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PDR1 / YGL013C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
AMY1 19 , ANT1 20 , BOR2 21 , CYH3 22 , NRA2 , SMR2 , TIL1 , TPE1 23 , TPE3
Protein Product
drug-responsive transcription factor PDR1
Feature Type
ORF , Verified
Description
Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication 2 3 4
Paralog
PDR3 3

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