203(6):971-84 PMID:24368805
- Goel A, et al. (2011) Four-dimensional visualisation and analysis of protein-protein interaction networks. Proteomics 11(13):2672-82 PMID:21630449
- Scherrer T, et al. (2011) Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Genome Biol 12(1):R3 PMID:21232131
- Jones LA and Sudbery PE (2010) Spitzenkorper, exocyst, and polarisome components in Candida albicans hyphae show different patterns of localization and have distinct dynamic properties. Eukaryot Cell 9(10):1455-65 PMID:20693302
- Michelot A, et al. (2010) Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol 20(21):1890-9 PMID:21035341
- Nishihama R, et al. (2009) Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae. J Cell Biol 185(6):995-1012 PMID:19528296
- Tully GH, et al. (2009) The anaphase-promoting complex promotes actomyosin-ring disassembly during cytokinesis in yeast. Mol Biol Cell 20(4):1201-12 PMID:19109423
- Pathmanathan S, et al. (2008) Interactions between the budding yeast IQGAP homologue Iqg1p and its targets revealed by a split-EGFP bimolecular fluorescence complementation assay. Cell Biol Int 32(10):1318-22 PMID:18675924
- Castrillo JI, et al. (2007) Growth control of the eukaryote cell: a systems biology study in yeast. J Biol 6(2):4 PMID:17439666
- Ganoth A, et al. (2007) Myosin V movement: lessons from molecular dynamics studies of IQ peptides in the lever arm. Biochemistry 46(50):14524-36 PMID:18020453
- Steigele S, et al. (2007) Comparative analysis of structured RNAs in S. cerevisiae indicates a multitude of different functions. BMC Biol 5:25 PMID:17577407
- Urakov VN, et al. (2006) N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination. BMC Mol Biol 7:34 PMID:17034622
- Altmann K and Westermann B (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7 PMID:16135527
- Crampin H, et al. (2005) Candida albicans hyphae have a Spitzenkörper that is distinct from the polarisome found in yeast and pseudohyphae. J Cell Sci 118(Pt 13):2935-47 PMID:15976451
- Melino S, et al. (2005) Assignment of the 1H, 13C and 15N resonances of Mlc1p from Saccharomices cerevisiae. J Biomol NMR 31(4):367-8 PMID:15929007
- Takahashi K, et al. (2004) Cellular signaling mediated by calphoglin-induced activation of IPP and PGM. Biochem Biophys Res Commun 325(1):203-14 PMID:15522220
- Desautels M, et al. (2001) Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe, interacts with a phosphatidylinositol 4-kinase. J Biol Chem 276(8):5932-42 PMID:11087749
Reviews
No reviews curated.
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Naylor SG and Morgan DO (2014) Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis. J Cell Sci 127(Pt 5):1128-37 PMID:24413167
- Tian C, et al. (2014) Stepwise and cooperative assembly of a cytokinetic core complex in Saccharomyces cerevisiae. J Cell Sci 127(Pt 16):3614-24 PMID:24895401
- Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 PMID:15210731
- Wagner W, et al. (2002) Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p. EMBO J 21(23):6397-408 PMID:12456647
- Boyne JR, et al. (2000) Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis. J Cell Sci 113 Pt 24:4533-43 PMID:11082046
- Shannon KB and Li R (2000) A myosin light chain mediates the localization of the budding yeast IQGAP-like protein during contractile ring formation. Curr Biol 10(12):727-30 PMID:10873803
- Stevens RC and Davis TN (1998) Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae. J Cell Biol 142(3):711-22 PMID:9700160
Phenotype Literature
Paper(s) associated with one or more pieces of classical phenotype evidence in SGD for the specified gene.
No phenotype literature curated.
Download References (.nbib)
- Fang X, et al. (2010) Biphasic targeting and cleavage furrow ingression directed by the tail of a myosin II. J Cell Biol 191(7):1333-50 PMID:21173112
- Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 PMID:15210731
- Boyne JR, et al. (2000) Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis. J Cell Sci 113 Pt 24:4533-43 PMID:11082046
- Stevens RC and Davis TN (1998) Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae. J Cell Biol 142(3):711-22 PMID:9700160
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Casler JC, et al. (2024) Mitochondria-ER-PM contacts regulate mitochondrial division and PI(4)P distribution. J Cell Biol 223(9) PMID:38781029
- Kelbert M, et al. (2024) The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay. Elife 12 PMID:39356734
- Marmorale LJ, et al. (2024) Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking. J Cell Biol 223(3) PMID:38240799
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Cohen N, et al. (2023) A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon. EMBO J 42(11):e113385 PMID:37073826
- Joshua IM, et al. (2023) A Protein-Protein Interaction Analysis Suggests a Wide Range of New Functions for the p21-Activated Kinase (PAK) Ste20. Int J Mol Sci 24(21) PMID:37958899
- Kolhe JA, et al. (2023) The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions. Mol Cell 83(12):2035-2044.e7 PMID:37295430
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Eyboulet F, et al. (2020) The deubiquitylase Ubp15 couples transcription to mRNA export. Elife 9 PMID:33226341
- Gingras RM, et al. (2020) Yeast Rgd3 is a phospho-regulated F-BAR-containing RhoGAP involved in the regulation of Rho3 distribution and cell morphology. Mol Biol Cell 31(23):2570-2582 PMID:32941095
- Glomb O, et al. (2020) The cell polarity proteins Boi1 and Boi2 direct an actin nucleation complex to sites of exocytosis in Saccharomyces cerevisiae. J Cell Sci 133(3) PMID:31964708
- Sanchez A, et al. (2020) Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation. Proc Natl Acad Sci U S A 117(48):30577-30588 PMID:33199619
- Bhalla P, et al. (2019) Interactome of the yeast RNA polymerase III transcription machinery constitutes several chromatin modifiers and regulators of the genes transcribed by RNA polymerase II. Gene 702:205-214 PMID:30593915
- Mönkemeyer L, et al. (2019) Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2. Mol Cell 74(1):88-100.e9 PMID:30876804
- Pereira F, et al. (2019) Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation. PLoS One 14(1):e0211180 PMID:30682149
- Rössler I, et al. (2019) Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME. Nucleic Acids Res 47(13):6984-7002 PMID:31062022
- Gonzales-Zubiate FA, et al. (2017) Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae. J Biol Chem 292(29):12267-12284 PMID:28539363
- Jungfleisch J, et al. (2017) A novel translational control mechanism involving RNA structures within coding sequences. Genome Res 27(1):95-106 PMID:27821408
- Sturm M, et al. (2017) Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly. Nat Commun 8(1):2213 PMID:29263326
- Santiago E, et al. (2016) Novel Interactome of Saccharomyces cerevisiae Myosin Type II Identified by a Modified Integrated Membrane Yeast Two-Hybrid (iMYTH) Screen. G3 (Bethesda) 6(5):1469-74 PMID:26921299
- Sung MK, et al. (2016) A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins. Elife 5 PMID:27552055
- Neller J, et al. (2015) A protein complex containing Epo1p anchors the cortical endoplasmic reticulum to the yeast bud tip. J Cell Biol 208(1):71-87 PMID:25547157
- Elbaz-Alon Y, et al. (2014) A dynamic interface between vacuoles and mitochondria in yeast. Dev Cell 30(1):95-102 PMID:25026036
- Kurat CF, et al. (2014) Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation. Proc Natl Acad Sci U S A 111(39):14124-9 PMID:25228766
- Naylor SG and Morgan DO (2014) Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis. J Cell Sci 127(Pt 5):1128-37 PMID:24413167
- Tian C, et al. (2014) Stepwise and cooperative assembly of a cytokinetic core complex in Saccharomyces cerevisiae. J Cell Sci 127(Pt 16):3614-24 PMID:24895401
- Makanae K, et al. (2013) Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method. Genome Res 23(2):300-11 PMID:23275495
- Qiu J, et al. (2013) Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation. Cell 154(3):596-608 PMID:23911324
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Kaluarachchi Duffy S, et al. (2012) Exploring the yeast acetylome using functional genomics. Cell 149(4):936-48 PMID:22579291
- Schenk L, et al. (2012) La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast. RNA 18(3):449-61 PMID:22271760
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- García-Gómez JJ, et al. (2011) Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae. Mol Cell Biol 31(20):4156-64 PMID:21825077
- Hruby A, et al. (2011) A constraint network of interactions: protein-protein interaction analysis of the yeast type II phosphatase Ptc1p and its adaptor protein Nbp2p. J Cell Sci 124(Pt 1):35-46 PMID:21118957
- Ren L, et al. (2011) Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS One 6(2):e16719 PMID:21386897
- Sammons MA, et al. (2011) Saccharomyces cerevisiae Gis2 interacts with the translation machinery and is orthogonal to myotonic dystrophy type 2 protein ZNF9. Biochem Biophys Res Commun 406(1):13-9 PMID:21277287
- Scherrer T, et al. (2011) Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Genome Biol 12(1):R3 PMID:21232131
- Stark BC, et al. (2011) Functional adaptation between yeast actin and its cognate myosin motors. J Biol Chem 286(35):30384-30392 PMID:21757693
- Breitkreutz A, et al. (2010) A global protein kinase and phosphatase interaction network in yeast. Science 328(5981):1043-6 PMID:20489023
- Michelot A, et al. (2010) Reconstitution and protein composition analysis of endocytic actin patches. Curr Biol 20(21):1890-9 PMID:21035341
- Ossareh-Nazari B, et al. (2010) Cdc48 and Ufd3, new partners of the ubiquitin protease Ubp3, are required for ribophagy. EMBO Rep 11(7):548-54 PMID:20508643
- Batisse J, et al. (2009) Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure. J Biol Chem 284(50):34911-7 PMID:19840948
- Casavola EC, et al. (2008) Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain. Mol Microbiol 67(5):1051-66 PMID:18221262
- Pathmanathan S, et al. (2008) Interactions between the budding yeast IQGAP homologue Iqg1p and its targets revealed by a split-EGFP bimolecular fluorescence complementation assay. Cell Biol Int 32(10):1318-22 PMID:18675924
- Yu H, et al. (2008) High-quality binary protein interaction map of the yeast interactome network. Science 322(5898):104-10 PMID:18719252
- Bielli P, et al. (2006) GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway. Mol Microbiol 59(5):1576-90 PMID:16468996
- Gavin AC, et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 440(7084):631-6 PMID:16429126
- Krogan NJ, et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440(7084):637-43 PMID:16554755
- Terrak M, et al. (2005) Structure of the light chain-binding domain of myosin V. Proc Natl Acad Sci U S A 102(36):12718-23 PMID:16120677
- Luo J, et al. (2004) Identification and functional analysis of the essential and regulatory light chains of the only type II myosin Myo1p in Saccharomyces cerevisiae. J Cell Biol 165(6):843-55 PMID:15210731
- Valouev IA, et al. (2004) Translation termination factors function outside of translation: yeast eRF1 interacts with myosin light chain, Mlc1p, to effect cytokinesis. Mol Microbiol 53(2):687-96 PMID:15228544
- Terrak M, et al. (2003) Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications. EMBO J 22(3):362-71 PMID:12554638
- Gavin AC, et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415(6868):141-7 PMID:11805826
- Ho Y, et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415(6868):180-3 PMID:11805837
- Terrak M, et al. (2002) Crystallization, X-ray characterization and selenomethionine phasing of Mlc1p bound to IQ motifs from myosin V. Acta Crystallogr D Biol Crystallogr 58(Pt 10 Pt 2):1882-5 PMID:12351846
- Wagner W, et al. (2002) Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p. EMBO J 21(23):6397-408 PMID:12456647
- Bialek-Wyrzykowska U, et al. (2000) Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance. Mol Microbiol 35(6):1295-311 PMID:10760132
- Boyne JR, et al. (2000) Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis. J Cell Sci 113 Pt 24:4533-43 PMID:11082046
- Shannon KB and Li R (2000) A myosin light chain mediates the localization of the budding yeast IQGAP-like protein during contractile ring formation. Curr Biol 10(12):727-30 PMID:10873803
- Stevens RC and Davis TN (1998) Mlc1p is a light chain for the unconventional myosin Myo2p in Saccharomyces cerevisiae. J Cell Biol 142(3):711-22 PMID:9700160
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Garcia JM, et al. (2021) A functional genomic screen in Saccharomyces cerevisiae reveals divergent mechanisms of resistance to different alkylphosphocholine chemotherapeutic agents. G3 (Bethesda) 11(10) PMID:34568930
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- MacIsaac KD, et al. (2006) An improved map of conserved regulatory sites for Saccharomyces cerevisiae. BMC Bioinformatics 7:113 PMID:16522208
- Altmann K and Westermann B (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7 PMID:16135527