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NUP145 / YGL092W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
nucleocytoplasmic transporter NUP145
Feature Type
ORF , Verified
Essential protein with distinct roles in two nuclear pore subcomplexes; catalyzes its own proteolytic cleavage in vivo to generate a C-terminal fragment that is a structural component of the Nup84p subcomplex (with roles in NPC biogenesis and localization of genes to the nuclear periphery), and an N-terminal fragment that is one of several FG-nucleoporins within the NPC central core directly responsible for nucleocytoplasmic transport; homologous to human NUP98 3 4 6 7 8 9 10 11